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Protalix Soars on FDA Approval of Gaucher Drug: Tel Aviv Mover

Protalix Soars on FDA Approval of Gaucher Drug: Tel Aviv Mover | Virology News | Scoop.it

"Protalix BioTherapeutics Inc. soared in Tel Aviv trading after the biopharmaceutical company’s first product won approval from the U.S. Food and Drug Administration.

Protalix expects approval to sell its Gaucher disease drug in Israel soon, Aviezer said. Israel has at least 500 patients affected with the illness, he said. The company also is awaiting a regulatory decision in the European Union.
“This is a biotechnology milestone as it it the first time the FDA has approved a product that was engineered in plant cells, as opposed to mammalian or bacterial-based systems,” Yoav Kedar, a biotechnology consultant for Clal Finance Brokerage Ltd., said in an interview. “The approval will better position the company to receive approvals in Europe, Israel and Brazil.”
Gaucher disease can cause fat to build up in the liver, spleen, bone marrow and nervous system. About 1 in 14 individuals of Ashkenazi Jewish ancestry carries the mutated gene that can cause the illness, and as many as 1 in 500 present a form of the disorder."

 

This is a seriously big deal, and I have blogged on it here before: this is a plant-made bio-better, now licenced for human use as a therapeutic for a nasty genetic disease.  It should compete well, given that other offerings are made in mammalian cells - and one manufacturer's output was recently shut down completely due to a viral infection of their cell cultures, which is what led to accelerated approval for Protalix's product.

 

Going green...you know the rest.  I thank Russell Kightley Media for the plant cell graphic

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
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Brazil suspends use of AstraZeneca vaccine in pregnant women nationally after death

Brazil suspends use of AstraZeneca vaccine in pregnant women nationally after death | Virology News | Scoop.it
Brazil's federal government on Tuesday nationally suspended the vaccination of pregnant women with the AstraZeneca (AZN.L) COVID-19 shot, after an expectant mother in Rio de Janeiro died from a stroke possibly related to the inoculation.
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COVID-19 may alter gray matter in the brain

COVID-19 may alter gray matter in the brain | Virology News | Scoop.it
Research in patients who had COVID-19 shows those who received oxygen therapy or had fever show less gray matter in part of the brain.
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Porcine circovirus 3 – is it a virus to worry about? –

Porcine circovirus 3 – is it a virus to worry about? – | Virology News | Scoop.it
Porcine circovirus 2 (PCV2) is well-known in the swine industry, but is there reason to worry about its cousin PCV3?
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South African vaccine cheaters outed

South African vaccine cheaters outed | Virology News | Scoop.it
The country might not be in the grips of a third wave just yet but the COVID situation remains grim. All provinces have recorded a surge in infections with the Northern Cape and North West cited as provinces of particular concern.
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EXPLAINER: Why Japan has been slow to roll out vaccinations

EXPLAINER: Why Japan has been slow to roll out vaccinations | Virology News | Scoop.it
TOKYO (AP) — Japan's rollout of COVID-19 vaccines began belatedly in mid-February, months behind the United States and many other countries. Officials blamed a shortage of Pfizer Inc. vaccine from Europe as the main culprit in the delay.
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Influenza A virus defective viral genomes are inefficiently packaged into virions relative to wild-type genomic RNAs

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution...
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How South Africa’s Covid-19 vaccination programme compares to other countries

How South Africa’s Covid-19 vaccination programme compares to other countries | Virology News | Scoop.it
Out of 168 countries that have begun administering the Covid-19 vaccine, South Africa places 79 on the list as of April 5 - after vaccinating just 0.5% of the population...
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India approves Russia's Sputnik V COVID-19 vaccine | Reuters

India approves Russia's Sputnik V COVID-19 vaccine | Reuters | Virology News | Scoop.it
India has approved the use of Russian Sputnik V COVID-19 vaccine, the Russian Direct Investment Fund (RDIF) said on Monday, confirming earlier reports of its imminent endorsement.
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Relic: Iron Lung

Relic: Iron Lung | Virology News | Scoop.it
During the COVID-19 pandemic, technology has had to advance at rates never seen before.One of the first big leaps in technology followed the flu pandemic...
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Bird flu outbreak confirmed in SA, Joburg farm quarantined

Bird flu outbreak confirmed in SA, Joburg farm quarantined | Virology News | Scoop.it
The poultry industry was on high alert on Tuesday after an outbreak of avian influenza was confirmed in a commercial layer flock on the East Rand of Johannesburg.
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Cocoa powder eases liver disease in mice

Cocoa powder eases liver disease in mice | Virology News | Scoop.it
Cocoa powder added to the diet of obese mice markedly reduced the severity of liver disease. Researchers suggest the findings have implications for people.
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Africa CDC says cannot predict when second Covid-19 shots will arrive

Africa CDC says cannot predict when second Covid-19 shots will arrive | Virology News | Scoop.it
Many Africans who have received their first Covid-19 vaccine do not know when they will get a second shot because deliveries are delayed, the continent's top public health official said on Thursday.
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Vast majority of young people want the COVID vax

Vast majority of young people want the COVID vax | Virology News | Scoop.it
New poll results find that the vast majority of teenagers and young adults want to get the COVID-19 vaccine or have already.
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5 Reasons To Wear A Face Mask Other Than Covid-19 | The Out Door Wear

5 Reasons To Wear A Face Mask Other Than Covid-19 | The Out Door Wear | Virology News | Scoop.it
Those face masks that everyone has been wearing might be doing more than just keeping us safe from possibly contracting the disease COVID-19...
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Explained: When corpses of influenza victims were dumped in Narmada river in 1918

Explained: When corpses of influenza victims were dumped in Narmada river in 1918 | Virology News | Scoop.it
Here is the official report from 1918, sourced from the National Archives, which sheds more light on what happened.
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Plant DNA polymerases α and δ mediate replication of geminiviruses

Plant DNA polymerases α and δ mediate replication of geminiviruses | Virology News | Scoop.it
Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.
Ed Rybicki's insight:
Hm. And if the virus doesn't HAVE a C3 protein? Because mastreviruses don't for example?
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L.A. Times owner pledges $213 million for COVID-19 vaccine work in South Africa

L.A. Times owner pledges $213 million for COVID-19 vaccine work in South Africa | Virology News | Scoop.it
Patrick Soon-Shiong will give $213 million to South Africa, the country of his birth, to help with the transfer of new COVID-19 vaccine technology.
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Can cannabis ease chronic itch?

Can cannabis ease chronic itch? | Virology News | Scoop.it
Cannabis may offer rapid relief from chronic itch, an unrelenting and at times debilitating condtion.
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Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors | Virology News | Scoop.it
Investigation of the human antibody response to influenza virus infection has been largely limited to serology, with relatively little analysis at the molecular level. The 1918 H1N1 influenza virus pandemic was the most severe of the modern era.
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Flu may play part in plaque-rupturing heart attacks

Flu may play part in plaque-rupturing heart attacks | Virology News | Scoop.it
Getting a flu vaccine can reduce the risk of a common type of heart attack in people 60 and older, according to new research that suggests the virus plays a role in rupturing plaque.
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IL‐1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection 

IL‐1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection  | Virology News | Scoop.it
Abstract Hyperinflammatory responses including the production of NLRP3‐dependent IL‐1β is a characteristic feature of severe and fatal influenza A virus (IAV) infections. The NLRP3 inflammasome has...
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Why South Africans should get the flu vaccine now to help the fight against Covid-19

Why South Africans should get the flu vaccine now to help the fight against Covid-19 | Virology News | Scoop.it
The regular flu vaccine won't stop the novel coronavirus – but it can prevent confusion from similar symptoms.
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Can One Receive the Covid-19 Vaccine While Fasting? – Guidance from the Caliph

Can One Receive the Covid-19 Vaccine While Fasting? – Guidance from the Caliph | Virology News | Scoop.it
For Muslims all over the world, Ramadan is the most blessed month of the year.As Muslims prepare to fast from dawn till dusk every day for a month, whilst striving to improve and strengthen their relationship with God Almighty, this year, the blessed month of Ramadan comes once again, in the midst...
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Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract 

Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract infections that produce a wide spectrum of clinical disease severity in humans. The novel betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has since...
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Discovery could lead to Duchenne muscular dystrophy therapies

Discovery could lead to Duchenne muscular dystrophy therapies | Virology News | Scoop.it
Research into how chronic inflammation promotes muscle fibrosis could lead to new therapies for people with Duchenne muscular dystrophy, a fatal disease.
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