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Scooped by
Ed Rybicki
November 21, 2024 4:40 AM
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Scientists from the Biology Centre of the Czech Academy of Sciences found forty new freshwater viruses infecting aquatic microorganisms this year. The first one, which they isolated and described in detail, was named Budvirus after the South Bohemian capital České Budějovice. It belongs to "Giant Viruses" and it infects unicellular algae called cryptophytes.
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Scooped by
Ed Rybicki
November 21, 2024 4:39 AM
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The Ebola virus (EBOV) causes severe disease in humans, and animal models are needed to evaluate the efficacy of vaccines and therapeutics. While non-human primate (NHP) and rodent EBOV infection models have been well characterized, there is a growing need for an intermediate model.
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Scooped by
Ed Rybicki
November 13, 2024 9:54 AM
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Next-generation metagenomic sequencing test developed at UCSF proves its effectiveness in quickly diagnosing almost any kind of pathogen.
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Scooped by
Ed Rybicki
November 13, 2024 9:53 AM
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Researchers at UCSF have developed a single genomic test that can quickly detect virtually any kind of pathogen in a patient. This allows for much quicker diagnoses, enables targeted treatment to begin sooner, and could lower healthcare costs.
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Scooped by
Ed Rybicki
November 13, 2024 9:53 AM
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Scientists from Université de Lille, France, Linköping University, Sweden, and collaborating institutions have introduced MassiveFold, a new version of AlphaFold that dramatically reduces computing time for protein structure predictions from months to hours.
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Scooped by
Ed Rybicki
October 31, 2024 11:09 AM
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The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response. Investigating how the unique structure of the ER arises and supports its function is critical to developing a mechanistic understanding of the many neurological diseases associated with ER structural perturbations.
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Scooped by
Ed Rybicki
October 31, 2024 11:08 AM
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One of the main challenges of contemporary medicine is posed by the resistance of pathogens to antibiotics. An important step in countering it has now been made by researchers from IOCB Prague, in collaboration with colleagues from the Institute of Microbiology and the Institute of Biotechnology of the Czech Academy of Sciences.
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Scooped by
Ed Rybicki
October 31, 2024 11:07 AM
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In recent years, bio-medical engineers have been developing promising techniques that could help diagnose diseases or precisely target specific regions inside the human body. Among these promising therapeutic strategies are methods that rely on the use of nanoparticles (NPs), tiny particles between 1 and 100 nm in size.
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Scooped by
Ed Rybicki
October 31, 2024 11:06 AM
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Northeastern University professors of pharmacy say the updated COVID-19 vaccines available for fall and winter of 2024 are a good match for the dominant strain of SARS-CoV-2 currently in circulation.
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Scooped by
Ed Rybicki
October 23, 2024 9:43 AM
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Science and Nature, two leading science journals, have revealed a growing problem: an alarming rise in fraudulent research papers produced by shady paper mill companies. This wave of fake studies is creating a major headache for the academic world, putting the integrity of global academic research at risk.
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Scooped by
Ed Rybicki
October 23, 2024 9:42 AM
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SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses. The discovery may point the way to the development of more effective...
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Scooped by
Ed Rybicki
October 23, 2024 9:40 AM
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During the COVID-19 pandemic, veterinary diagnostic laboratories tested both human and animal samples and needed to ensure that they could accurately perform large numbers of diagnostic tests in a timely manner.
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Scooped by
Ed Rybicki
October 23, 2024 9:39 AM
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Strategy for enhancing immune cell infiltration could be combined with other methods to improve cell-based immunotherapies against solid tumors.
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Scooped by
Ed Rybicki
November 21, 2024 4:39 AM
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The initial presentation of COVID-19 to the world left many in the medical community perplexed about its true nature and potential impact on individuals. Many investigations into the pathology of the virus resulted from this; however, studies were limited in the obstetric community, especially in...
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Scooped by
Ed Rybicki
November 13, 2024 9:55 AM
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"Very high" levels of the virus were detected by the CDC in New Mexico, with "high" levels in Oregon, Arkansas, and Maine.
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Scooped by
Ed Rybicki
November 13, 2024 9:54 AM
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Between 2013 and 2016, the A/H1N1pdm09 component of the live attenuated influenza vaccine (LAIV) produced instances of lower-than-expected vaccine effectiveness. Standard pre-clinical ferret models, using a human-like vaccine dose and focusing on antigenic match to circulating wildtype (wt)...
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Scooped by
Ed Rybicki
November 13, 2024 9:53 AM
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The virus takes control of three key host proteins that suppress the activity of the complement system.Researchers at the Medical University of Vienna and the Medical University of Innsbruck have found that SARS-CoV-2 manipulates three critical host proteins that normally suppress the activity of...
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Scooped by
Ed Rybicki
November 13, 2024 9:53 AM
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The following is a summary of “Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers’ SARS-CoV-2 lateral flow devices concurrently and nested viral culture study,” published in the November 2024 issue of...
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Scooped by
Ed Rybicki
October 31, 2024 11:08 AM
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Energy-making chloroplasts from algae have been inserted into hamster cells, enabling the cells to photosynthesize light, according to new research in Japan. It was previously thought that combining chloroplasts (chlorophyll containing structures in the cells of plants and algae) with animal cells was not possible, and that the chloroplasts would not survive or function.
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Scooped by
Ed Rybicki
October 31, 2024 11:07 AM
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Chronic Hepatitis B Virus (HBV) infection remains a significant public health concern, particularly in Africa, where the burden is substantial. HBV is an enveloped virus, classified into ten phylogenetically distinct genotypes (A–J).
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Scooped by
Ed Rybicki
October 31, 2024 11:06 AM
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Scooped by
Ed Rybicki
October 23, 2024 9:44 AM
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New research finds that bursts of exercise, like cycling or HIIT workouts, can improve memory, attention, and other cognitive functions.
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Scooped by
Ed Rybicki
October 23, 2024 9:43 AM
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XEC has become the second most prevalent strain in the country, accounting for 1 in 10 cases.
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Scooped by
Ed Rybicki
October 23, 2024 9:42 AM
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Recombinant proteins are crucial in pharmaceutical and other industries. A production method uses plants as hosts in transient protein expression systems. Researchers at the University of Tsukuba developed a technique to increase recombinant protein expression in lettuce by inhibiting RNA-dependent RNA polymerase.
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Scooped by
Ed Rybicki
October 23, 2024 9:40 AM
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In October, our longtime grantee David Baker won the Nobel Prize in Chemistry for groundbreaking work in protein design. We wanted to take the opportunity to highlight his work and some of its practical applications, such as enabling better vaccines, that we have been supporting Baker and his...
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