Mucosal Immunology is the official publication of the Society of Mucosal Immunology (SMI). It aims to provide a forum for both basic and clinical scientists to discuss all aspects of immunity and inflammation involving mucosal tissues.
In just the past several years, SIgA has been identified as having the capacity to directly quench bacterial virulence factors, influence composition of the intestinal microbiota by Fab-dependent and Fab-independent mechanisms, promote retro-transport of antigens across the intestinal epithelium to dendritic cell subsets in gut-associated lymphoid tissue, and, finally, to downregulate proinflammatory responses normally associated with the uptake of highly pathogenic bacteria and potentially allergenic antigens.
CD161++CD8+ T cells are a tissue-infiltrating population that produce IL17A, IL22, IFNγ, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the semi-invariant TCR Vα7.2, the canonical ...
Typhoid fever, caused by S. Typhi, is responsible for approximately 200,000 deaths per year worldwide. Little information is available regarding epithelium-bacterial interactions in S. Typhi infection.
Mucosal Immunology is the official publication of the Society of Mucosal Immunology (SMI). It aims to provide a forum for both basic and clinical scientists to discuss all aspects of immunity and inflammation involving mucosal tissues.
PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Each month, the Editors of the Journal of Allergy and Clinical Immunology will select two JACI articles for discussion. Readers are invited to send in their questions and comments, which will be addressed by the authors.
Mucosal immunity has been acknowledged as extremely important in disease prevention but has been somewhat limited due to the degradation of the vaccine and its limited uptake. Encapsulation of these vaccines into either ...
Defect in immune memory may cause repeat bladder infections EurekAlert (press release) But it has not been among the organs considered "immune privileged," in which the immune system operates under special strategies for tolerating certain...
PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Oral Candida infection weakens tooth enamel News-Medical.net Castro et al hypothesized that since C. albicans has a high acidogenic potential, infection with the pathogen could contribute to the demineralization of tooth surfaces.
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
In particular, purification or production of large quantities of secretory IgA (SIgA) for potential mucosal application has not been achieved. In this work, we sought to investigate whether polymeric IgA (pIgA) recovered from ...
Human Breast Milk: Current Concepts of Immunology and Infectious Diseases. Robert M. Lawrence, MD,a and Camille A. Pane, MDb. T his is a review of the immunologic activities and protective benefits of human breast milk against infection.
The gut mucosa hosts the body's largest population of immune cells. Nature Immunology in collaboration with Arkitek Studios have produced an animation unrave...
Microbiology's Mestecky leads this years honorees for Service Awards recognition UAB News “When we started with mucosal immunology it was considered to be a somewhat strange area of research,” Mestecky says.
Thus, ARV synbiotic supplementation in HIV-infected individuals may improve GI tract immunity and thereby mitigate inflammatory sequelae, ultimately improving prognosis. See the related ...
Researchers crack olfactory code for partner selection, synthesise first ... Phys.Org The sensory cells of the olfactory mucosa are actually capable of identifying certain protein ligands known as peptides.
Vaccine News Daily (blog) A Novel Pathway for a Mucosal TB Vaccine Newswise (press release) “We can direct the type of immune response to the vaccine that is desired, whether an antibody response or a cellular response, simply by choosing one or...
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