Genetics - GEG Tech top picks
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Scooped by BigField GEG Tech
February 3, 2014 4:21 AM
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The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution

The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution | Genetics - GEG Tech top picks | Scoop.it

https://www.sciencemag.org/content/342/6164/1242592.abstract

BigField GEG Tech's insight:

Surprising discovery about the earliest diverging animal lineage.
Our most distant cousin is not Placozoa or Porifera (sponges) but Ctenophora!

 

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Scooped by BigField GEG Tech
April 8, 2014 6:12 AM
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Low copy number of the salivary amylase gene predisposes to obesity - Nature Genetics

Low copy number of the salivary amylase gene predisposes to obesity - Nature Genetics | Genetics - GEG Tech top picks | Scoop.it

A surprising path about predispositions to obesity

BigField GEG Tech's insight:

A surprising path about predispositions to obesity

 

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Scooped by BigField GEG Tech
December 9, 2013 6:13 AM
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The Burmese python genome reveals the molecular basis for extreme adaptation in snakes

The Burmese python genome reveals the molecular basis for extreme adaptation in snakes | Genetics - GEG Tech top picks | Scoop.it
BigField GEG Tech's insight:

The surprising contribution of python to study the genetic mechanisms of adaptation.

 

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Scooped by BigField GEG Tech
December 6, 2013 4:39 AM
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Oldest Human DNA Contains Clues to Mysterious Species

Oldest Human DNA Contains Clues to Mysterious Species | Genetics - GEG Tech top picks | Scoop.it
Find sheds light on relationship between elusive "Denisovans" and Neandertals
BigField GEG Tech's insight:

New record! Until now, the oldest human genome previously sequenced was aged of 70.000 to 80.000 years. Recently, Juan-Luis Arsuaga & al. have extracted and analyzed human DNA which is 400.000 years old.  These investigations will provide certainly valuable data to better understand the Human phylogeny.

 

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Scooped by BigField GEG Tech
December 5, 2013 9:08 AM
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Epigenetics, vitamin supplements and cellular reprogramming

Epigenetics, vitamin supplements and cellular reprogramming | Genetics - GEG Tech top picks | Scoop.it
BigField GEG Tech's insight:

An interesting link between the vitamin C and the reprogramming of somatic cells to pluripotency.

 

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BigField GEG Tech's curator insight, December 5, 2013 8:58 AM

An interesting link between the vitamin C and the reprogramming of somatic cells to pluripotency.

 

http://geg-tech.com

 

Scooped by BigField GEG Tech
December 5, 2013 9:06 AM
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Faces are sculpted by 'junk DNA'

Faces are sculpted by 'junk DNA' | Genetics - GEG Tech top picks | Scoop.it
Scientists have identified thousands of regions in the genome that control the activity of genes for facial features
BigField GEG Tech's insight:

Another example of the complexity of gene interactions and regulations. More than 4,000 candidate enhancer sequences predicted to be active in the developing craniofacial complex!

 

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Rescooped by BigField GEG Tech from Mobile Genetic Elements
January 21, 2014 4:56 AM
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Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia

Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia | Genetics - GEG Tech top picks | Scoop.it

L1 retrotransposons are particularly active in the cerebellum (shown in purple), which plays an important role in motor control. Green dots represent brain cells with new L1 insertions.


Via THE_inteins
BigField GEG Tech's insight:

A link between Schizophrenia and L1 retrotransposition, interesting!

 

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Scooped by BigField GEG Tech
January 20, 2014 10:36 AM
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Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model : Nature Genetics : Nature Publishing Group

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model : Nature Genetics : Nature Publishing Group | Genetics - GEG Tech top picks | Scoop.it
Neal Copeland and colleagues use a transposon mutagenesis screen to identify drivers of hepatocellular carcinoma in a mouse model of chronic hepatitis B infection.
BigField GEG Tech's insight:

Smart use of transposon to better characterize hepatocellular carcinoma.

 

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Rescooped by BigField GEG Tech from Genetic Engineering Publications - GEG Tech top picks
December 9, 2013 5:29 AM
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Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model | Genetics - GEG Tech top picks | Scoop.it

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2847.html

BigField GEG Tech's insight:

An original use of a transposon to better understand the hepatocarcinoma mechanisms.

 

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BigField GEG Tech's curator insight, December 9, 2013 4:25 AM

An original use of a transposon to better understand the hepatocarcinoma mechanisms.

 

http://geg-tech.com

 

 

Rescooped by BigField GEG Tech from Genetics - GEG Tech top picks
December 5, 2013 9:38 AM
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Fine Tuning of Facial Morphology with Enhancers

Gene disruptions that cause the severe dysmorphologies like cleft palate are one thing, but what causes the subtle shifts in facial morphology that make each...

Via BigField GEG Tech
BigField GEG Tech's insight:

http://geg-tech.com

BigField GEG Tech's curator insight, December 5, 2013 9:07 AM

A really good video provided by the scientists who performed the work related to the scoop “Faces are sculpted by junk DNA”.

 

http://geg-tech.com

Scooped by BigField GEG Tech
December 5, 2013 9:07 AM
Scoop.it!

Fine Tuning of Facial Morphology with Enhancers

Gene disruptions that cause the severe dysmorphologies like cleft palate are one thing, but what causes the subtle shifts in facial morphology that make each...
BigField GEG Tech's insight:

A really good video provided by the scientists who performed the work related to the scoop “Faces are sculpted by junk DNA”.

 

http://geg-tech.com