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Scooped by
Ed Rybicki
January 31, 2022 8:27 AM
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Jeffrey Taubenberger (NIAID) and John Oxford (QMUL) are invited to speak at The Norwegian Academy of Science and Letters as guests of Mamelund’s CAS project.Supported by the Centre for Advanced Study (CAS) at The Norwegian Academy of Science and Letters.‘The influenza...
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Scooped by
Ed Rybicki
January 24, 2022 9:47 AM
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The amount of highly pathogenic avian influenza outbreaks in Europe in 2021 quadrupled that of 2020.
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Scooped by
Ed Rybicki
January 24, 2022 9:46 AM
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A repository of stories of anti-vaxxers who died or came close to dying of COVID.
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Scooped by
Ed Rybicki
January 24, 2022 9:44 AM
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A new study clarifies how L-dopa, the front-line drug for Parkinson's disease, also contributes to the rapid decline in quality of life over time.
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Scooped by
Ed Rybicki
January 24, 2022 9:42 AM
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LYNCHBURG, VA—Astounded by the damning information, local anti-vaxxer Pete Dixon was reportedly horrified Thursday after discovering that every single American who got a smallpox vaccine in the 19th century was now deceased.
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Scooped by
Ed Rybicki
January 21, 2022 5:23 AM
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Author summary Interferon responses are part of the primary host defenses against infections. However, excessive inflammation is often a major factor in severe disease or even death in respiratory infections such as influenza, as it can lead to acute respiratory distress syndrome and sepsis-like...
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Scooped by
Ed Rybicki
January 21, 2022 5:22 AM
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Influenza has returned to Europe at a faster-than-expected rate this winter after almost disappearing last year, raising concerns about a prolonged "twindemic" with COVID-19 amid some doubts about the effectiveness of flu vaccines.
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Scooped by
Ed Rybicki
January 21, 2022 5:22 AM
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Moderna aims to roll out a combined Covid-flu-RSV booster vaccine in late 2023, the US pharmaceutical firm said Monday, hoping a joint jab...
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Scooped by
Ed Rybicki
January 21, 2022 5:21 AM
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Flu outbreaks continue to be a major crisis in the poultry industry.The year didn't start so well for poultry farmers in Burkina Faso, not only did it affect...
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Scooped by
Ed Rybicki
January 21, 2022 5:20 AM
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This terrible Covid and flu season is a preview of the post-pandemic normal.
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Scooped by
Ed Rybicki
January 21, 2022 5:19 AM
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Better to wash hands than wait for a vaccine with this potential pandemic...
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Scooped by
Ed Rybicki
January 21, 2022 5:18 AM
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CORBEVAX uses recombinant DNA technology that many countries already have the infrastructure to produce. Artis777 via iStock/Getty Images PlusThe world now has a new COVID-19 vaccine in its arsenal, and at a fraction of the cost per dose.
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Scooped by
Ed Rybicki
January 21, 2022 5:16 AM
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Porcine circovirus type 3 (PCV3), a novel circovirus, imposes great burdens on the global pig industry. The penside tests for detecting PCV3 are critical for assessing the epidemiological status and working out disease prevention and control programs due to the unavailability of a commercial...
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Scooped by
Ed Rybicki
January 24, 2022 9:47 AM
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A Johnson and Johnson COVID-19 vaccine booster shot is 85% effective in protecting against being hospitalised by the Omicron variant for 1-2 months after it is received, the head of South Africa's Medical Research Council (SAMRC) said on Friday.
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Scooped by
Ed Rybicki
January 24, 2022 9:46 AM
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Flow cytometric data were analyzed using FlowJo version 10.7.1 (BD Biosciences). Multiplex cytokine bead data were analyzed using the LEGENDplex Data Analysis Software Suite (BioLegend). Statistical analyses were performed using GraphPad Prism version 9.1.1. Δ in figures represents values for which the corresponding background signal for each donor had been subtracted. “Background signal” is defined as the frequency of cells expressing the parameter being analyzed, or concentration of an analyte, in negative control wells. For each donor, the response is reported as the Δ after background subtraction for that donor. A T cell response was defined as positive if the value was two times background for that sample, and above a minimal level of 0.003%, which is calculated as the median of all DMSO controls. To calculate the rate of decay of the CD4 T cell responses based on ICC responses, we focused only on the stronger responses, and we only included donors whose response was 2 SDs above the median background. For proliferation data, in calculating the distribution of CD4 or CD8 subsets, only positive results were included, defined as above. For the multiplex data, the limit of detection was established using a standard curve for each analyte. Pairwise comparisons were made by a two-tailed Wilcoxon test or a nonparametric Dunn’s multiple comparisons test. Correlation analyses were performed by computing the Spearman correlation coefficient. For longitudinal data, the percentage change over time and t1/2 were calculated after linear regression was performed for each donor. We report the average percentage change per week and the average t1/2. Cluster analysis for multiplex data were performed by first calculating fold change in response to an Ag and then performing hierarchical agglomerative clustering on log-transformed data. Values across donors were standardized by minimum/maximum normalization such that, for each analyte, the minimum is subtracted, then divided by its maximum. These data were visualized using the Seaborn data visualization library for Python (https://joss.theoj.org/papers/10.21105/joss.03021).
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Scooped by
Ed Rybicki
January 24, 2022 9:46 AM
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Moderna is poised to commercialize its COVID-19 and influenza combination vaccine by the fall of 2023, with some potential for the same drug to also be viable against the RSV.
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Scooped by
Ed Rybicki
January 24, 2022 9:43 AM
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The increasing virulence of SARS-CoV-2 VOCs will lead to a considerably larger, and more deadly, pandemic than would have occurred in the absence of the emergence of VOCs.
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Scooped by
Ed Rybicki
January 24, 2022 9:42 AM
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It would have been hard to know in March 2020 that Covid-19 testing limitations in New York City would help lead doctors at Montefiore Medical Center in the Bro...
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Scooped by
Ed Rybicki
January 21, 2022 5:23 AM
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The 1918 Influenza epidemic in South Africa exacerbated existing large racial inequalities in access to institutionalized medical treatment...
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Scooped by
Ed Rybicki
January 21, 2022 5:22 AM
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Novak Djokovic risks being frozen out of tennis as he chases a record 21st Grand Slam title, with rules on travellers who are unvaccinated against COVID-19 tightening in the third year of the pandemic and some tournaments reconsidering exemptions.
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Scooped by
Ed Rybicki
January 21, 2022 5:21 AM
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Two vaccines will soon be tested in France in response to the worst avian influenza outbreak Europe has ever faced, French Agriculture Minister Julien Denormandie has announced. The aim is for them to be approved for all 27 EU member states.
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Scooped by
Ed Rybicki
January 21, 2022 5:21 AM
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Expert at Sheba Medical Center says jab raises COVID antibody levels, but there are ‘still a lot of infections’ among those who received it...
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Scooped by
Ed Rybicki
January 21, 2022 5:20 AM
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Vets had the unfortunate task of putting down 26 of the swans on the Thames after six were pulled from the river earlier in January...
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Scooped by
Ed Rybicki
January 21, 2022 5:19 AM
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A repurposed ADHD medication that boosts norepinephrine levels could stall neurodegeneration in people with early signs of Alzheimer’s disease.
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Scooped by
Ed Rybicki
January 21, 2022 5:17 AM
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"Doomscrolling" isn't just a new name for an existing behavior, researchers say. It's a unique behavior all its own, according to a new study.
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