Geriatría HGG Journal Club
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April 10, 2024 3:06 AM
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Exploring Predictive Factors for Potentially Avoidable Emergency Department Transfers: Findings From the FINE Study

Exploring Predictive Factors for Potentially Avoidable Emergency Department Transfers: Findings From the FINE Study | Geriatría HGG Journal Club | Scoop.it

To assess the prevalence of potentially avoidable transfers (PAT) and identify factors associated with these transfers to emergency departments (EDs) among nursing home (NH) residents.

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April 10, 2024 2:44 AM
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Talking With Patients About the New Anti-amyloid Alzheimer Disease Medications

The number of persons in the United States with Alzheimer disease will approach 14 million by 2060. New anti–amyloid-β infusions have been shown to reduce the volume of amyloid plaques on positro
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April 4, 2024 7:59 AM
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Alzheimer’s Disease — Managing Stages of Dementia | New England Journal of Medicine

This Double Take video reviews the stages of Alzheimer’s disease as well as pharmacologic and nonpharmacologic management for each stage.
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March 6, 2024 4:47 AM
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Weaker Link Than Expected Between Exercise and Less Cognitive Decline | Dementia and Cognitive Impairment | JAMA | JAMA Network

Weaker Link Than Expected Between Exercise and Less Cognitive Decline | Dementia and Cognitive Impairment | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it
Previous research has tied increased physical activity with a lower risk of cognitive decline and dementia. But a recent meta-analysis involving 104 studies that included more than 341 000 participants suggested the association might be smaller than expected. The researchers did note in JAM
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February 27, 2024 3:37 AM
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Alzheimer’s Disease Biomarkers — Timing Is Everything | NEJM

Alzheimer’s disease typically evolves over a period of several years before an affected person seeks medical attention for a diagnosis. The pathologic features of the brain in patients wit
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February 17, 2024 4:46 AM
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New horizons in the diagnosis and management of Alzheimer’s Disease in older adults | Age and Ageing | Oxford Academic

New horizons in the diagnosis and management of Alzheimer’s Disease in older adults | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

A timely, accurate diagnosis of ad with access to appropriate multidisciplinary support and treatment improves quality of life and reduces carer strain. Biomarkers have the potential to help support this process but should be used as part of a clinical-biological diagnosis by specialists with experience in interpreting the results. Co-pathology is frequent in older adults, and the recent advances in ad biomarker-assisted diagnosis should not be to the detriment of the diagnosis and treatment of other causes of cognitive impairment. The development of new immunological therapies for ad is exciting for patients and professionals alike but the results of current trials should be considered cautiously and their findings’ applicability to more typical patient groups need to be weighed carefully. We believe that a patient-centred- approach using the tenets of CGA remains a robust framework into which new diagnostic tools and treatments can be adopted.

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February 17, 2024 4:36 AM
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Ecografía a pie de cama. Indicaciones y utilidad en medicina interna - ClinicalKey

Ecografía a pie de cama. Indicaciones y utilidad en medicina interna - ClinicalKey | Geriatría HGG Journal Club | Scoop.it

La ecografía a pie de cama es ya una herramienta de gran utilidad para el médico internista, que complementa su exploración física de forma rápida y relativamente sencilla. Así, contribuye amejorar el proceso diagnóstico, ayuda en la toma de decisionesclínicas en tiempo real y facilita la realización de procedimientosinvasivos. Además, al tratarse de una exploración más focalizada que las ecografías regladas, requiere de un entrenamiento menos prolongado.Actualmente, muchos servicios de medicina interna ya cuentan con equipos destinados a la realización de ecografías a pie de cama, y es de esperar que esta técnica se integre cada vez más en la práctica clínica habitual, ante la mayor disponibilidad de dispositivos portátiles y el creciente interés que suscita entre los internistas 

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February 17, 2024 4:34 AM
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Alteraciones neuropsicológicas en pacientes en tratamiento con diálisis peritoneal - ClinicalKey

Alteraciones neuropsicológicas en pacientes en tratamiento con diálisis peritoneal - ClinicalKey | Geriatría HGG Journal Club | Scoop.it

El funcionamiento ejecutivo global fue mejor en los pacientes en DP que en aquellos en HD. Los resultados muestran el efecto positivo de la DP sobre las funciones ejecutivas, lo que debe tenerse en cuenta a la hora de la elección de la TRS. Las asociaciones observadas entre los factores bioquímicos y el rendimiento muestran la importancia de mantener un adecuado estado nutricional en estos pacientes.

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February 17, 2024 4:20 AM
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Treatment-Resistant Depression in Older Adults | NEJM

Treatment-Resistant Depression in Older Adults | NEJM | Geriatría HGG Journal Club | Scoop.it

The appropriate dose of antidepressant medicine

for older adults with depression is similar to that

for younger adults, and older persons can receive

what might be perceived as a high dose without

negative side effects (Table 1).20 However, older

patients are more prone to adverse effects associated

with antidepressants, especially falls (Table

2).21 Given high reported rates of medication

nonadherence in depression, establishment and

maintenance of a therapeutic alliance to support

adherence surveillance can improve outcomes in

patients with depression

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February 2, 2024 12:55 PM
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Care pathways in older patients seen in a multidisciplinary same day emergency care (SDEC) unit | Age and Ageing | Oxford Academic

Care pathways in older patients seen in a multidisciplinary same day emergency care (SDEC) unit | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Same day emergency care (SDEC) services are being advocated in the UK for frail, older patients in whom hospitalisation may be associated with harm but there are few data on the ‘ambulatory pathway’. We therefore determined the patient pathways pre- and post-first assessment in a SDEC unit focussed on older people.

 

SDEC assessment in older, frail patients was associated with a 2-fold increase in frequency of healthcare interactions with complex care pathways involving multiple services. Our findings have implications for the development of admission-avoidance models including cost-effectiveness and optimal delivery of the multi-dimensional aspects of acute geriatric care in the ambulatory setting.

 

Servicio de Geriatría's insight:

Rich clinical data are laborious to collect but are critical to understand and adequately resource SDEC services and inform policy; outcomes cannot be directly extrapolated from services for younger patients or pre-selected groups. Our findings will therefore inform development of SDEC focussed on the older acute medi-cal take population and other admission-avoidance models for older patients.

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February 2, 2024 12:51 PM
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Sodium-glucose cotransporter-2 inhibitors (SGLT2) in frail or older people with type 2 diabetes and heart failure: a systematic review and meta-analysis | Age and Ageing | Oxford Academic

Sodium-glucose cotransporter-2 inhibitors (SGLT2) in frail or older people with type 2 diabetes and heart failure: a systematic review and meta-analysis | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

In older or frail patients with T2D and HF, SGLT2Is are consistently linked with a decrease in total mortality and the overall burden of cardiovascular (CV) events, including HHF events and cardiac death, but not protective for macrovascular death or renal events. Adverse events were more difficult to quantify but the risk of diabetic ketoacidosis or acute kidney injury was not significantly increase.

 

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February 2, 2024 12:50 PM
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Constructing a quality frailty index | Age and Ageing | Oxford Academic

Constructing a quality frailty index | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

The number of papers on frailty has risen exponentially over the last decade, with an ever-increasing diversity of researchers investigating the role of frailty..

 

The recognition of frailty as a research priority across a range of conditions is likely to result in a renewed focus on measuring frailty explicitly and prospectively in clinical studies [14]. As with all research, quality of study design and data collection is critical, and the principles and structured approach to formulating a frailty index outlined in this article are likely to prove invaluable to researchers, particularly those evaluating frailty for the first time.

 

Servicio de Geriatría's insight:

You  get out what you put in

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February 2, 2024 12:33 PM
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Cognitive dysfunction after covid-19 | The BMJ

Cognitive dysfunction after covid-19 | The BMJ | Geriatría HGG Journal Club | Scoop.it

What you need to know

• Cognitive problems are common after acute

SARS-CoV-2 infection and can be disabling and

frightening

• Symptoms tend to improve, but this may take up to

a year. Those with chronically persistent symptoms

lasting more than 12 months have a lower chance of

improving

• Symptoms usually fluctuate

• Assessment should be directed to documenting the

nature and trajectory of the impairment and excluding

alternative diagnoses

• Self-management techniques may help patients

manage their condition

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April 10, 2024 2:58 AM
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¿Cómo detectar a los pacientes mayores no institucionalizados en riesgo de malnutrición durante su hospitalización? Comparación de 8 herramientas de cribado de malnutrición o de riesgo nutricional ...

¿Cómo detectar a los pacientes mayores no institucionalizados en riesgo de malnutrición durante su hospitalización? Comparación de 8 herramientas de cribado de malnutrición o de riesgo nutricional ... | Geriatría HGG Journal Club | Scoop.it
AntecedentesLa prevalencia de malnutrición es elevada entre la población mayor. El
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April 4, 2024 8:16 AM
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Heart failure with preserved ejection fraction: everything the clinician needs to know

Heart failure with preserved ejection fraction: everything the clinician needs to know | Geriatría HGG Journal Club | Scoop.it

Heart failure with preserved ejection fraction (HFpEF) is increasingly recognised and diagnosed in clinical practice, a trend driven by an ageing population and a rise in contributing comorbidities, such as obesity and diabetes. Representing at least
half of all heart failure cases, HFpEF is recognised as a complex clinical syndrome.
Its diagnosis and management are challenging due to its diverse pathophysiology, varied epidemiological patterns, and evolving diagnostic and treatment approaches. This Seminar synthesises the latest insights on HFpEF, integrating findings from recent clinical trials, epidemiological research, and the latest guideline recommendations.

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March 7, 2024 8:24 AM
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Making care closer to home a reality (The King's Fund)

Making care closer to home a reality (The King's Fund) | Geriatría HGG Journal Club | Scoop.it

El fracaso en desarrollar e invertir en atención primaria y comunitaria se sitúa en uno de los fracasos más grandes y duraderos de la política social y sanitaria británica desde hace más de 30 años

Servicio de Geriatría's insight:

Los "specific enablers" para mejorar la situación se sitúan en 3 ejes: Plantillas, Planificar-Contratar-Ejecutar y Capital. Focalizando en liderazgo (primaria vs hospitalaria, mas alineación visión-programa, mayor visión a largo plazo), cambio cultural (resultados centrados en personas, contención de riesgos, toma de decisiones de organismos nacionales, mejorar el status de AP, mayor contacto con staff y organizaciones del sector, mayor contacto conn la población ) y en la implementación (integración operativa > integración organizativa y más foco a nivel local y menos en el sistema y el nivel nacional)...como dicen los autores del report "this may seem like an impossible task...but nothing is impossible"

 

 

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February 29, 2024 5:01 AM
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Cognition and Memory after Covid-19 in a Large Community Sample | NEJM

Abstract Background Cognitive symptoms after coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are well-recognized. Whethe
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February 27, 2024 3:35 AM
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Biomarker Changes during 20 Years Preceding Alzheimer’s Disease | NEJM

Abstract Background Biomarker changes that occur in the period between normal cognition and the diagnosis of sporadic Alzheimer’s disease have not been extensively investigated in longitudina
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February 17, 2024 4:45 AM
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Summary of best evidence for prevention and management of frailty | Age and Ageing | Oxford Academic

Summary of best evidence for prevention and management of frailty | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

A total of 44 publications were finally included, including 12 guidelines, 5 best practices, 4 expert consensus, 5 evidence summaries and 18 systematic reviews. Through the induction and integration of the evidence, the evidence was finally summarised from eight aspects: frailty screening, frailty assessment, exercise intervention, nutrition intervention, multi-domain intervention, drug administration, social support and health education, and 43 best evidences were formed.

 

This study summarised the best evidence for the prevention and management of frailty from eight aspects, which can provide guidance for clinical or community medical staff to develop and apply frailty intervention and practice programmes for older people and improved the clinical outcome and quality of life of older people.

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February 17, 2024 4:35 AM
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Prognosis of acute heart failure in patients followed up in nursing homes in Spain: Results from the RICA registry - ClinicalKey

Prognosis of acute heart failure in patients followed up in nursing homes in Spain: Results from the RICA registry - ClinicalKey | Geriatría HGG Journal Club | Scoop.it

Nursing home residents with heart failure showed higher one-year mortality which couldbe due to worse functional status, higher comorbidity, and cognitive deterioration.

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February 17, 2024 4:29 AM
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Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials | The BMJ

Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials | The BMJ | Geriatría HGG Journal Club | Scoop.it

Exercise is an effective treatment for depression, with walking or jogging, yoga, and strength training more effective than other exercises, particularly when intense. Yoga and strength training were well tolerated compared with other treatments. Exercise appeared equally effective for people with and without comorbidities and with different baseline levels of depression. To mitigate expectancy effects, future studies could aim to blind participants and staff. These forms of exercise could be considered alongside psychotherapy and antidepressants as core treatments for depression.

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February 8, 2024 2:42 PM
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The Beers Criteria then and now - Rochon - 2024 - Journal of the American Geriatrics Society - Wiley Online Library

The Beers Criteria then and now - Rochon - 2024 - Journal of the American Geriatrics Society - Wiley Online Library | Geriatría HGG Journal Club | Scoop.it

Over the past more than three decades, the Beers criteria have resonated deeply with clinicians and researchers. They have evolved in terms of the older adults that they apply to, the depth of leadership of the initiative, and the methodology being used. Yet, they have remained consistent in their intent, which is to improve the way we prescribe for older adults. In so doing, the Beers criteria have earned their place as a “household word” in American geriatric medicine.

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February 2, 2024 12:53 PM
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Why to test for dementia: perspectives of patients, significant others and general practitioners | Age and Ageing | Oxford Academic

Why to test for dementia: perspectives of patients, significant others and general practitioners | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Decision-making on diagnostic testing for dementia is a multifactorial and preference-guided process for all involved stakeholders, but decisions are often not explicitly jointly made. Development of patient decision aids could facilitate better involvement and more informed choices by patients.

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February 2, 2024 12:50 PM
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What are the priorities for research of older people living in their own home, including those living with frailty? A systematic review and content analysis of studies reporting older people’s prio...

What are the priorities for research of older people living in their own home, including those living with frailty? A systematic review and content analysis of studies reporting older people’s prio... | Geriatría HGG Journal Club | Scoop.it

There is limited evidence regarding the needs of older people, including those living with frailty, to inform research priority setting.Obje

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February 2, 2024 12:41 PM
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Reducing patient and planetary harms from high anticholinergic burden medication | The BMJ

Reducing patient and planetary harms from high anticholinergic burden medication | The BMJ | Geriatría HGG Journal Club | Scoop.it

What you need to know

  • Prescribing medicines with high anticholinergic burden carries significant risk of adverse clinical outcomes for patients

  • Anticholinergic burden scores can be a useful way of assessing anticholinergic burden

  • Consider tapering when stopping anticholinergic medications to avoid withdrawal effects, which may include nausea and sweating

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