Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Scooped by Gilbert C FAURE
October 17, 2014 3:38 PM
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Decade in review—IBD: IBD—genes, bacteria and new therapeutic strategies - Nature.com

Decade in review—IBD: IBD—genes, bacteria and new therapeutic strategies Nature.com Patients homozygous for the ATG16L1 allele have marked structural alterations in their secretory apparatus along with transcriptional abnormalities in Paneth...
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Scooped by Gilbert C FAURE
November 15, 2013 5:34 AM
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Stomach bacteria switch off human immune defences to cause disease - Toronto NewsFIX

Stomach bacteria switch off human immune defences to cause disease - Toronto NewsFIX | Mucosal Immunity | Scoop.it
Stomach bacteria switch off human immune defences to cause disease Toronto NewsFIX New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the...
Gilbert C FAURE's insight:

where is defensin decreased? Paneth cells??

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Scooped by Gilbert C FAURE
February 27, 2013 11:16 PM
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Intestinal label-retaining cells are secretory precursors expressing Lgr5

Intestinal label-retaining cells are secretory precursors expressing Lgr5 | Mucosal Immunity | Scoop.it
From BioPortfolio: A new method to trace the lineage of slow cycling label-retaining cells (LRCs) in vivo identifies a population of LRCs that have features of committed Paneth ce...
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Scooped by Gilbert C FAURE
June 22, 2012 12:27 PM
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Immune system molecule weaves cobweb-like nanonets to snag ... - Nanowerk LLC

Immune system molecule weaves cobweb-like nanonets to snag ... - Nanowerk LLC | Mucosal Immunity | Scoop.it
Nanowerk LLCImmune system molecule weaves cobweb-like nanonets to snag ...Nanowerk LLCTwo of these, HD5 and HD6, are secreted by Paneth cells, specialized secretory cells located within the folds of the small intestinal lining.
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Scooped by Gilbert C FAURE
December 18, 2013 1:57 PM
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PLOS ONE: Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge

PLOS ONE: Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge | Mucosal Immunity | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
October 5, 2013 9:16 AM
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Intestinal cells may prompt Crohn's disease - Medical News Today

Intestinal cells may prompt Crohn's disease - Medical News Today | Mucosal Immunity | Scoop.it
Intestinal cells may prompt Crohn's disease
Medical News Today
A new study reveals that Crohn's disease may be a disorder of specialized intestinal cells, called Paneth cells. Researchers say this finding could provide new targets for treatment.
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Scooped by Gilbert C FAURE
November 5, 2012 1:37 PM
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Why Eating Less Makes Your Guts Healthier | Nutri-Link Ltd ...

Why Eating Less Makes Your Guts Healthier | Nutri-Link Ltd ... | Mucosal Immunity | Scoop.it
Paneth cells and innate mucosal immunity. Curr Opin Gastroenterol 2010;26:547-553 View Abstract. [6] Yilmaz OH, Katajisto P, Lamming DW, et al. mTORC1 in the Paneth cell niche couples intestinal stem-cell function to ...
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