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May 13, 2013 4:18 AM
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New vaccines needed for pathogens infecting animals and humans: One Health – Dr. Thomas P. Monath

New vaccines needed for pathogens infecting animals and humans: One Health – Dr. Thomas P. Monath | Virology News | Scoop.it
World Vaccine Congress & Expo 2013 

Dr Thomas P. Monath, Adjunct Professor at Harvard School of Public Health gives his presentation on ‘New vaccines needed for pathogens infecting animals and humans: One Health’.

 

Ed Rybicki's insight:

This is a very interesting presentation for a number of reasons - prime among which is the fact that a number of very influential international organisations and funders are taking the notion of "One Health" very seriously.

 

That is, the development of reagents and vaccines that can be used for agents that cause both animal and human diseases, such as avian influenza, Nipah and Hendra and Rift Valley fever viruses, and so on.

 

Great idea - and one we are trying to address with making such things in plants!

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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January 19, 2023 6:04 AM
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Cann's Principles of Molecular Virology - 7th Edition

Cann's Principles of Molecular Virology - 7th Edition | Virology News | Scoop.it

Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!


Instructor review copies: click on this link.

https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo

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March 26, 4:48 AM
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Overlooked diversity: New research suggests plants, fungi and even viruses use venom

A new study reveals plants, fungi, bacteria, protists, and even some viruses deploy venom-like mechanisms, similar to that of venomous snakes, scorpions and spiders, according to researchers at Loma Linda University School of Medicine.
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March 26, 4:46 AM
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Gas hunt may reveal signs of alien life on distant planets

Gas hunt may reveal signs of alien life on distant planets | Virology News | Scoop.it
Researchers have identified a promising new way to detect alien life on faraway planets.
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March 26, 4:40 AM
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H5N1 Bird Flu Mutates to Better Hijack Human Cells, New UNC Charlotte Study Shows

H5N1 Bird Flu Mutates to Better Hijack Human Cells, New UNC Charlotte Study Shows | Virology News | Scoop.it
The latest CIPHER research on H5N1 viral lineages could have major implications for vaccine development.
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March 25, 9:07 AM
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Computational model compares mpox's airborne transmission risk to COVID-19 and smallpox

A collaborative research effort between the A*STAR Infectious Diseases Labs (A*STAR IDL) and the A*STAR Institute of High Performance Computing (A*STAR IHPC) has provided new insights into the likelihood of mpox spreading by airborne respiratory particles, comparing it to SARS-CoV-2 and smallpox.
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March 25, 9:05 AM
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Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25 | Nature Communications

Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25 | Nature Communications | Virology News | Scoop.it
This study provides the structural and biochemical characterization of the RSV NS1/MED25 ACID complex, revealing how RSV exploits fuzzy interfaces between coactivators and transcription factors, including ATF3, to modulate host gene transcription.
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March 25, 9:05 AM
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Persistent mortality in critical COVID-19 ICU cases from wild-type to delta variant: A descriptive cohort study | Scientific Reports

Persistent mortality in critical COVID-19 ICU cases from wild-type to delta variant: A descriptive cohort study | Scientific Reports | Virology News | Scoop.it
The SARS-CoV-2 pandemic led to significant advancements in treatment and vaccination, contributing to a decline in overall COVID-19-related mortality. However, it remains unclear whether the mortality rate for critical cases treated on intensive care units has also decreased.
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March 25, 9:04 AM
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Image: Hubble captures the Small Magellanic Cloud

Say hello to one of the Milky Way's neighbors! This NASA/ESA Hubble Space Telescope image features a scene from one of the closest galaxies to the Milky Way, the Small Magellanic Cloud (SMC). The SMC is a dwarf galaxy located about 200,000 light-years away. Most of the galaxy resides in the constellation Tucana, but a small section crosses over into the neighboring constellation Hydrus.
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March 12, 4:32 AM
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High Rates Of Respiratory Virus Co-Detection Found Among Children

High Rates Of Respiratory Virus Co-Detection Found Among Children | Virology News | Scoop.it
New research highlighting the respiratory health of children during the SARS-CoV-2 pandemic has unveiled concerning trends: high rates of co-detected respiratory…...
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March 12, 4:32 AM
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A Coupled Model of the Cardiovascular and Immune Systems to Analyze the Effects of COVID-19 Infection

A Coupled Model of the Cardiovascular and Immune Systems to Analyze the Effects of COVID-19 Infection | Virology News | Scoop.it
The COVID-19 pandemic has underscored the importance of understanding the interplay between the cardiovascular and immune systems during viral infections. SARS-CoV-2 enters human cells via the ACE-2 enzyme, initiating a cascade of immune responses.
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February 18, 8:36 AM
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Antigen-presenting innate lymphoid cells induced by BCG vaccination promote a respiratory antiviral immune response through the skin‒lung axis | Cellular & Molecular Immunology

Antigen-presenting innate lymphoid cells induced by BCG vaccination promote a respiratory antiviral immune response through the skin‒lung axis | Cellular & Molecular Immunology | Virology News | Scoop.it
The route of vaccine administration is associated with various immune outcomes, and the relationship between the route of administration and broad protection against heterologous pathogens remains unclear.
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February 18, 8:33 AM
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New Strategy Identifies Superior Pathogen Variants

New Strategy Identifies Superior Pathogen Variants | Virology News | Scoop.it
A simple model projected which strains were likely to be highly transmissible, with implications for public health.
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February 17, 7:41 AM
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Predicting Antibody Affinity Changes upon Mutation Based on Unbound Protein Structures

Antibodies are key proteins in the immune system that can reversibly and non-covalently bind specifically to their corresponding antigens, forming antigen-antibody complexes. They play a crucial role in recognizing foreign or self-antigens during the adaptive immune response.
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March 26, 4:50 AM
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Fluorescent caves could explain how life persists in extraterrestrial environments

Deep below Earth's surface, rock and mineral formations lay hidden with a secret brilliance. Under a black light, the chemicals fossilized within shine in brilliant hues of pink, blue and green. Scientists are using these fluorescent features to understand how the caves formed and how life is supported in extreme environments, which may reveal how life could persist in faraway places, like Jupiter's icy moon Europa.
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March 26, 4:47 AM
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Japanese scientists pioneer nonviral gene delivery in primates

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a transgene—that is, a gene that has been artificially inserted into an organism—into cynomolgus monkeys, which is a species of primate closely related to humans. The paper is published in the journal Nature Communications.
Ed Rybicki's insight:
Interesting: we used PiggyBac to get transgenic insect cells for HIV Env expression; should have realised it could be used more widely!
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March 26, 4:45 AM
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DNA-loaded lipid nanoparticles are poised to bring gene therapy to common chronic diseases

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.
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March 26, 4:39 AM
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Tadpoles try to flee dangerous virus in their pond by growing much faster than normal, research shows

The world's amphibians are in trouble. Because of their sensitivity to climate change, habitat loss, and pollution, they may be the canary in the coal mine for the nascent anthropogenic mass extinction. Approximately 200 amphibian species have become extinct since the 1970s, and the International Union for the Conservation of Nature estimates that 34% of the 7,296 known remaining species are likewise at risk.
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March 25, 9:07 AM
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What rules actually prohibit us from building a warp drive?

In 1994, Miguel Alcubierre was able to construct a valid solution to the equations of general relativity that enable a warp drive. But now we need to tackle the rest of relativity: How do we arrange matter and energy to make that particular configuration of spacetime possible?
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March 25, 9:05 AM
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Lengthy delays in H5N1 genome submissions to GISAID | Nature Biotechnology

Lengthy delays in H5N1 genome submissions to GISAID | Nature Biotechnology | Virology News | Scoop.it
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March 25, 9:04 AM
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‘Low-sugar’ vaccine can provide broad immunity against coronavirus variants | Newswise

‘Low-sugar’ vaccine can provide broad immunity against coronavirus variants | Newswise | Virology News | Scoop.it
A single vaccine could protect animal models from coronaviruses that cause COVID-19 and the flu. It works by creating antibodies that remove the virus’ protective sugar coat and target a rarely mutating region of the spike protein.
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March 12, 5:37 AM
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Five years of COVID-19 underscore value of coordinated efforts to manage disease

Five years ago, on March 11, 2020, the World Health Organization declared the outbreak of COVID-19 a global pandemic. The novel coronavirus, dubbed SARS-CoV-2, began as a "cluster of severe pneumonia cases of unknown cause" reported in Wuhan, China, in December 2019. It had spread to 118,000 cases reported in 114 countries by March 11.
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March 12, 4:32 AM
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President Trump Should Reinstate President Obama’s Moratorium on Risky Biological Research

President Trump Should Reinstate President Obama’s Moratorium on Risky Biological Research | Virology News | Scoop.it
President Trump is reportedly preparing an executive order to halt funding of risky viral gain-of-function research—lab experimentation designed to genetically manipulate biological agents to make them more transmissible and pathogenic.
Ed Rybicki's insight:
Warning: bullsh1t alert!! But bullsh1t that's being used to influence an idiot into messing with virology.
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March 12, 4:31 AM
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Progress on Respiratory Syncytial Virus Vaccine Development and Evaluation Methods

Progress on Respiratory Syncytial Virus Vaccine Development and Evaluation Methods | Virology News | Scoop.it
Respiratory syncytial virus (RSV) remains a significant global health threat, especially to infants, the elderly, and immunocompromised individuals. This review comprehensively explores the progress in RSV vaccine development, the immune evaluation methods, and immunological surrogate.
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February 18, 8:35 AM
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Researchers overlooked airborne diseases for centuries — then COVID-19 changed everything

Researchers overlooked airborne diseases for centuries — then COVID-19 changed everything | Virology News | Scoop.it
A fascinating exploration of microbes that can travel through the air reveals how the pandemic marked a turning point for a crucial research field.
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February 18, 8:33 AM
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Global Variations in SARS-CoV-2 Secondary Attack Rates

Global Variations in SARS-CoV-2 Secondary Attack Rates | Virology News | Scoop.it
The following is a summary of “Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis,” published in the February 2025 issue of BMC Infectious Diseases by Sumsuzzman et al.
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February 17, 7:40 AM
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CRISPR system variant shows a novel DNA cleavage mechanism

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.
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