I2BC Paris-Saclay

BSI 2021 is presenting special sessions:  

"Science & Société : La parole scientifique dans l'espace public": Many questions have raised by the period we have just passed through concerning the place of scientific speech in public debate, the role of experts (or so-called), interactions between researchers/experts, the media, politicians and the public. This roundtable will seek to shed light on what could/should be the contribution of researchers to public debates and the conditions for this contribution to be effective.

"Session étudiants": UPSaclay students are invited to attend the morning sessions and meet up with researchers. Free but registration required HERE.

"Satellite event - Alpha Fold": With the advent of AlphaFold, the BSI welcomes you to a round table meeting to discuss the impact and opportunity offered by this revolutionary tool. Free but registration required HERE.

Further information and details on how to access the conference location can be found on the BSI 2021 website.

Last call for registration at the Environmental and Agronomical Genomics 2021 Symposium until 13th October.

The Environmental and Agronomical Genomics 2021 symposium will be the opportunity to have an update on most recent environmental genomics research, as well as an overview of high scientific impact projects carried out in collaboration with France Genomique platforms. This year we are also celebrating the 10th anniversary of the GDR Génomique environnementale.

Contact person: Denis Faure

Interested in confocal microscopy ?
Come to the Imagerie-Gif Confocal Workshop to acquire and reinforce the theoretical basis of photonic microscopy and master the practical use of a full field and confocal microscope !
As well you will be able to integrate the principles and possibilities of new applications and developments in photonic microscopy and understand the complementarities of techniques from conventional microscopy to super-resolution !

Lecture (40% of the time)
- Reminder of conventional microscopy, videomicroscopy
- Introduction to confocal microscopy (instrument physics, acquisition, digitization, sampling, multiple labeling)
- Fast confocal microscope with Nipkow disk (Spinning-Disk)
- Understanding and using fluorochromes in confocal microscopy, proteins and fluorescent probes
- Preparation of live and fixed biological samples
- Processing and use of 2D and 3D images applied to microscopy
- Specific applications in confocal microscopy, FLIM, FRET, etc.
- Increased resolution and super-resolution (PALM, STORM, STED, SIM)
- Application seminars
Practical work (60% of the time)
A cycle of ten practical works over twenty hours will allow to reinforce the link between theory and applications, to recognize the elements implemented, to acquire images, to process them and to analyze them with ImageJ in particular.
One day will also be dedicated to the discovery of advanced techniques such as biphotonic excitation, light sheet microscopy, F-techniques (FRAP, photoactivation) and deconvolution.

More details here

Contact : Mébarek TEMAGOULT

For more than a year, the unprecedented context in which we live has prevented any meetings, a brand new format of physical event where Zeiss come to meet you, as close as possible to your place of work !

Tradeshows and conferences are ideal opportunities to discover new products and witness innovations firsthand. A real-time experience in an individual hands-on session will be offer to you to test new functionalities and give you the opportunity to talk to an expert about your needs. With Zeiss on your campus Truck,you can have the opportunity to experience microscopy workflows at first hand. Near your place of practice and taking into account the applicable hygiene measures, you can individually test the ZEISS instruments and solutions.

More details here

Contact : Sandrine.LECART@i2bc.paris-saclay.fr

In love with Integrative Structural Biology? The next @bsi2021 meeting is the PLACE-TO-BE from nov 29-dec 3 2021. Co-organized by @AFC_cristal and SFBiophys societies in Paris-Saclay campus. Please save the date, follow bsi2021, check http://bsi-2021.cnrs.fr, and RT!

The second French congress on Integrative Structural Biology (BSI), jointly organized by the Association Française de Cristallographie (AFC) and the Société Française de Biophysique (SFB), will take place on the Paris-Saclay campus from November 29 to December 3, 2021. The scientific program is available on the congress website. The congress can also be followed on twitter (@bsi2021). Structural biologists and biophysicists from I2BC (@I2BCParisSaclay), together with ENS-Paris-Saclay, Soleil, Ecole Polytechnic and ICSN are local organizers of the BSI202.

https://bsi-2021.cnrs.fr/

Contact: julie.menetrey@i2bc.paris-saclay.fr

The GO Paris-Saclay 2021 team won a gold medal and the "Best Inclusivity" prize at the iGEM 2021 international synthetic biology competition on Sunday, November 14.

The team's project "EndoSeek" aims to develop a new diagnostic tool for endometriosis, which is a painful and poorly understood pathology caused by the proliferation of uterine cells outside the uterus. Worldwide, this disease affects about 10% of women and can take up to 7 years to diagnose. Based on preliminary studies using small patient cohorts, certain blood microRNAs (miRNAs) may be biomarkers of the disease.
The team has developed a machine learning program that will allow identification of new endometriosis biomarkers with future cohorts. In experiments conducted this summer at I2BC, students exploited Cas13a and Cas14a1 nucleases for miRNA detection. They created a video game to educate adults and children over the age of 10 about endometriosis and synthetic biology. Finally, following their dialogue with patients and physicians, they questioned the ethical implications of diagnostics.
The team was awarded the Best Inclusivity Award for outstanding efforts to include people with diverse identities. The students thought about the position of LGBT+ people in their project and created a multi-language, voice-assisted website with color customization.
This project was supported by the I2BC, the Faculty of Sciences of the University of Paris-Saclay, La Diagonale Paris-Saclay, EUGLOH (European University Alliance for Global Health), the Graduate School Life Sciences and Health, IDT and Promega.

Team 2021 supervisors included Téo Hébra (ICSN) and 5 members of the I2BC: Philippe Bouloc, Stéphanie Bury-Moné, Emma Piattelli, Ombeline Rossier and Charlène Valadon.
For more information, see the wiki https://2021.igem.org/Team:GO_Paris-Saclay and the video https://video.igem.org/w/ihqYR3UfveimEtZVv7x6jE.

The IMAPP group is prominently involved in the MéDynA second plenary meeting, 6-9 September, 2021 at Ile d'Oléron (organising committee: Sonia Fieulaine, Stéphane Bressanelli, Maïté Paternostre, Edith Godard, Yves Boulard).

MéDynA is a 'GdR' (coordination of labs all across France around a specific research topic) whose objectives are to: * Bring together French labs studying by diverse means the dynamical pathways leading to self-organised protein assemblies or protein-based assemblies (incl. peptidomimetics)
* Forge a common language so as to benefit from the multiple expertise stemming from B13https://medyna.cnrs.fr/les-actualites/deuxieme-pleniere/B14 biophysics, chemistry, physics and mathematics to understand and master mechanisms of protein assembly
* Foster emergence of interdisciplinary and novel research projects
* Set up a nationwide interdisciplinary network useful to all researchers, whether at an early career stage (such as graduate students and postdocs) or well established

More information here

Contact: gdr.medyna@ibpc.fr