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Scooped by
Ed Rybicki
January 19, 2023 6:04 AM
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Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!
"Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work.
Instructor review copies: click on this link. https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo
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Scooped by
Ed Rybicki
May 7, 8:08 AM
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Sudan virus (SUDV) outbreaks in Uganda created public health concerns due to a lack of approved vaccines. In this study, the authors develop a repRNA SUDV vaccine and demonstrate full protection of a single dose of this vaccine in a lethal SUDV guinea pig model.
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Scooped by
Ed Rybicki
May 7, 8:07 AM
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In this Review, Chen, Farzan and Choe discuss our current understanding of the structure and function of the SARS-CoV-2 spike protein, the molecular mechanism of viral entry and the emergence of new variants, as well as the implications of these insights for development of spike protein-related...
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Scooped by
Ed Rybicki
May 7, 8:07 AM
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Journal of Virology, Ahead of Print.
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Scooped by
Ed Rybicki
May 7, 8:04 AM
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USask researchers recently published a paper in Scientific Reports that identified a promising alternative for controlling infectious diseases such as swine dysentery. Porcine β-defensin 5, or pBD-5, is a host defense peptide (HDP) that may help to reduce the industry's reliance on antibiotics.
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Scooped by
Ed Rybicki
May 7, 8:02 AM
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President Trump issued an executive order on Monday, banning federal funding for gain-of-function (GoF) research in “countries of concern" like China.
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Scooped by
Ed Rybicki
May 7, 8:01 AM
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European Journal of Medicinal Chemistry; 07/05/2025(AN 184827373); ISSN: 02235234Academic Search Premier
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Scooped by
Ed Rybicki
April 30, 7:09 AM
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The relationship among timing and severity of COVID-19 during pregnancy, placental pathology, and adverse pregnancy outcomes is not well understood. A prospective cohort study of 497 pregnant patients with COVID-19 whose placentas underwent systematic pathologic examination was conducted. The main exposure was timing of COVID-19 during pregnancy (first/second versus third trimester). The primary outcome was composite placental pathology that included high grade maternal vascular malperfusion or greater than 25 percent perivillous fibrin deposition.
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Scooped by
Ed Rybicki
April 30, 7:08 AM
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Today, the Global Virus Network (GVN), representing eminent human and animal virologists from 80+ Centers of Excellence and Affiliates in 40+ countries, published a comprehensive analysis and call-to-action in The Lancet Regional Health-Americas on the North American avian influenza virus, or...
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Scooped by
Ed Rybicki
April 30, 7:07 AM
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The organisms that cause infectious diseases that laboratories must report, and how to report them.
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Scooped by
Ed Rybicki
April 30, 7:05 AM
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The contribution of pre-existing conditions to severe versus mild postacute sequelae (PASC) of SARS-CoV-2 in the population is lacking. Here, we evaluated reproductive and other PASC side-by-side in unvaccinated and vaccinated individuals after 1st SARS-CoV-2 infection.
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Scooped by
Ed Rybicki
April 30, 7:04 AM
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Novel Mpro inhibitors exhibit broad activity against SARS-CoV-2 and other coronaviruses.
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Scooped by
Ed Rybicki
March 26, 4:50 AM
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Deep below Earth's surface, rock and mineral formations lay hidden with a secret brilliance. Under a black light, the chemicals fossilized within shine in brilliant hues of pink, blue and green. Scientists are using these fluorescent features to understand how the caves formed and how life is supported in extreme environments, which may reveal how life could persist in faraway places, like Jupiter's icy moon Europa.
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Scooped by
Ed Rybicki
May 7, 8:08 AM
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The rapid deployment of mRNA vaccines for SARS-CoV-2, such as BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna), provided a critical tool in combatin…...
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Scooped by
Ed Rybicki
May 7, 8:08 AM
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The burden of herpes simplex virus (HSV) infection is exacerbated due to the emergence of antiviral drug resistance and a lack of effective antibodies. Here the authors construct a bispecific nanobody that blocks receptor binding and prevents gD-gH/gL interaction, and show that it protects against...
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Scooped by
Ed Rybicki
May 7, 8:07 AM
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Researchers used AI models to design antibodies that neutralize over 1,300 SARS-CoV-2 strains, including Delta and Omicron. The models demonstrated faster, cheaper, and more adaptable therapeutic development compared to traditional methods.
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Scooped by
Ed Rybicki
May 7, 8:04 AM
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Ribonucleic acid (RNA) molecules may be best known for their job ferrying the genetic information encoded in DNA to a cell's protein factories, but these molecules aren't just a middleman for protein production. In fact, some RNA molecules don't code for proteins at all and serve various other important functions in cells, such as regulating gene expression and catalyzing chemical reactions. However, the functions of many non-coding RNAs remain mysterious.
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Scooped by
Ed Rybicki
May 7, 8:03 AM
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Exactly 100 years ago, famed Austrian physicist Erwin Schrödinger (yes, the cat guy) postulated his eponymous equation that explains how particles in quantum physics behave. A key component of quantum mechanics, Schrödinger's Equation provides a way to calculate the wave function of a system and how it changes dynamically in time.
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Scooped by
Ed Rybicki
May 7, 8:02 AM
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Patients suffering from long COVID may exhibit persistent inflammation in the heart and lungs for up to a year following SARS-CoV-2 infection-even when standard medical tests return normal results-potentially placing them at elevated risk for future cardiac and pulmonary conditions.
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Scooped by
Ed Rybicki
May 7, 8:01 AM
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This research provides a comprehensive review of aptamer-based strategies that target SARS-CoV-2, offering a promising avenue for blocking the virus. Behind this groundbreaking paper lies a tale of collaboration across borders, and a quest for the most comprehensive aptamer summary ever compiled.
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Scooped by
Ed Rybicki
April 30, 7:08 AM
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Delivering functional proteins or protein complexes into cells continues to be a significant challenge. Here, the authors develop efficient systems by using engineered extracellular vesicles to deliver functional cargoes, including CRISPR/Cas9-ribonucleoproteins, both in vitro and in vivo.
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Scooped by
Ed Rybicki
April 30, 7:08 AM
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Pope Francis’ health crisis highlights the delicate balance between transparency and privacy, particularly if COVID-19 had been involved and the global reaction it could have provoked.
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Scooped by
Ed Rybicki
April 30, 7:06 AM
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Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new computational method for exploring DNA sequence patterns. The method, called KMAP, enables intuitive visualization of short DNA sequences and helps reveal how regulatory elements behave in different biological contexts. The study was recently published in Genome Research.
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Scooped by
Ed Rybicki
April 30, 7:05 AM
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Tetanus-diphtheriaa-acellular pertussis–inactivated polio virus vaccination during pregnancy is safe and boosts pertussis-specific antibody responses in infants.
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Scooped by
Ed Rybicki
April 30, 7:04 AM
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Kennedy's early moves as HHS chief suggest he may intervene on vaccine policy, with Novavax, mRNA shots, and pediatric Covid immunizations.
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Scooped by
Ed Rybicki
March 26, 4:48 AM
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A new study reveals plants, fungi, bacteria, protists, and even some viruses deploy venom-like mechanisms, similar to that of venomous snakes, scorpions and spiders, according to researchers at Loma Linda University School of Medicine.
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Scoop.it!
!["Circovirus kills dogs [in USA] in days, no vaccine": disinformation spreads.... | Virology News | Scoop.it](https://img.scoop.it/vLl-Gyo6RfQWv_hTDRC-EDl72eJkfbmt4t8yenImKBVvK0kTmF0xjctABnaLJIm9)
This is a highly misleading report in a national US daily: basically, it is calimed that "circovirus" is spreading across the USA, killing dogs.
At one point in the USA Today clip, they claim that "...the virus originates in pigs and birds, and has mutated...".
Really?? The VERY distinct circoviruses that infect pigs - two kinds, both called PCV, only one nasty - and birds (MANY kinds) have spread to dogs??
This is, of course, complete nonsense: the only reports of actual virus sequences - see here (http://jvi.asm.org/content/86/12/7018.full) and here (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647419/) - showed that there was a distinct circovirus (capsid and replicase proteins share <25% and <50% identities, respectively, with those of the known animal circoviruses), and that isolates from different dogs had very similar viruses. Thus, a hitherto undiscovered circovirus that is distinct from any previously characterised agent, is infecting dogs in the USA.
But is is NOT known to what extent. That still needs some work! Meantime, USAToday: get your science right!!