Geriatría HGG Journal Club
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July 1, 2024 7:50 AM
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Motoric Cognitive Risk Syndrome and the Risk of Incident Dementia: A Systematic Review and Meta-Analysis of Cohort Studies | Gerontology

Motoric Cognitive Risk Syndrome and the Risk of Incident Dementia: A Systematic Review and Meta-Analysis of Cohort Studies | Gerontology | Geriatría HGG Journal Club | Scoop.it

Epidemiologic studies have indicated an association of motoric cognitive risk syndrome (MCR), a pre-dementia stage characterized by the presence of cognitive complaints and a slow gait, with increased risk of incident dementia.

 

Our results confirm that MCR is an independent risk factor of incident all-cause dementia and AD. Future studies are needed to better understand the mechanisms underlying this association.

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July 1, 2024 7:02 AM
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Association of the Drug Burden Index (DBI) exposure with outcomes: A systematic review - Liu - 2024 - Journal of the American Geriatrics Society - Wiley Online Library

Association of the Drug Burden Index (DBI) exposure with outcomes: A systematic review - Liu - 2024 - Journal of the American Geriatrics Society - Wiley Online Library | Geriatría HGG Journal Club | Scoop.it

A higher DBI may be associated with an increased risk of falls and decreased function and cognition. Higher DBI was inconsistently associated with increased mortality, length of stay, frailty, hospitalization or reduced quality of life. Human observational findings with respect to functional outcomes are supported by preclinical interventional studies. The DBI may be used as a tool to identify older adults at higher risk of harm.

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July 1, 2024 3:37 AM
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New Horizons in Peripheral Artery Disease | Age and Ageing | Oxford Academic

New Horizons in Peripheral Artery Disease | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Despite advances in minimally invasive revascularisation techniques and reduction in amputation incidence, survival remains poor for many with CLTI. Shared decision-making is essential, and conservative management is often appropriate for older patients. There is emerging evidence of the benefit of specialist geriatric team input in the perioperative management of older patients undergoing surgery for CLTI. Recent UK guidelines now recommend screening for frailty, cognitive impairment and delirium in older vascular surgery patients as well as recommending all vascular surgery services have support and input from specialist geriatrics teams.

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June 23, 2024 11:51 AM
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Persistent physical symptoms: definition, genesis, and management

Persistent physical symptoms (synonymous with persistent somatic symptoms) is an umbrella term for distressing somatic complaints that last several months or more, regardless of their cause. These symptoms are associated with substantial disability and represent a major burden for patients, health-care professionals, and society. Persistent physical symptoms can follow infections, injuries, medical diseases, stressful life events, or arise de novo. As symptoms persist, their link to clearly identifiable pathophysiology often weakens, making diagnosis and treatment challenging.

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June 23, 2024 11:36 AM
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Conveying Risks of Harm in Alzheimer Disease by Amyloid Lowering | Genetics and Genomics | JAMA | JAMA Network

Conveying Risks of Harm in Alzheimer Disease by Amyloid Lowering | Genetics and Genomics | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it
This Viewpoint discusses how data gaps in published research impede clinicians’ ability to clearly discuss the risks and benefits of amyloid-lowering drugs for treating Alzheimer disease.
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June 23, 2024 11:31 AM
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Antipsychotics for Dementia Tied to More Serious Harms Than Expected | Psychiatry and Behavioral Health | JAMA | JAMA Network

Antipsychotics for Dementia Tied to More Serious Harms Than Expected | Psychiatry and Behavioral Health | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it

Prior research has suggested that antipsychotic drugs might be overprescribed for people with dementia, despite known risks of stroke and sudden cardiac death. Now, findings from a new study in The BMJ indicate that the range of serious adverse outcomes associated with antipsychotics in these patients might be broader than previously thought.

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June 23, 2024 11:19 AM
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Study: Roughly 1 in 8 Patients Wrongly Diagnosed With Pneumonia | Infectious Diseases | JAMA | JAMA Network

Study: Roughly 1 in 8 Patients Wrongly Diagnosed With Pneumonia | Infectious Diseases | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it
About 12% of patients were inappropriately diagnosed with community-acquired pneumonia (CAP), according to results from more than 17 000 hospitalized patients across 48 hospitals in Michigan. Older people as well as those with dementia or altered mental status were at particularly high risk o
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June 23, 2024 10:50 AM
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Diets | New England Journal of Medicine

The ways in which particular variations in diet influence health and the course of disease remain largely undefined. The authors review the spectrum of types of diet and describe some attribute
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June 23, 2024 10:49 AM
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Cognition and Memory after Covid-19 in a Large Community Sample | New England Journal of Medicine

Cognition and Memory after Covid-19 in a Large Community Sample | New England Journal of Medicine | Geriatría HGG Journal Club | Scoop.it
To the Editor: Hampshire et al. (Feb. 29 issue)1 report that in a large cohort of adults living in the United Kingdom, participants with persisting symptoms after Covid-19 apparently had mor
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April 25, 2024 4:09 AM
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epidemiology of dying within 48 hours of presentation to emergency departments: a retrospective cohort study of older people across Australia and New Zealand | Age and Ageing | Oxford Academic

epidemiology of dying within 48 hours of presentation to emergency departments: a retrospective cohort study of older people across Australia and New Zealand | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it
AbstractBackground. Emergency department (ED) clinicians are more frequently providing care, including end-of-life care, to older people.Objectives. To est
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April 25, 2024 3:58 AM
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Frailty screening in the Emergency Department: why does it matter? | Age and Ageing | Oxford Academic

Frailty screening in the Emergency Department: why does it matter? | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Even in the UK National Health Service where emergency care administration of the Clinical Frailty Scale (CFS) is mandated, access to acute geriatrics services is often operationalised using site-specific definitions based on age thresholds, receipt of community care, manifestation of ‘geriatric giants’ or alternative frailty scores.

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April 25, 2024 3:17 AM
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Multiple adverse outcomes associated with antipsychotic use in people with dementia: population based matched cohort study | The BMJ

Multiple adverse outcomes associated with antipsychotic use in people with dementia: population based matched cohort study | The BMJ | Geriatría HGG Journal Club | Scoop.it
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April 10, 2024 3:07 AM
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Agreement of Antipsychotic Use between Nursing Home Electronic Records and Minimum Data Set

Agreement of Antipsychotic Use between Nursing Home Electronic Records and Minimum Data Set | Geriatría HGG Journal Club | Scoop.it

Nursing home (NH) Minimum Data Set (MDS) have frequently been used to measure medication use in epidemiologic studies, but there is little evidence on the accuracy of MDS-based medication records. We compared antipsychotic use estimated using 2 data sources—MDS and NH electronic medication administration records (eMAR).

 

Agreement between the MDS and eMAR in antipsychotic use is high, suggesting that the MDS is a valid tool to measure antipsychotic use in epidemiologic studies. Further studies with large and diverse populations are warranted to confirm our findings.

 

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July 1, 2024 7:26 AM
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Frailty as an upstream target for intervention: A unifying approach to intervening in the trajectories of health, function, and disease in late life - Callahan - 2024 - Journal of the American Geri...

Frailty as an upstream target for intervention: A unifying approach to intervening in the trajectories of health, function, and disease in late life - Callahan - 2024 - Journal of the American Geri... | Geriatría HGG Journal Club | Scoop.it

For clinical work, it remains vitally important to minimize the impact of precipitants to avoid further declines in function and independence. This study, and similar work, highlight how a frailty metric may identify a subset of the most vulnerable individuals for whom to target preventive measures. Most importantly, it is time to (a) categorize risk when enrolling populations and stratify by frailty; (b) consider composite outcomes for geriatric syndromes such as falls, delirium, and even phenotypic frailty, as a final common pathway after a precipitating event; and (c) further interrogate the inter-relationship of cognition, function, and physiological change as all part of soon-to-be modifiable hallmarks of accelerated biological aging.

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July 1, 2024 3:45 AM
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Guideline Recommendations on Behavioral and Psychological Symptoms of Dementia: A Systematic Review

Guideline Recommendations on Behavioral and Psychological Symptoms of Dementia: A Systematic Review | Geriatría HGG Journal Club | Scoop.it
There are several moderate to high-quality clinical practice guidelines making recommendations on BPSD assessment and management, but variability in recommendation statements across guidelines and insufficient consideration of guideline applicability may hamper guideline dissemination and implementation in clinical practice.
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July 1, 2024 3:36 AM
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Older people’s goals of care in relation to frailty status—the COOP-study | Age and Ageing | Oxford Academic

Older people’s goals of care in relation to frailty status—the COOP-study | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Preferred goals of care are not related to frailty status, while the importance ascribed to individual goals is slightly lower with higher frailty status. Future research should prioritise outcomes related to the shared goals of fit, mildly frail and severely frail older people to improve personalised medicine for older patients.

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June 23, 2024 11:46 AM
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Findings from the Global Burden of Disease Study 2021

In The Lancet, we have published the findings of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 in a series of six Articles.1–6 GBD began in 1991 and has continued over the past three decades to provide a comprehensive empirical
assessment of health around the world.7 With each iteration GBD has become more detailed, including more causes, risks, and locations, improving granularity of age group analyses, and has enabled the completion of extension studies, such as forecasting studies and estimations of the burden of antimicrobial resistance.

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June 23, 2024 11:32 AM
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CMS Finalizes Staffing Minimum Requirements for Nursing Homes | Geriatrics | JAMA | JAMA Network

CMS Finalizes Staffing Minimum Requirements for Nursing Homes | Geriatrics | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it

The US Centers for Medicare & Medicaid Services (CMS) recently finalized a rule establishing the first minimum staffing requirements for nursing homes after an earlier version was proposed last September. The new rule will “hold nursing homes accountable for providing safe and high-quality care” for the 1.2 million people who are cared for in Medicare- and Medicaid-certified long-term care facilities, the agency announced.

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June 23, 2024 11:24 AM
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Interstitial Lung Disease: A Review | Pulmonary Medicine | JAMA | JAMA Network

Interstitial Lung Disease: A Review | Pulmonary Medicine | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it
This review summarizes current evidence regarding the diagnosis and treatment of interstitial lung disease.
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June 23, 2024 11:16 AM
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Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes | Geriatrics | JAMA | JAMA Network

Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes | Geriatrics | JAMA | JAMA Network | Geriatría HGG Journal Club | Scoop.it
This quality improvement study evaluates whether implementation of a decolonization collaborative is associated with reduced regional multidrug-resistant organism prevalence, incident clinical cultures, infection-related hospitalizations, costs, and deaths.
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June 23, 2024 10:50 AM
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Early Diagnosis and Treatment of COPD and Asthma — A Randomized, Controlled Trial | New England Journal of Medicine

Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated.We used a case-finding method t
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June 23, 2024 10:48 AM
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Magnesium Disorders | New England Journal of Medicine

This review focuses on recent discoveries in how magnesium functions in the body, concentrating on hypomagnesemia, the most common clinical magnesium disorder. Hypermagnesemia is rare and see
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April 25, 2024 3:59 AM
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Frailty same day emergency care (SDEC): a novel service model or an unhelpful distraction? | Age and Ageing | Oxford Academic

Frailty same day emergency care (SDEC): a novel service model or an unhelpful distraction? | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it

Perhaps a more pressing issue is to discuss whether the perpetual search for bed-day savings is distracting from what should be the primary focus of a healthcare system, namely, to improve patient outcomes. The emergence of pre-hospital triage schemes with access to ‘hospital at home’ and of single emergency care access points might help focus on getting the right care to the right person at the right time. Perhaps it is time for an honest conversation about moving away from heroic efforts to save bed-days, and start to focus upon what really matters to patients. We certainly do not have the right solutions at present

Servicio de Geriatría's insight:

"Evitar el ingreso hospitalario" versus "Proveer la atención necesaria en el momento y lugar adecuados"

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April 25, 2024 3:57 AM
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Zoledronate for hip fractures: the road towards achieving consensus | Age and Ageing | Oxford Academic

Zoledronate for hip fractures: the road towards achieving consensus | Age and Ageing | Oxford Academic | Geriatría HGG Journal Club | Scoop.it
Hip fractures confer a much higher re-fracture risk compared with other appendicular fractures [1]. This re-fracture risk peaks 18 months after the initial
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April 10, 2024 3:08 AM
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Improving Handoffs After Osteoporotic Fractures

Improving Handoffs After Osteoporotic Fractures | Geriatría HGG Journal Club | Scoop.it

Osteoporotic fractures among long-term care residents have substantial economic and human costs. After a fracture, many older adults do not receive an osteoporosis diagnosis or evidence-based treatment, which leads to increased risk of recurrent fractures. Optimal processes are well defined for transitioning medical care after a hip or vertebral fracture for osteoporosis evaluation, but the handoff process from the specialist back to a primary care practitioner (PCP) or to a rehabilitative setting is not well defined.

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