Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!
"Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work.
A research team at CiQUS (University of Santiago de Compostela, Spain) has unveiled an innovative molecular approach that enables anticancer drugs to reach the nucleus of tumor cells, where they can exert their therapeutic effect. The study focused on doxorubicin, a widely used chemotherapy agent. Prolonged exposure to this drug often leads to the emergence of resistant cells, a major clinical challenge that this strategy successfully overcomes while preserving the drug's antitumor activity.
In the ever-evolving realm of therapeutic development, humanization of monoclonal antibodies and nanobodies is an essential step that significantly enhances their clinical applicability.The process aims to modify these proteins derived from non-human species to resemble their human counterparts more...
This video explores how COVID-19 infection alters the oral and gut microbiota and how these microbial changes correlate with SARS-CoV-2 viral load during hospitalization. The study provides deep insight into the microbial dysbiosis observed in infected patients and its potential impact on disease severity, immune response, and recovery. By linking oral–gut microbial networks with viral persistence, this research opens new perspectives for microbiome-based diagnostics and therapeutic interventions in infectious diseases.
Klein and colleagues characterize 04_A06, a new VH1-2-encoded broadly neutralizing antibody that has marked breadth and potency against extended multiclade HIV-1 pseudovirus panels and can maintain full viral suppression in HIV-1-infected humanized mice.
In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using computers to accurately predict the 3D structure of any given amino acid sequence.
In an illuminating new study published in Nature Communications, researchers report groundbreaking insights into the immune responses against COVID-19 among people living with HIV.The work, emerging from the CoVPN 3008 study, identifies neutralizing and binding antibodies as critical correlates of...
Imagine tiny machines, smaller than a virus, spinning inside cancer cells and rewiring their behavior from within. No surgery, no harsh chemicals, just precision at the molecular level.
Inside nearly every cell of your body, the tiny F1 motor works non-stop to create adenosine triphosphate (ATP), the universal energy source that powers almost every action you take—from breathing to running. While scientists have understood the structure of this molecular machine for years, a key mystery remained: how does its partner, the F0 motor, spin F1 with maximum efficiency?
Interstellar visitor 3I/ATLAS has been constantly changing as it makes its way through our solar system. That's to be expected, as, for the first time in potentially billions of years, it's getting close to the energy put out by a star.
Spanish authorities on Monday announced a cull of animals infected in the country's first outbreak of highly contagious lumpy skin disease, which has struck cattle on a farm.
In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.
The risk of developing long-term symptoms after a COVID-19 infection has dropped sharply in the Netherlands, according to new research by the RIVM. The study shows that people infected with SARS-CoV-2 in 2023 were no more likely to report persistent health problems than people who never caught the...
A cell can act in astonishingly complex ways. It must decide for itself whether to grow and multiply, rest, specialize, age or die. This applies just as much to mammalian cells as it does to seemingly simple microbes.
The COVID-19 pandemic has profoundly altered various aspects of healthcare delivery and disease epidemiology, with childhood asthma and wheezing disorders presenting a uniquely compelling case study within this transformative dynamic.
Our group has previously reported on (E)-4-(1-(2-(5-(4-chlorophenyl)thiazol-2-yl)hydrazono)ethyl)phenol (3a) as an antiviral agent against DENV with a…...
Viral diseases cause significant economic losses within the equine population. Horses are susceptible to equine coronavirus (ECoV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), although only ECoV has been associated to clinical disease.
Broad-spectrum antiviral agent (BSAA) drugs are essential in the fight against viral, especially emerging, diseases.However, their development faces …...
A world-first study has proven microbes essential for human health can survive the extreme forces of space launch. The study has been published in npj Microgravity.
Recently, NASA revealed exciting details of new findings from Mars. Scientists have discovered tiny patterns of unusual minerals in the clay-rich rocks on the edge of Jezero Crater—an ancient lake once fed by Martian river systems, and the exploration site of the NASA Perseverance Rover.
Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in simple, well-studied bacteria like Escherichia coli (better known as E. coli), about one-quarter of the genes have no known function. Traditional approaches—turning off one gene at a time and studying the effects—are slow, laborious, and sometimes inconclusive due to gene redundancy.
In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.
When astronauts returned from NASA's final Apollo moon mission in 1972, some of the samples they collected were sealed and carefully stored away in the hope that future researchers using advanced equipment might analyze them and make new discoveries.
Researchers in Japan have pinpointed a biological cause of Long COVID brain fog using advanced PET brain imaging. They discovered widespread increases in AMPA receptor density linked to cognitive impairment and inflammation.
/PRNewswire/ -- Novavax, Inc. (Nasdaq: NVAX) has completed the transfer of the marketing authorization for its COVID-19 vaccine, Nuvaxovid® to Sanofi, in the...
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