I2BC Paris-Saclay

We’re excited to announce that registrations are now open for the Second Interdisciplinary Summer School: ChemPhysBio2025 – Imaging Biology: Interdisciplinary Tools and Techniques to Unravel Cellular Dynamics – taking place June 16–20, 2025, at Université Paris-Saclay!

This unique event bridges chemistry, physics, and biology, offering participants the opportunity to explore advanced photonic imaging techniques for unraveling cellular dynamics.

We’re also thrilled to welcome two distinguished guest lecturers:

• Julie Karpenko (Laboratory for Therapeutic Innovation, University of Strasbourg)
• Balázs Enyedi (Department of Physiology, Semmelweis University, Hungary)

What to expect?

• Inspiring lectures and research seminars
• Interactive interdisciplinary workshops
• Hands-on experience in cutting-edge research labs

Who should apply?
Master’s students, PhD candidates, postdocs, and junior researchers who are newcomers to the interdisciplinary field and eager to deepen their knowledge, expand their skill sets, and build meaningful collaborations.

With only 20 spots available, don’t miss your chance to join us!
Apply now: https://chemphysbio2025.sciencesconf.org/

Learn with great scientists about cell mechanotransduction and microbial invasion processes

Morning session: Cell Mechanotransduction 9H00-9H30 : Christophe Leclainche, I2BC, Gif-sur-Yvette.
Understanding mechanotransduction through in vitro reconstitution of actomyosin-dependent protein machineries
9H30-10H00 : Benoit Ladoux, MPZPM, Erlangen, Germany.
Mechanical imprints of cell extrusion from epithelial tissues.
10H00-10H30 : Patricia Bassereau, Institut Curie, Paris.
Cell spreading on fluid membranes requires strong integrin ligands and microtubules
10H30-10H50 : Coffee break
10H50-11H20: Gregory Giannone, Université de Bordeaux.
Unraveling the nanoscale spatial and mechanical regulation of actin binding proteins.
11H20-12H00 : Keynote lecture - Michael Sheetz, UTMB, Texas, USA.
Mechanical Oscillations Kill Cancer Cells and Reverse Aging
 
Afternoon session « Microbial Invasion»

14H00-14H30 : Sven Hammerschmidt, Greifswald university, Germany
TBA
14H30-15H00 :  Sandrine Bourdoulous, Institut Cochin, Paris.
Angptl4 prevents endothelial dysfunction during bacterial sepsis
15H00-15H40 : Keynote lecture - Linda Kenney, UTMB, Texas, USA.
Imaging Salmonella Lifestyles: From Virulence to Biofilms to Tumors
15H40-16H00 : Coffee break
16H00-16H30 : Jost Enninga, Institut Pasteur, Paris.
Endomembrane breakage by enteroinvasive bacterial pathogens- new insights by in cellulo structural biology
16H30-17H00 : Marc Prudhomme, Université Paul Sabatier, Toulouse
Bacterial communication and antibiotic tolerance in Pneumooccus
17H00-17H30 : Guy Tran Van Nhieu, I2BC, Gif-sur-Yvette.
Characterization of pneumococcal secreted factors associated with bacterial meningitis

more information: https://archaea2024.sciencesconf.org/

Contact: tamara.basta@i2bc.paris-saclay.fr

The I2BC will be present at the Fête de la Science on 5 and 6 October 2024 at ENS Paris-Saclay (4 avenue des sciences- Gif sur Yvette) on the theme ‘Ocean of knowledge’. The Microbiology Department and the Crystallography Platform will each have a stand entitled ‘Can bacteria swim?’ and ‘Making and observing protein crystals’, where the public can carry out experiments, look under a microscope and take part in games.

more information: https://www.fetedelascience.fr/

Contact: catherine.grandclement@i2bc.paris-saclay.fr

October 14th -16th

Site Henri Moissan Université Paris-Saclay Orsay

More information: https://www.universite-paris-saclay.fr/evenements/physchemcell2024

Mark your calendars for Jun. 26-28, 2024! Join us at Ecole Polytechnique in Palaiseau for the 7th International Conference on Physics and Biological Systems, where top-notch scientists converge to explore the dynamic interplay between physics and life sciences.

The 7th International Conference on Physics and Biological Systems will be held on Jun. 26-28 2024 at Ecole Polytechnique in Palaiseau, in the south of Paris. It aims to bring together a broad range of physical and life scientists working at the interface between the two disciplines around in-depth talks by first-rate international speakers. Attendance will be limited to 200 participants. We look forward to welcoming you in Palaiseau!

more information: https://www.lptms.universite-paris-saclay.fr/physbio2024/

contact: Pavel MULLER <pavel.muller@i2bc.paris-saclay.fr>

The registration in now open for the next EMBO conference "Molecular Biology of Archaea" that will take place near Paris (Palaiseau) on 23-27th of june 2024! 

Archaea are fascinating organisms with a bacteria-like morphology, but information-processing systems that are homologous to eukaryotic counterparts, for instance replication, transcription and translation. Recently, novel groups of archaea (e.g. Asgard archaea) have been discovered that represent the closest living relatives to eukaryotes and shed new light on their evolution. Archaeal research has led to seminal change-of-concept mechanistic discoveries in the area of molecular biology, and many studies are currently aiming to unravel the global environmental impact of archaea. Their viruses have a remarkable diversity of morphotypes, exceeding that of bacterial or eukaryotic viruses.The EMBO Workshop on Molecular biology of Archaea will cover cutting-edge research in various fields with a focus on archaeal molecular biology, evolution, and ecology and their interconnections. The proposed talks will present data at different scales ranging from single molecule and structural studies to archaeal physiology, metabolism and ecological impact. This is of high interest as molecular studies of archaea are a very active field, reflecting the wealth of metagenomics information revealing novel biology that can now be addressed by the latest experimental and computational techniques.

all information:

https://meetings.embo.org/event/24-archaea

contact: Tamara BASTA-LE BERRE <tamara.basta@i2bc.paris-saclay.fr>

As part of the 4th edition of the Visites Insolites du CNRS, the "Molecular Microbiology of Actinobacteria" team (I2BC, Microbiology Department) welcomed members of the public to its laboratory on 11 and 12 october.
Using five interactive workshops, participants were able to find out how experiments are done in a microbiology lab, observe different species of bacteria under the microscope and carry out a DNA extraction. They also learned how new antibiotics are discovered and what mechanisms bacteria develop to become resistant to antibiotics. Finally, they were able to learn about synthetic biology and invent the antibiotics of tomorrow using Duplo bricks!

This conference is postponed to a later date.

The next Cyclope conference organized by the CEA will be presented by Marie-Hélène Le DU at the INSTN at 8 p.m on the 24th of October 2023. The headline: “Proteins are everywhere".

They are found in animals as well as plants, bacteria or viruses. They allow the regular beating of your heart, the digestion of your last meal, maintain your body at a constant temperature, participate in the fight against infections that threaten you and much more...
Proteins are everywhere life exists and science has studied them for decades, but they are so numerous and so diverse that their world has yet to be explored. We invite you to discover this exciting research in the company of Marie-Hélène Le Du, CEA researcher at the Institute of Integrative Cell Biology (DRF/Joliot/I2BC), with the participation of Rémi Ruedas, a doctoral student at I2BC.

Registration open, here

Bringing together researchers working on fundamental, translational and clinical research in the field of “Microbiota”.

The symposium is organized by the GS LSH and the OI MICROBES on Wednesday, May 31, 2023 at Henri Moissan, and aims to bring together researchers from different fields (basic research, translational and clinical research) working on the topic of “Microbiota”. The objective of the symposium is to provide the opportunity to the different communities to know each other and to initiate collaborations in the future.

Registration is free but mandatory: https://www.universite-paris-saclay.fr/actualites/environment-and-host-microbiomes-functional-interactions

Young researchers (PhD students and Post-Doc) are invited to present their research as a poster (abstract to be submitted before May 5, 2023 online: https://cirrus.universite-paris-saclay.fr/s/58tPW6HpnS2Fbz8)    

Contact: Peter MERGAERT <peter.mergaert@i2bc.paris-saclay.fr>

The program is online here

The Graduate School Life Sciences & Health of the Université Paris-Saclay organizes a scientific day about Single-cell & Spatial-omics.

On Tuesday the 19th of November, the Graduate School Life Sciences and Health (GS LSH) of the Université Paris-Saclay is organizing its 8th scientific day, which is dedicated to “Single-cell and spatial-omics”. During the symposium, speakers from Université Paris-Saclay institutes and elsewhere will present their work involving single-cell and spatial -omics technologies. As part of the day, I2BC team leaders Kasia Siudeja and Joana Santos will present their work on the aging process in Drosophila and the infection cycle of the Malaria parasite. The day will take place in the Henri Moissan building on the Université Paris-Saclay campus. Participation is free, but registration is mandatory.

Registration: https://forms.office.com/e/6T3rVgPAYE

More information: https://openagenda.com/fr/universite-paris-saclay/events/journee-scientifique-gs-lsh-single-cell-and-spatial-omics

Gif-sur-Yvette B22 N001

Une expérience surprenante avec les sciences! Les Visites insolites du CNRS vous proposent chaque année des expériences uniques, en groupe restreint, au cœur des laboratoires de recherche pour vivre des moments privilégiés avec les scientifiques.

Si on vous dit « microbes » ou « bactéries », vous pensez généralement aux pathogènes, causes de nombreuses maladies et de grandes épidémies dans l’histoire de l’humanité (peste, lèpre, tuberculose…) ? Et pourtant, les micro-organismes ne sont pas toujours nos ennemis, certaines bactéries sont même à l’origine de nombreux antibiotiques ! Si lors de leurs découvertes dans les années 1950-1970, nous avons cru gagner la bataille contre les bactéries pathogènes, ces dernières résistent et ne sont plus sensibles aux antibiotiques actuels. Alors comment recherche-t-on de nouveaux antibiotiques ? Comment étudie-t-on les bactéries qui les fabriquent ? Quels sont les mécanismes de résistance des bactéries pathogènes ? Peut-on faire fabriquer de nouveaux antibiotiques à des bactéries ? Venez découvrir la réponse à certaines de ces questions au travers d’observations et de discussions avec des membres du laboratoire !

more information: https://visitesinsolites.cnrs.fr/visite/sous-la-loupe-du-laboratoire-secrets-et-defis-des-antibiotiques/

Want to learn more about the third domain of life, the Archaea? Join us at I2BC for an annual symposium gathering French research community studying archaea.

The Archaea 2024 symposium, organised by the SFBBM's GT-Archées, is intended to bring together the entire French scientific community to discuss and exchange ideas on unifying themes relating to the importance and place of Archaea, the third domain of living organisms, in ecosystems, evolution and the fundamental processes of life. The scientific community is seeking to elucidate the fundamental molecular mechanisms at work in these microorganisms, the diversity of their viruses, and the adaptive limits of living organisms in relation to the environment. Archaea have been the subject of study from a variety of disciplinary perspectives, including those of biochemists, microbiologists, evolutionists, molecular biologists and also from the perspective of industry. Archaea are now being regarded as essential models for understanding the processes that underpin the functioning of living organisms.

more information: https://archaea2024.sciencesconf.org/

Contact: tamara.basta@i2bc.paris-saclay.fr

As part of the "Jeudis de la Recherche" organized by the COMPAS (Paris-Saclay University), the CNRS and the town of Gif sur Yvette, Sylvie Lautru's team (I2BC, Microbiology Department) welcomed around twenty people to take part in 5 workshops on the theme of "Antibiotics and the microbial response: a never-ending battle". Thanks to the very interactive format, participants who were very interested in this topical issue, asked many questions and exchanged a lot with the research team.

https://www.ville-gif.fr/215/que-faire-a-gif/culture/conferences/jeudis-de-la-recherche.htm

On Saturday 7 and Sunday 8 October 2023, the Department of Microbiology of I2BC participated to the Fête de la Science in the Village des Sciences in Gif sur Yvette and the Faculté des Sciences in Orsay.
Various workshops and games enabled the public to discover that bacteria appeared long before the dinosaurs, that they are everywhere, and that they provide many beneficial services. They were able to learn that there are bacteria even in the clouds, that they help us to produce our everyday food and that some even help plants to grow.

I2BC hosted Agrobacterium2023 from the 18th to the 20th of September. Agrobacterium2023 is a joint event of the 43rd American Crown Gall Meeting and the 4th European Agrobacterium Conference. This meeting brought together scientists from Europe, the USA, and China working in all aspects of Agrobacterium biology, from basic science to applied fields in agronomy and genome editing technologies. The meeting also welcomed students from the Master Plant Sciences program at the University Paris-Saclay.

Registration open until May 15, 2023: https://www.azur-colloque.fr/DR04/inscription/inscription/258

Self-assembled molecular systems are studied in various fields ranging from physics to biology, including chemistry, mathematics and materials science. While the properties (mechanical, biological) of complex molecular assemblies are already the subject of well-established scientific fields, the study of the dynamic phenomena leading to their formation and evolution over time remains a field in genesis. However, this is not only a field of fundamental scientific interest, but also of practical interest, such as for pathological assemblies or assemblies with therapeutic or (bio)technological purposes. For more details on MéDynA : https://medyna.cnrs.fr/

More information: here

Location: Institute for Integrative Biology of the Cell (I2BC), Building 21, avenue de la Terrasse, 91190 Gif-sur-Yvette, France

Scientific context: Agrobacterium and its relatives have been fascinating the scientists for more than century. These bacteria evolved a unique capacity to genetically modify the infected plants to force them to become a welcoming host. From studies on the interaction processes between Agrobacterium and its hosts, exceptional scientific advances in biology and biotechnology have emerged and some others still occur today.

Objectives: Agrobacterium 2023 is a joint event of the 43rd American Crown gall meeting and the 4th European Agrobacterium Conference. This meeting will bring together French and international scientists working in all aspect of Agrobacterium biology: from basic science to applied fields in agronomy and genome editing technologies.

Topics:        Pathology: plant damage and protection
Host-microbes signaling: cell and genome reprograming
Genome biology: architecture, evolutionary biology and taxonomy
Cell biology and structural biology: molecular machineries
Genetic engineering: DNA delivery and recombination

Contact: Denis Faure <denis.faure@i2bc.paris-saclay.fr>