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Life is a programming language, and molecular biologist Andrew Hessel thinks that it will be increasingly available to anyone interested in designing with the building blocks of life. 
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The Living's (Buildings that grow? @autodesk acquires The Living & bets on synthetic biology. #synthbio #theliving http://t.co/KmuQCZyZJK)
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Synthetic Biology: Volume 1 (Specialist Periodical Reports) [Maxim Ryadnov, Luc Brunsveld, Hiroaki Suga, Eric Kool, Birger Lindberg Moller, Alexander Kros, Cristiano Chiarabelli, Stephen Hart, Maarten Merkx, Oliver Rackham, S Tekeuchi, Paul Dalby, Jeroen Cornelissen] on Amazon.com. *FREE* shipping on qualifying offers. Synthetic biology is a new area of biological research that combines science and engineering in order to design and build novel biological functions and systems. The definition of synthetic biology has been generally accepted as the engineering of biology: the synthesis of complex
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The latest generation of DNA sequencers allows all the genes of a plant, as well as any pathogens present, to be charted literally within a few days. “This provides unprecedented opportunities for the diagnosis of plant diseases, as well as, for example, identifying and tracking new disease outbreaks,” says Dr Theo van der Lee, senior scientist at the Department of Bio-Interactions and Plant Health at Plant Research International. “We can now detect pathogens directly from infected plant material, usually without having to guess in advance which bacterium, fungus or virus is the culprit.”
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An awesome new #synbio community page by PLOS http://bit.ly/1lzSlzL
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Synthetic Biology Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast,2013 - 2019
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With advances in biological and genomic sciences accelerating at an ever-increasing pace, what does the future hold? If biological progress is indeed advancing more rapidly than Moore’s Law, as many assert, what are the economic and societal implications? In this video from our June 17 Techonomy Bio conference, Alex Lash, biotech editor at Xconomy, interviews Drew Endy, bioengineer at Stanford, about biological processes.
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CRISPR-based transcriptional activators and repressors for synthetic circuits.
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By Erin Brodwin Bio-hacking has come a long way since a handful of science geeks began playing with bacterial DNA in their basements in the 2000s. Today, the products of do-it-yourself biology come out of closet laboratories and into the hands—or backyards—of consumers. It is the era of crowdsourced science, in which almost anyone can make a new creature. Last year, a team of entrepreneurs created a glow-in-the-dark plant engineered with genes from bioluminescent bacteria; this year, a college undergrad in Brooklyn is working to create plants that would survive an enormous dose of radiation and help clean up nuclear disasters or even colonize another planet. At a communal table just outside of a glass-walled laboratory at Genspace, a woman greets me, introduces herself as Ellen Jorgensen and hands me a cotton swab. She tells me to rub the inside of my cheek with the swab. In the course of a few days, Jorgensen explains, I’ll open up my cells and find out what secrets lie inside my genes. Each of these cells contains everything from my ancestors’ migration story to my susceptibility to certain diseases....."
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PLOS Computational Biology is an open-access
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Synthetic biology opens new doors on what life can be, and do. How will we utilize the awesome new tools at our disposal? In this video from our June 17 Techonomy Bio conference, Andrew Hessel of Autodesk moderates a discussion with Ellen Jorgensen of Genspace and Ryan Phelan of Revive & Restore.
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by Angel Goñi-Moreno, Martyn Amos, Fernando de la Cruz
"Recent efforts in synthetic biology have focussed on the implementation of logical functions within living cells. One aim is to facilitate both internal “re-programming” and external control of cells, with potential applications in a wide range of domains. However, fundamental limitations on the degree to which single cells may be re-engineered have led to a growth of interest in multicellular systems, in which a “computation” is distributed over a number of different cell types, in a manner analogous to modern computer networks. Within this model, individual cell type perform specific sub-tasks, the results of which are then communicated to other cell types for further processing. The manner in which outputs are communicated is therefore of great significance to the overall success of such a scheme. Previous experiments in distributed cellular computation have used global communication schemes, such as quorum sensing (QS), to implement the “wiring” between cell types. While useful, this method lacks specificity, and limits the amount of information that may be transferred at any one time. We propose an alternative scheme, based on specific cell-cell conjugation. This mechanism allows for the direct transfer of genetic information between bacteria, via circular DNA strands known as plasmids. We design a multi-cellular population that is able to compute, in a distributed fashion, a Boolean XOR function. Through this, we describe a general scheme for distributed logic that works by mixing different strains in a single population; this constitutes an important advantage of our novel approach. Importantly, the amount of genetic information exchanged through conjugation is significantly higher than the amount possible through QS-based communication. We provide full computational modelling and simulation results, using deterministic, stochastic and spatially-explicit methods. These simulations explore the behaviour of one possible conjugation-wired cellular computing system under different conditions, and provide baseline information for future laboratory implementations."
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by Minsu Kim Minsu Kim's Living Food project builds on developments in synthetic biology to propose meals that behave like living creatures.
"Synthetic biotech has already started to create artificial life in organic forms," says the designer, citing a swimming artificial jellyfish made of heart cells by researchers at Caltech and Harvard University. "Breathing life into artificial digestible forms in not merely a fantasy." In the Design Interactions department of the Royal College of Art's graduate exhibition this week Minsu Kim presents three dishes, each exhibiting a different behaviour: wriggling around, waving tentacles or puffing up as though breathing. "This project explores new culinary experiences through developments in synthetic biology, and finds its lineage in haute cuisine and molecular gastronomy," the designer adds. "What if food was able to play with our cutlery and create hyper-sensations in our mouth?" Show RCA continues until 30 June 2013. Other projects on show include glassware that creates kaleidoscopic effects and bicycle helmets made of pulped newspaper. Other stories about futuristic food on Dezeen include treats with edible packaging, fruit labelled with lasers and 3D-printed hamburgers. Find out how soon we could be tucking into 3D-printed steaks in an extract from Print Shift, our one-off print-on-demand publication all about 3D printing......"
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by Drew Endy, a Stanford professor who is one of the world’s leaders in synthetic biology, on stage called the event “awesome” and said he had never seen such a collection of people in one place. “People in other sectors of technology simply don’t know very much about biology and biology’s economic impact,” he continued. And like literally every expert at the event, he was supremely optimistic about the future potential of life sciences for society: “The biotech that exists right now is sort of the snowflake on the tip of the iceberg. There’s so much more to make.” Endy is a passionate advocate of open-source access to biological discoveries and tools to further accelerate progress by widening the community of researchers and innovators beyond just big companies. Synthetic biology was a centerpiece of the conference, which aimed particularly to examine how progress in IT was stimulating an acceleration in biological discovery. Andrew Hessel of software-maker Autodesk crisply defined synthetic biology, calling it “genetic engineering done with digital tools.” He added: “This makes it faster, cheaper, and easier to do.” Hessel wants to use the plummeting cost of DNA sequencing—another central technology in our discussions—to enable individually-customized cancer drugs. He explained how it could happen soon...."
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Open source, open science, open data, open access, open education, open learning -- this course provides an introduction to the important concept of openness from a variety of perspectives, including education, publishing, librarianship, economics, politics, and more, and asks you to discover what it means to you. Open Knowledge is international and multi-institutional, bringing together instructors and students from Canada, Ghana, Mexico, the United States, and the rest of the world. It will challenge you take control of your own education, to determine your own personal learning objectives, to contribute to the development of the curriculum, to reflect on your progress, to learn new digital skills, and to take a leadership role in the virtual classroom. It will also provide you with the opportunity to connect with colleagues from different countries and professions, and to better understand areas where your interests overlap and where unexpected distincts exist. We hope you’ll consider taking this journey with us.
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The story of programming prodigy and information activist Aaron Swartz. From Swartz's help in development of the basic internet protocol RSS to his co-founding of Reddit, his fingerprints are all over the internet. But it was Swartz's groundbreaking work in social justice and political organizing combined with his aggressive approach to information access that ensnared him in a two year legal battle with the Federal government. It was a battle that ended with the taking of his own life at the age of 26. Aaron's story touched a nerve with people far beyond the online communities in which he was a celebrity. This film is a personal story about what we lose when we are tone deaf about technology and its relationship to our civil liberties.
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Wyss Institute at Harvard (Our 2014 National Finalist Peng Yin from @wyssinstitute receives ACS Synthetic Biology Young Investigator Award http://t.co/orCxQ12v8o)...
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congratulations!
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