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A study led by researchers at The Saban Research Institute of Children's Hospital Los Angeles (CHLA) suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants. Their findings, reporte
Via Kenzibit
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Scooped by
Gilbert C FAURE
April 16, 2016 1:54 PM
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PLoS One. 2015 Apr 20;10(4):e0124659. doi: 10.1371/journal.pone.0124659. eCollection 2015. Research Support, Non-U.S. Gov't
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Scooped by
Gilbert C FAURE
April 16, 2016 3:05 AM
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PLoS One. 2016 Apr 14;11(4):e0153045. doi: 10.1371/journal.pone.0153045.
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Suggested by
Société Francaise d'Immunologie
March 6, 2016 2:46 PM
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Live attenuated vaccines such as SIV with a deleted nef gene have provided the most robust protection against subsequent vaginal challenge with wild-type (WT) SIV in the SIV–rhesus macaque model of HIV-1 transmission to women.
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Scooped by
Gilbert C FAURE
February 3, 2016 12:24 PM
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New research has revealed that a key immune system component -- innate lymphoid cells (ILC) -- is destroyed during acute HIV infection. This may play a key role in understanding the progression of the disease from HIV to AIDS.
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Scooped by
Gilbert C FAURE
January 24, 2016 11:54 AM
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Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Na https://t.co/WNbdOvEUrd
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Scooped by
Gilbert C FAURE
January 13, 2016 10:13 AM
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Mucosal Immunology is the official publication of the Society of Mucosal Immunology (SMI). It aims to provide a forum for both basic and clinical scientists to discuss all aspects of immunity and inflammation involving mucosal tissues. The journal reflects the interests of scientists studying gastrointestinal, pulmonary, nasopharyngeal, oral, ocular, and genitourinary immunology through the publication of original research articles, scholarly reviews, and timely commentaries, editorials and letters.
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Gilbert C FAURE
November 19, 2015 2:17 PM
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Publication date: Available online 11 November 2015 Source:Vaccine Author(s): Shubhanshi Trivedi, Teresa Neeman, Ronald J. Jackson, Roshanka Ranasinghe, Cameron Jack, Charani Ranasinghe Thirty gene...
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Rescooped by
Gilbert C FAURE
from Immune-Monitoring
September 10, 2015 5:41 AM
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Some individuals are resistant to HIV-1 infection despite repeated exposure to the virus, suggesting the presence of a complex antiviral response. Innate factors like IL-22 exert gut mucosal protection and polyfunctional T cells have been associated with low progression in HIV infection; therefore, we evaluated the frequencies of CD4+ and CD8+ T cell-secreting cytokines, including Tc22/Th22 cells and polyfunctional T cells in HIV-1-exposed uninfected individuals (EUs), their HIV-1-infected partners and healthy controls.
Via Marcelo de Carvalho Bittencourt
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Scooped by
Gilbert C FAURE
September 4, 2015 4:58 AM
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Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced ...
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Gilbert C FAURE
August 6, 2015 6:21 AM
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by Joe Geraghty, Alexander Thumbs, Anstead Kankwatira, Tim Andrews, Andrew Moore, Rose Malamba, Neema Mtunthama, Kai Hellberg, Lughano Kalongolera, Paul O’Toole, Andrea Varro, D.
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Gilbert C FAURE
July 11, 2015 1:35 AM
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by Derseree Archary, Lenine J. Liebenberg, Lise Werner, Sahil Tulsi, Nelisile Majola, Nivashnee Naicker, Sarah Dlamini, Thomas J. Hope, Natasha Samsunder, Salim S. Abdool Karim, Lynn Morris, Jo-Ann S.
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Gilbert C FAURE
May 24, 2015 3:51 PM
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The authors discuss the key scientific issues in mucosal and innate immunity related to immune protection against HIV infection.
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Scooped by
Gilbert C FAURE
May 3, 2016 3:08 PM
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Oral Dis. 2016 Apr;22 Suppl 1:171-80. doi: 10.1111/odi.12451.
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Scooped by
Gilbert C FAURE
April 16, 2016 3:30 AM
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AIDS Res Ther. 2016 Apr 11;13:19. doi: 10.1186/s12981-016-0103-1. eCollection 2016. Review
We employed an RNA-guided CRISPR/Cas9 DNA editing system to precisely remove the entire HIV-1 genome spanning between 5′ and 3′ LTRs of integrated HIV-1 proviral DNA copies from latently infected human CD4+ T-cells.
Via Kenzibit
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Scooped by
Gilbert C FAURE
February 3, 2016 12:27 PM
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The impact of HIV-1 on ILCs remains unknown. Kløverpris and colleagues find that ILCs are rapidly depleted from the blood of HIV-1-infected individuals during acute infection.
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Scooped by
Gilbert C FAURE
January 28, 2016 4:18 AM
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Soluble cervicovaginal biomarkers of inflammation, immune activation and risk of HIV acquisition are needed to reliably assess the safety of new biomedical prevention strategies including vaccines and microbicides.
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Scooped by
Gilbert C FAURE
January 22, 2016 1:42 PM
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Author Summary Despite the efficacy of ART to suppress HIV replication in blood, HIV-infected individuals experience persistent immunologic dysfunction and inflammation that predict mortality and have been related to a chronically injured...
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Gilbert C FAURE
January 6, 2016 2:05 PM
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PLoS One. 2016 Jan 5;11(1):e0146663. doi: 10.1371/journal.pone.0146663.
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Scooped by
Gilbert C FAURE
October 8, 2015 5:15 AM
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HIV particles are effectively trapped by the cervicovaginal mucus from women who harbor a particular vaginal bacteria species, Lactobacillus crispatus.
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Scooped by
Gilbert C FAURE
September 6, 2015 12:40 PM
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Interactions between hormonal contraceptives and various genital tract infections may alter cervical immunity and increase the risk for HIV seroconversion among women, according to recently published data.“Before this study, there were all these controversial...
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Rescooped by
Gilbert C FAURE
from Immune-Monitoring
August 26, 2015 5:08 AM
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HIV infection induces immune alterations, mainly in gut mucosa, where the main target cells reside. However, the evolution of the infection is variable among infected individuals, as evidenced by HIV controllers who exhibit low or undetectable viral load in the absence of treatment. The aim of this study was to evaluate the frequency, phenotype and activity of T and NK cells in peripheral blood and gut mucosa in a cohort of Colombian HIV controllers. Blood and gut biopsies were included. The fr
Via Marcelo de Carvalho Bittencourt
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Scooped by
Gilbert C FAURE
July 16, 2015 2:51 PM
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Vaccine. 2015 Jul 1. pii: S0264-410X(15)00875-0. doi: 10.1016/j.vaccine.2015.06.074. [Epub ahead of print]
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Scooped by
Gilbert C FAURE
June 27, 2015 1:03 PM
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