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I2BC Paris-Saclay
November 24, 2022 9:39 AM
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November 25th "Host-Microbe Interactions" and "Molecular Tools for Biology"
The “Drug and Technology for Health” Department is part of the CEA’s Joliot Institute, as is the I2BC. The aim of the DMTS-I2BC day is to get to know each other and to encourage potential collaborations. Two themes were chosen for this first edition: “Host-Microbe Interactions” and “Molecular Tools for Biology”. More information and program: here
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I2BC Paris-Saclay
November 24, 2022 9:24 AM
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Holy coli: a mouse in the odour of sanctity
An art project to pay tribute to the laboratory mouse, often sacrificed on the altar of science. More information: here Contact: Sylvie Lautru <sylvie.lautru@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
October 24, 2022 4:45 AM
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BSI@Paris-Saclay - nov 29, 2022
The Structural Integrative Biology (BSI) community is organising its first Scientific Day on Tuesday 29 November 2022 from 9:00 am to 5:00 pm at the I2BC (Auditorium of Bât21, CNRS campus, Gif-sur-Yvette) with the participation of the national infrastructures Soleil, Infranalytics and FRISBI and the European infrastructure Instruct-Eric. The objective of this day is to bring together the local BSI community of Paris-Saclay in order to foster new interactions. Speakers: Harald SCHWALBE (Director of INSTRICT-ERIC) Carine VAN HEIJENOORT (Director of Infranalytics) Andy THOMPSON (Resp. scientist Synchrotron Soleil) Stéphane BRESSANELLI (Resp. PF CryoEM, I2BC, FRISBI) And 5 oral presentations selected on abstract – Free but mandatory registration on the conference website – Submission of abstracts (Posters and Oral Presentations) on the congress website. The deadline for submission of abstracts for oral presentations is 21 October 2022. The selection will be made by the organising committee. We are looking forward to seeing many of you. Contacts: julie.menetrey@i2bc.paris-saclay.fr and ewen.lescop@cnrs.fr Sponsors : I2BC, ICSN, FRISBI, Infranalytics, Soleil, LM@W
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I2BC Paris-Saclay
September 21, 2022 12:14 PM
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Third MéDynA plenary meeting (Assembly mechanisms and dynamics of self-organised protein-based complexes)
MéDynA third plenary meeting, 17-21 October, 2022 at Ile d'Oléron. More information here Contact: Stéphane Bressanelli <stephane.bressanelli@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
June 15, 2022 11:27 AM
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After two years, the whole Genome Biology Department meet in person to celebrate the VI Genome Biology Day
After two years, the whole Genome Biology Department meet in person to celebrate the VI Genome Biology Day. Last May 20th the Genome Biology Department met during a whole day to present and discuss the research projects carried out by the researchers of the department. Great short talks and posters covering studies on bioinformatics and genomics; gene expression and regulation; and dynamics and stability of genomes were presented during the day. In addition, two keynote talks were presented by Cynthia Sharma (University of Würzburg, Germany) and Ian Henderson (University of Cambridge, UK). Cynthia’s talk covered novel aspects of gene regulation by non-coding RNAs in Helicobacter pylori and Campilobacter jejeuni. Ian’s presentation focused into how the the Arabidopsis pan-centromere revealed the contribution of transposable elements on centromere evolution. At the end of the day, the winners of the ‘Best Talk Awards’ (James Provan, Barre’s lab & Kevin André, Souturina’s lab) and of the ‘Best Poster Awards’ (Amelie Besombes, Barre’s Lab; Kam Pou Ha, Bouloc’s lab and Estelle Leroy, Rougmaille’s lab) were announced. Altogether, this was a great day in which the GB department could meet and discuss about their favorite research topic: The Biology of Genomes. Contact: organizing commeette <virginia.lioy@i2bc.paris-saclay.fr>,<yoshiharu.yamaichi@i2bc.paris-saclay.fr> & <angelique.deleris@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
June 3, 2022 10:16 AM
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French Days of Photosynthesis: June 9th-10th - Klaus Brettel's Portait
Klaus Brettel studied physics and biophysics at the universities of Stuttgart and Gießen (Germany) and obtained his PhD in 1985 for spectroscopic work on primary reactions in photosynthesis with Prof. H. T. Witt at the Max-Volmer-Institute of the Technische Universität Berlin (TUB). After a postdoctoral stay in the bioenergetics lab at CEA Saclay (France), he habilitated in physical chemistry at the TUB in 1990. He accepted a permanent researcher position at CEA Saclay in 1991. Twenty years ago, he shifted his center of interest from photosynthesis to DNA photolyases and cryptochrome blue light receptors. More recently, he also contributed to the elucidation of the reaction mechanism of another light-driven enzyme, fatty acid photodecarboxylase (FAP).
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I2BC Paris-Saclay
April 15, 2022 9:31 AM
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6th edition of the Paris-Saclay Physics & Biological Systems conference PhysBio2022 - June 27-29 2022 - ENS Paris-Saclay.
Early-bird registrations are now open until the 15th of May at a discount rate, and free for students. The PhysBio conference series brings together international scientists working at the interface between Physics and Biology. The scope of the conference is intentionally broad, comprising cell and tissue mechanics, biomedical engineering, morphogenesis and self-assembling, but also instrumental and methodological developments. This breadth of topics goes together with a focus on excellent speakers, to whom we provide long-format talks that allow them to make their latest research accessible to all attendants, non-specialists and students included. As discoveries of the coming decades will come from young generations, PhysBio conference series is endowed with a student committee that selected a dozen of short talks from outstanding PhD students. Finally, we encourage all attendees to submit a poster contribution to initiate the discussion on their research topics with all the other participants. Registration until May 15th: http://lptms.u-psud.fr/physbio2022/registration/ The organizing committee, Christophe Le Clainche, Martin Lenz, Karen Perronet, Marie-Claire Schanne-Klein, and François Treussart.
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I2BC Paris-Saclay
April 15, 2022 7:56 AM
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Ecole thématique Ecoclim2022 - Orsay - 7 au 10 juin 2022
L'école thématique Ecoclim2022 aura lieu à Orsay du 7 au 10 juin 2022. Cette école a pour objectif d'offrir une formation de base sur les enjeux environnementaux aux chercheuses et chercheurs de toutes disciplines. Les renseignements et le formulaire d'inscription sont disponibles sur la page https://indico.ijclab.in2p3.fr/event/7951 Notez qu'un suivi en distanciel sera possible, de préférence pour les personnes en province, mais sans interaction possible. Les organisateurs : Guillaume Blanc et Guillaume Roux Au programme Cours introductif sur le climat Jean-Yves Grandpeix (LMD) Dérèglement climatique et impacts Amaëlle Landais (LSCE) Didier Paillard (LSCE) Jeanne Gherardi (LSCE) Mélanie Becker (LIENSs) Cycles biogéochimiques, sols et agriculture Bertrand Guenet (LG-ENS) Julia Le Noé (ENS) Petros Chatzimpiros (LIED) Trajectoires de décarbonation Henri Waisman (IDDRI) Gilles Billen (METIS) ( à confirmer) Aurélien Bigo () Emmanuelle Frenoux (LISN) Tamara Ben Ari (iEES, Labo1point5) Scénarios et modèles de sociétés Luc Semal (CESCO) Timothée Parrique (Lund University) Emmanuel Combet / Valérie Quiniou / David Marchal (Ademe)
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I2BC Paris-Saclay
March 30, 2022 5:55 AM
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Scientific day in memory of Agnès Delahodde
Throughout the day, there will be scientific presentations by colleagues and collaborators and personal tributes to Agnès Delahodde. Josette Banroques - IBPC, Paris & Bruno Sargueil - Faculty of Pharmacy, Paris DNA endonuclease and RNA maturase activities of two intron-encoded proteins from yeast mitochondria Teresa Rinaldi - Universita la Sapienza, Rome Mitochondrial function and lipids in S. cerevisiae Monique Bolotin - GQE-Le Moulon, Gif-sur-Yvette Vincent Procaccio - CHU, Angers Disease modeling and drug screening of mitochondrial complex I disorders: from Podospora anserina to Human Agnès Rötig - Institut Imagine, Paris & Véronique Paquis - CHU, Nice Yeast does not lose the north or the south in the field of mitochondrial diseases: in the North Agnès Rötig in the South Véronique Paquis Laras Pitayu - IJM, Paris (Mitochondrial) Genome Stability Testimony Renaud Legouis - I2BC, Gif-sur-Yvette Mitochondrial rebuilding after acute heat stress relies on autophagy Free but required registration before 22 April 2022 https://evento.renater.fr/survey/inscriptionjournee-d-hommage-agnes-delahodde-ideapch1 Capacity 200 people + Video broadcast more information: here Contact: day4agnes@i2bc.paris-saclay.fr
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I2BC Paris-Saclay
March 21, 2022 5:18 AM
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23rd National Congress on Transposable elements (CNET) July 4th-6th
We are pleased to announce the 23rd annual meeting organized by the French research community working on transposable elements (CNET). This event gathers researchers interested in transposable elements, including population and comparative genomics, molecular and cellular mechanisms, ecology and evolution. This year the meeting will take place July 4–6 in Gif-sur-Yvette, near Paris. We invite contributions including molecular, genetics and cellular studies, as well as bioinformatics and mathematical modeling approaches, applied to a wide range of model organisms (prokaryotes, plants, yeast, insects, ciliates, vertebrates, ...). The program will include invited talks, selected talks and ample time for poster presentation and discussions. Junior researchers are particularly encouraged to apply for oral presentations. More information: here
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I2BC Paris-Saclay
February 21, 2022 7:47 AM
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3-days Training in Flow Cytometry
Imagerie-Gif and CNRS Formation Entreprises are organizing a training to blow your mind with flow cytometry. We offer you to acquire the theoretical bases in flow cytometry (analysis and sorting, experimental strategies), to be informed of applications and developments in very varied fields of application, and to initiate or deepen the use of analyzers and sorters. The training will be split in theoretical mornings and practical afternoons. Practical afternoons will take place on GIF and ORSAY campus. The training is opened to Student, researcher and Engineer. https://cnrsformation.cnrs.fr/atelier-cytometrie?mc=Cytom%C3%A9trie Contact person: BOURGE Mickael
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I2BC Paris-Saclay
January 25, 2022 5:46 AM
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First ICNS/I2BC Morning-Meeting February 8th at 9.30 a.m
The ICSN and the I2BC are the two major units of the CNRS campus of Gif sur Yvette. The “institut de Chimie des substances naturelles” (ICSN), with a staff of nearly 150 people, is the chemistry pole of the CNRS campus in Gif sur Yvette. This unit develops activities at the chemistry-biology interface, with natural substances as the object of study and main source of inspiration. Equipped with numerous platforms, including two NMR platforms, the ICSN will host an NMR apparatus from an I2BC team when it moves from the CEA-Saclay to the Gif-sur-Yvette campus. However, the links between our two institute are not limited to NMR; the purpose of this first morning is to introduce you to ICSN in the hope of encouraging new collaborations. This first Morning-Meeting, which will be the first of a series, will be oriented towards the platforms of the two units and duos of researchers to illustrate the fruitful collaborations already in place. Please come in large numbers to meet your chemical colleagues. Due to health conditions, the meeting will be held in hybrid mode, both in the auditorium of Building 21 on the Gif-sur-Yvette campus and on Zoom. See program on the website: here Contact for link: communication@i2bc.paris-saclay.fr
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I2BC Paris-Saclay
December 20, 2021 3:57 AM
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I2BC comes forward at Declics event on 18 November 2021
Several I2BC members participated in the Declics outreach event at French high school Lycée Sainte-Marie (Antony) on 18 Nov 2021. Declics is a half-day outreach event organized by Cercle FSER, in which scientists (researchers, engineers, technicians, with a permanent or short-term position) visit a high school to talk about science, research jobs and the process of building up knowledge. On 18 November, a team of 7 scientists met 38 high school students and 2 high school teachers of Lycée Sainte-Marie (Antony). The team included 5 scientists from I2BC: Jessica Andreani (team captain, B3S department), Adriana Alberti (Genome Biology department), Audrey Esclatine (Virology department), Vicky Lioy (Genome Biology department) and Nathalie Scrima (Virology department). After an overall presentation by the team captain, almost two hours of speed-meetings in small groups. A very positive experience! More information here. Contact person: Jessica Andreani
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I2BC Paris-Saclay
November 24, 2022 9:28 AM
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MICROBIOLOGY DEPARTMENT DAY - TRIBUTE TO MICKAEL DUBOW: 30 SEPTEMBER 2022
The morning was devoted to personal and scientific testimonies which highlighted Mike's imagination, insatiable curiosity and innovative ideas as well as his great popularity with students in France and abroad. The afternoon was devoted to scientific presentations, around 3 themes that Mike was passionate about: biofilms, extremophilic bacteria and environmental phages. These presentations were given by researchers from the department and by two guest researchers, Adrienne Kish (MNHN, Paris) and Romain Briandet (Institut Micalis, Jouy-en-Josas).
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I2BC Paris-Saclay
November 24, 2022 8:59 AM
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The 6th users meeting of the The French Infrastructure for Integrated Structural Biology (FRISBI) will be held on December 9th 2022 in Gif-sur-Yvette. Preliminary program and registration: https://frisbi.eu/network/user-community/ More information: here Contact: Sophie Zinn <sophie.zinn@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
September 22, 2022 4:43 AM
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Looking for an intership ?
You are looking for an internship, come and meet us on October 15 at I2BC, 1 avenue de la terrasse in Gif sur Yvette. More information: here
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I2BC Paris-Saclay
June 15, 2022 11:54 AM
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Save the dates: MICROBES Symposium September 7-8, 2022
The OI MICROBES is pleased to invite you to the 1st MICROBES Symposium that will be held on September 7-8, 2022 in the Auditorium Blandin of the Laboratoire de Physique des Solides, Orsay, 1 rue Nicolas Appert, Bâtiment 510. The interdisciplinary MICROBES symposium is a yearly internal meeting where the teams of the Paris-Saclay MICROBES community present their research. The Symposium will have invited speaker presentations, posters and selected flash talks of posters. The symposium PROGRAM has five Plenary and Poster Sessions: Session 1 - Health and Disease (wed 7/9/22 morning) Session 2 - Ecology and Evolution (wed 7/9/22 afternoon) Session 3 - Fundamental Microbiology (wed 7/9/22 afternoon & thu 8/9/22 morning) Session 4 - Systems Biology and Engineering (thu 8/9/22 morning & afternoon) Session 5 - Agriculture and Food (thu 8/9/22 morning) Confirmed Speakers of the symposium are (to be completed): Mathieu Almeida (MGP) Harold Auradou (FAST) Théodore Bouchez (PROSE) Amandine Cornille (GQE) Bernard Delmas (VIM) Marina Elez (MICALIS) Denis Faure (I2BC) Tatiana Giraud (ESE) Amélie Leforestier (LPS) Bruno Le Pioufle (Institut d'Alembert) Virginia Lioy (I2BC) Filipa Lopes (LGPM) Florent Malloggi (NIMBE) Françoise Rul (MICALIS) Guillaume Tresset (LPS) David Vallenet (GM) INSCRIPTIONS are free but mandatory. Note that places are limited. Inscription deadline: August 31, 2022. Flash talk submission deadline: July 15, 2022. REGISTER HERE For more information: oi.microbes@universite-paris-saclay.fr
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I2BC Paris-Saclay
June 15, 2022 11:09 AM
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Scientific day of Memory in Mike Dubow September 30th
The morning will be devoted to tributes and testimonials from people who have been fortunate enough to work with Mike Dubow during his teaching and research activities. The afternoon will be devoted to a symposium of the Department of Microbiology, which will focus on three scientific themes dear to Mike: extremophiles, biofilms and environmental phages. Each theme will include a presentation by a member of the Department and an external collaborator. Registration: https://evento.renater.fr/survey/hommage-a-michael-dubow-vendredi-30-septembre-2022-iary7xq2 Contact: hommage.mike@i2bc.paris-saclay.fr
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I2BC Paris-Saclay
June 3, 2022 10:12 AM
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French Days of Photosynthesis: June 9th-10th - Diana Kirilovsky's Portait
Diana Kirilovsky was born in Buenos Aires. She obtained her Ph.D. in Biochemistry at the Hebrew University of Jerusalem (Israel). After post-doctoral training in France at CNRS and CEA laboratories, she obtained a Senior Research Scientist position at the CNRS in 1991. She worked at several CNRS laboratories in Gif sur Yvette, l’ENS and the CEA Saclay. She finished her scientific career as Research Director “Classe Exceptionnelle (DRCE1, CNRS) and as Group Leader in the Institute of Integral Biology of the Cell (I2BC, CNRS). Diana Kirilovsky has studied the molecular biology and physiology of cyanobacteria for over 35 years focusing on light induced processes, in particular, the role of light as a source of stress and as a regulator. She principally studied the mechanisms of photoinhibition, photoprotection and light acclimation in cyanobacteria. A major contribution of her group was the discovery and characterization of a new mechanism of photoprotection in cyanobacteria involving a unique type of photoactive carotenoid protein. She has more than 100 peer-rewieved publications (including Science, PNAS, Plant Cell and JACS). She gave more than 50 invited conferences in international meetings and workshops including 7 Gordon Conferences (photosynthesis, carotenoids and photoreceptors). She was a member of the steering committees of the French and International Photosynthesis Societies during several years and of the French Photobiology Society .
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I2BC Paris-Saclay
April 15, 2022 8:30 AM
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Metabiodivex summer school
METABIODIVEX, in which the I2BC is participating, and the IRN i-NPChem are organising the first thematic school entitled "Molecular Exploration of Biodiversity: New Challenges, New Strategies". It will take place from June 26 to July 1st 2022 in Aussois. The themes will be : - Chemodiversity in the era of "Big Data" - Drug Discovery: Challenges and Strategies - Evolution and diversity of plant metabolism - Chemical ecology of marine organisms - Discovery and production of microbial metabolites: from the gene to the molecule - Digital chemistry and quantum computing Registrations until May 15th 2022: https://www.azur-colloque.fr/DR04/inscription More information: https://metabiodivex.sciencesconf.org/ Contact: Sylvie LAUTRU <sylvie.lautru@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
April 5, 2022 10:41 AM
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Alex von Appen seminar on April the 14th at 11.am: "Nuclear self-assembly following vertebrate mitosis” in I2BC Gif-sur-Yvette
"Nuclear self-assembly following vertebrate mitosis” is Alex von Appen seminar on April the 14th at 11 am in the auditorium of building 21 at I2BC in CNRS Gif-sur-Yvette. Abstract: During cell division, remodelling of the nuclear envelope enables chromosome segregation by the mitotic spindle1. The reformation of sealed nuclei requires ESCRTs (endosomal sorting complexes required for transport) and LEM2, a transmembrane ESCRT adaptor2-4. Here we show how the ability of LEM2 to condense on microtubules governs the activation of ESCRTs and coordinated spindle disassembly. The LEM motif of LEM2 binds BAF, conferring on LEM2 an affinity for chromatin5,6, while an adjacent low-complexity domain (LCD) promotes LEM2 phase separation. A proline-arginine-rich sequence within the LCD binds to microtubules and targets condensation of LEM2 to spindle microtubules that traverse the nascent nuclear envelope. Furthermore, the winged-helix domain of LEM2 activates the ESCRT-II/ESCRT-III hybrid protein CHMP7 to form co-oligomeric rings. Disruption of these events in human cells prevented the recruitment of downstream ESCRTs, compromised spindle disassembly, and led to defects in nuclear integrity and DNA damage. We propose that during nuclear reassembly LEM2 condenses into a liquid-like phase and coassembles with CHMP7 to form a macromolecular O-ring seal at the confluence between membranes, chromatin and the spindle. The properties of LEM2 described here, and the homologous architectures of related inner nuclear membrane proteins7,8, suggest that phase separation may contribute to other critical envelope functions, including interphase repair8-13 and chromatin organization14-17. In reference to: LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. von Appen A, LaJoie D, Johnson IE, Trnka MJ, Pick SM, Burlingame AL, Ullman KS, Frost A.Nature. 2020 Jun;582(7810):115-118. doi: 10.1038/s41586-020-2232-x. Epub 2020 Apr 29.PMID: 32494070 Contact: Sophie Zinn-Justin <sophie.zinn@i2bc.paris-saclay.fr>
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I2BC Paris-Saclay
March 29, 2022 4:21 AM
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Save the date! - I2BC PhD students' symposium - 16-17th June
Today, we announce an exciting event organized on the CNRS campus of Gif-sur-Yvette, by the young scientists of I2BC and for I2BC doctoral students: the I2BC doctoral students' symposium. Save the date : 16 & 17th June. Essentially build around the scientific work of I2BC doctoral students, speakers will also be invited to these two days of seminars and posters. Participating in doctoral students' symposium gives you the opportunity to have an overview of the new projects of I2BC groups.
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I2BC Paris-Saclay
March 21, 2022 5:08 AM
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French Days of Photosynthesis: June 9th-10th
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I2BC Paris-Saclay
February 21, 2022 7:38 AM
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EMBO in-person workshop on Protein Termini in Bergen Norway 8-11 June 2022
EMBO in-person workshop on Protein Termini in Bergen Norway 8-11 June 2022 Here is the complete list of 32 confirmed speakers: 15-20 additional speakers will be selected from the abstracts. Don't miss this chance to join world-leading PI in the beautiful city of Bergen. Deadline 11 March 2022!
https://meetings.embo.org/event/21-protein-termini
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I2BC Paris-Saclay
January 13, 2022 5:14 AM
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BSI 2021: one week with intensive scientific discussions!
The 2nd french congress on integrative structural biology took place on november29th-December 3rd at the Centrale Supelec building, located on the Paris- Saclay plateau. Co-organized by the Association Française de Cristallographie and the Société Française de Biophysique, it brought together over 250 participants of which 63 students. The program of the event included 13 sessions covering health issues, DNA/RNA world, membrane proteins, intrinsically disordered proteins, macromolecular assemblies. Several round tables allowed discussions about “formation tout au long de la vie”, ” interactions entre académie/industrie”, ” infrastructures” and “la parole scientifique dans l’espace public”. A satellite event on the revolutionnary tool AlphaFold ended up the congress. Many thanks to the institutional partners (CNRS, CEA, I2BC, ICSN, Ecole Polytechnique, ENS Paris-Saclay, FRISBI, IRRMN, Université Paris-Saclay , Université Paris-Saclay Graduate School Life Sciences and Health, Synchrotron SOLEIL, France-Bioimaging) and industrial partners (Bruker, Cytiva, CytobodX, Dynamic Biosensors, Eurisotop, GenScript, Horiba, Innova-Chem, Jeol, NMR-Bio, Refeyn, Sanofi, Servier, Sptlabtech , Thermofisher, et Twist ) for their support. Congratulations to Magda Teixeira Nunes and and Luce Dreno who won the best poster prize of the AFC and SFB, respectively! BSI website Contact person: Julie Ménétrey
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