GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK
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Multimodal biomedical AI | Nature Medicine

Multimodal biomedical AI | Nature Medicine | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
The increasing availability of biomedical data from large biobanks, electronic health records, medical imaging, wearable and ambient biosensors, and the lower cost of genome and microbiome sequencing have set the stage for the development of multimodal artificial intelligence solutions that capture the complexity of human health and disease. In this Review, we outline the key applications enabled, along with the technical and analytical challenges. We explore opportunities in personalized medicine, digital clinical trials, remote monitoring and care, pandemic surveillance, digital twin technology and virtual health assistants. Further, we survey the data, modeling and privacy challenges that must be overcome to realize the full potential of multimodal artificial intelligence in health. Multimodal artificial intelligence models could unlock many exciting applications in health and medicine; this Review outlines the most promising uses and the technical pitfalls to avoid.
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Hong Kong health service leverages world's first retinal imaging AI for Alzheimer's detection

Hong Kong health service leverages world's first retinal imaging AI for Alzheimer's detection | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
The AI, trained on around 13,000 fundus images from over 600 Alzheimer's patients, has demonstrated up to 92% accuracy.

Via Emmanuel Capitaine
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AI agent shows promise to support oncologists in everyday clinical practice

AI agent shows promise to support oncologists in everyday clinical practice | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Clinical decision-making in oncology is challenging and requires the analysis of various data types – from medical imaging and genetic information to patient records and treatment guidelines.

Via Emmanuel Capitaine
Richard Platt's curator insight, Today, 10:42 AM

Clinical decision-making in oncology is challenging and requires the analysis of various data types – from medical imaging and genetic information to patient records and treatment guidelines.

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The Behavioral Health AI Boom Is Real. So Are the Risks

The Behavioral Health AI Boom Is Real. So Are the Risks | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Behavioral health doesn’t need tech that replaces people. It needs technology that respects them, amplifying what clinicians do best and helping more people get the care they deserve.

Via Emmanuel Capitaine
Richard Platt's curator insight, June 6, 10:16 PM

 Behavioral health doesn’t need tech that replaces people. It needs technology that respects them, amplifying what clinicians do best and helping more people get the care they deserve.

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FaceAge AI Tool Surpasses Doctors with 81% Accuracy in Cancer Survival Prediction

FaceAge AI Tool Surpasses Doctors with 81% Accuracy in Cancer Survival Prediction | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it

Via Richard Platt
Richard Platt's curator insight, June 4, 3:39 PM

FaceAge, a face-reading AI tool that estimates biological age from facial photographs, predicts cancer outcomes with an impressive 81% accuracy rate. This surpasses traditional methods and outperforms doctors in survival assessments. Developed by researchers at Mass General Brigham, FaceAge shows early promise in predicting short-term life expectancy. The findings suggest the AI tool can identify high-risk patients and provide a low-cost, accessible way to inform care decisions, enhancing clinical decision-making.

This improvement was observed across multiple cancer types and stages, with FaceAge delivering a reliable prognostic signal, offering doctors more objective and precise survival estimates. FaceAge has drawn a mix of cautious optimism and concern from medical experts. Irbaz Riaz, assistant professor of medicine and artificial intelligence consultant at Mayo Clinic, called it “a promising early-stage tool.”  Hugo Aerts, director of the AI in Medicine program at Mass General Brigham and a lead researcher on the tool, acknowledged its potential benefits but warned it could also cause harm if misused. He stressed that hospitals have strict rules and oversight to ensure AI is used properly and only to benefit patients, not insurers or other parties. -- Researchers say more studies are needed before FaceAge can be routinely used in clinical settings. Their goal is to turn it into an early detection system for various health issues, supported by strong ethical and regulatory standards.

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A clinical certification pathway for generalist medical AI systems

There have been extensive evaluations of artificial intelligence (AI) systems for
narrow medical tasks, but more work is needed to systematically evaluate and deploy
AI systems that can perform a broad range of medical tasks. The medical training process
itself might offer a template for addressing this challenge. Clinicians undergo rigorous
education and training, progressing through stages of increasing responsibility and
autonomy. Similarly, generalist medical AI systems could be subjected to a phased
certification model before they are granted greater autonomy in patient care.
Richard Platt's curator insight, May 27, 12:44 PM

There have been extensive evaluations of artificial intelligence (AI) systems for narrow medical tasks, but more work is needed to systematically evaluate and deploy AI systems that can perform a broad range of medical tasks. The medical training process itself might offer a template for addressing this challenge. Clinicians undergo rigorous education and training, progressing through stages of increasing responsibility and autonomy. Similarly, generalist medical AI systems could be subjected to a phased certification model before they are granted greater autonomy in patient care.

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Will AI Make the Electronic Health Record More Efficient for Clinicians?

Will AI Make the Electronic Health Record More Efficient for Clinicians? | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Electronic health records (EHRs) have become nearly universal in the United States, enhancing care coordination and patient access to health data. However, these advancements have introduce
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IA et IA générative : Milvue met l’intelligence de la technologie au service des praticiens grâce à Azure OpenAI Service et Azure AI Studio | Microsoft Customer Stories

IA et IA générative : Milvue met l’intelligence de la technologie au service des praticiens grâce à Azure OpenAI Service et Azure AI Studio | Microsoft Customer Stories | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
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OpenAI unveils HealthBench to evaluate LLMs' safety in healthcare

The offering measures AI's real-world performance and safety around handling realistic medical conversations, using physician-created rubrics and GPT-4.1 scoring.
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8 startups qui façonnent le secteur de la santé de demain

8 startups qui façonnent le secteur de la santé de demain | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Découvrez huit startups accompagnées par le Startup Program d’OVHcloud qui réinventent dès aujourd’hui les solutions de santé de demain
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A framework for considering the use of generative AI for health | npj Digital Medicine

A framework for considering the use of generative AI for health | npj Digital Medicine | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
This perspective provides a critical framework for evaluating the use of Generative AI (GenAI) in healthcare, informed by two roundtable events and a series of semi-structured expert interviews. By outlining key principles and risks—including mapping applications to GenAI strengths, ensuring rigorous evaluation frameworks, and fostering transparency and collaboration—it will support healthcare professionals and policymakers in navigating the ethical and impactful integration of GenAI into healthcare.
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AI listens for health conditions

AI listens for health conditions | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Voice recordings, examined by artificial intelligence, might provide new biomarkers for conditions such as heart disease and Alzheimer’s.
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Are Therapy-Bots Really Our Best Chance At Solving Population Mental Health?

Are Therapy-Bots Really Our Best Chance At Solving Population Mental Health? | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Like bandaids, AI chatbots can comfort us in times of desperation. But healing a wound takes more than a comforting bandaid.

Via Emmanuel Capitaine , Lionel Reichardt / le Pharmageek, Richard Platt
Richard Platt's curator insight, May 17, 2:22 PM

Like bandaids, AI chatbots can comfort us in times of desperation. But healing a wound takes more than a comforting bandaid.

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Why AI’s Biggest Impact In Health Could Be Reducing Doctors’ Paperwork

Why AI’s Biggest Impact In Health Could Be Reducing Doctors’ Paperwork | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
AI-powered start-ups such as ReportAId, which has raised $2.2 million of new funding, are focusing on the power of technology to reduce manual processes in healthcare...

Via Emmanuel Capitaine
Richard Platt's curator insight, May 17, 2:11 PM

 AI-powered start-ups such as ReportAId, which has raised $2.2 million of new funding, are focusing on the power of technology to reduce manual processes in healthcare...

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A systematic review of influences on engagement with remote health interventions targeting weight management for individuals living with excess weight | International Journal of Obesity

A systematic review of influences on engagement with remote health interventions targeting weight management for individuals living with excess weight | International Journal of Obesity | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Obesity rates are continually rising and remote weight management interventions appear to demonstrate feasible prospects. Previous reviews have investigated influential factors to engagement of such interventions in community settings; however, limited research has examined adults’ engagement in...

Via Emmanuel Capitaine
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Exploring the potential of digital biomarkers as a measure of brain health ‘capital’ | npj Digital Medicine

Exploring the potential of digital biomarkers as a measure of brain health ‘capital’ | npj Digital Medicine | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Neurological conditions, including dementia, pose a major public health challenge, contributing to a significant and growing clinical, economic, and societal burden. Traditionally, research and clinical practice have focused on diseases like dementia in isolation.

Via Emmanuel Capitaine
Richard Platt's curator insight, June 6, 10:18 PM

 Neurological conditions, including dementia, pose a major public health challenge, contributing to a significant and growing clinical, economic, and societal burden. Traditionally, research and clinical practice have focused on diseases like dementia in isolation.

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AI vs. Clinicians: New Study Compares Diagnostic Accuracy

AI vs. Clinicians: New Study Compares Diagnostic Accuracy | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
In a landmark comparative study published in the Journal of Health Organization and Management, researchers from the University of Maine have embarked on a rigorous investigation to evaluate the diagnostic capabilities of artificial intelligence (AI) models against those of seasoned human clinicians...

Via Emmanuel Capitaine
Richard Platt's curator insight, June 6, 10:18 PM

 In a landmark comparative study published in the Journal of Health Organization and Management, researchers from the University of Maine have embarked on a rigorous investigation to evaluate the diagnostic capabilities of artificial intelligence (AI) models against those of seasoned human clinicians.

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Prévention : 20 start-up dans les starting-blocks | Le Quotidien du Médecin | Santé & Société | eSanté

Prévention : 20 start-up dans les starting-blocks | Le Quotidien du Médecin | Santé & Société | eSanté | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Alors que 80 % des dépenses de santé sont dédiées au curatif, 3 % profitent à la prévention. Comment inverser la tendance ? « Pour accompagner le passage du curatif vers le préventif, nous savions que l’innovation allait jouer un très grand rôle. C’est pourquoi nous avons monté un “accélérateur prévention” », explique Chahra Louafi, directrice du fonds Patient autonomie de Bpifrance, partie prenante de ce programme d’accompagnement de start-up lancé en septembre 2024. Mi-mai, un bilan de la première promotion a été présenté au sein de PariSanté campus.
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Governing synthetic data in medical research: the time is now

Governing synthetic data in medical research: the time is now | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
The governance of generative artificial intelligence (AI) technologies in medicine
has become a major topic of discussion due to concerns about their rapid development
and use, which have outpaced existing regulatory measures.1 Findings from a recent
large-scale survey underscore the urgency of renewed oversight, revealing that one
(20%) in five of the UK-based general practitioners surveyed use large language model
(LLM) chatbots for clinical tasks.2 Although much attention has been focused on popular
and widely available LLM-based chatbots, such as ChatGPT (OpenAI and Microsoft), addressing
unresolved challenges related to privacy, bias, accuracy, and accountability requires
a standardised frameworks that goes beyond the regulation of chatbot as conversational
tools and considers the wider AI capabilities for data generation.
Richard Platt's curator insight, May 27, 12:48 PM

The governance of generative artificial intelligence (AI) technologies in medicine has become a major topic of discussion due to concerns about their rapid development and use, which have outpaced existing regulatory measures.

1 Findings from a recent large-scale survey underscore the urgency of renewed oversight, revealing that one in five (20%) of the UK-based general practitioners surveyed use large language model (LLM) chatbots for clinical tasks.

2 Although much attention has been focused on popular and widely available LLM-based chatbots, such as ChatGPT (OpenAI and Microsoft), addressing unresolved challenges related to privacy, bias, accuracy, and accountability requires a standardised framework that goes beyond the regulation of chatbots as conversational tools and considers the wider AI capabilities for data generation.

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Pourquoi les IA génératives entraînent une double discrimination - Harvard Business Review France

Pourquoi les IA génératives entraînent une double discrimination - Harvard Business Review France | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Il s'agit à la fois d'une discrimination de conception et d’usage.
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A systematic review of clinicians’ acceptance and use of clinical decision support systems over time | npj Digital Medicine

A systematic review of clinicians’ acceptance and use of clinical decision support systems over time | npj Digital Medicine | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Existing reviews have identified factors influencing Clinical Decision Support (CDS) adoption by clinicians in practice but overlook the dynamic and evolving nature of technology and users’ needs over time. This review aimed to identify factors that influence early, mid-term, and sustained acceptance and use of CDS in hospital settings. Five databases were searched from 2007 to January 2024 and 67 papers were included. Factors were extracted and synthesised according to the time that data were collected following CDS implementation. Factors relating to the CDS intervention (e.g. utility) and inner setting (e.g. fit with workflows) were reported across all time periods. Perceived outcomes were more often identified in the first year of use, and individual factors after the first 6 months of use. Strategies to work around CDS limitations were reported 5 years after implementation. Our review provides guidance for developing, implementing, and supporting ongoing use of CDS systems.
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FDA's plan to roll out AI agencywide raises questions

FDA's plan to roll out AI agencywide raises questions | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
This marks one of the most ambitious attempts yet to embed AI deep within a regulatory agency.
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La santé des Français : sortir de l’impasse | Terra Nova

La santé des Français : sortir de l’impasse | Terra Nova | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Alors que l’on célèbre cette année les 80 ans de la Sécurité sociale, les inquiétudes sur la soutenabilité de notre système de soins se multiplient. Le déficit de la branche maladie atteint un niveau record hors crise sanitaire, alors qu’un mur démographique et épidémiologique se profile à l’horizon. Les solutions purement comptables et les facilités de court terme ne permettront ni de résoudre l’équation financière ni de relever les défis qui se présentent. Un autre modèle est à inventer. Selon Nicolas Revel, il doit se construire autour d’une nouvelle organisation du suivi des pathologies chroniques et faire le pari de la qualité des soins comme vecteur essentiel d’attractivité pour les soignants et de maîtrise des dépenses de santé. Alors que l’on célèbre cette année les 80 ans de la Sécurité sociale, les inquiétudes sur la soutenabilité de notre système de soins se multiplient. Le déficit de la branche maladie atteint un niveau record hors crise sanitaire, alors qu’un mur démographique et épidémiologique se profile à l’horizon. Les solutions purement comptables et les facilités de court terme ne permettront ni de résoudre l’équation financière ni de relever les défis qui se présentent. Un autre modèle est à inventer. Selon Nicolas Revel, il doit se construire autour de la problématique des pathologies chroniques et faire le pari de la qualité des soins comme vecteur essentiel d’attractivité pour les soignants et de maîtrise des dépenses de santé.
Lionel Reichardt / le Pharmageek's insight:

### Résumé
L'article explore les défis majeurs auxquels le système de santé français est confronté, notamment le vieillissement de la population, l'augmentation des pathologies chroniques et les déficits structurels. Il propose des solutions pour réformer le système, améliorer la qualité des soins, renforcer la prévention et transformer le suivi des pathologies chroniques. L'accent est mis sur la nécessité d'une approche coordonnée, d'une meilleure organisation des soins et d'une stratégie durable pour garantir l'efficacité et la soutenabilité du système de santé.

### Points Clés
- Terra Nova est un think tank progressiste indépendant visant à produire des solutions politiques innovantes en France et en Europe.
- Le déficit de la branche maladie atteint un niveau record et nécessite un nouveau modèle centré sur la qualité des soins et une meilleure organisation des pathologies chroniques.
- La population vieillissante et l'augmentation des maladies chroniques posent des défis démographiques et épidémiologiques majeurs.
- Le système de santé français consomme une part importante du PIB mais reste critiqué pour l'accès aux soins et les conditions de travail des soignants.
- Il y a une insuffisance de professionnels de santé en France, aggravée par des tensions territoriales et disciplinaires.
- Former plus de médecins n'est pas suffisant ; il faut aussi améliorer les conditions de travail et promouvoir la délégation de tâches.
- Des consultations avancées dans les zones sous-denses pourraient améliorer l'accès aux soins.
- La régulation économique du système de santé doit éviter les solutions comptables à court terme et se concentrer sur la qualité des soins.
- Les dépenses inutiles ou évitables représentent une part importante des coûts de santé et nécessitent des actions ciblées pour améliorer la qualité et la pertinence des soins.
- La prévention (primaire, secondaire, tertiaire) est sous-développée en France, ce qui engendre des coûts évitables.
- Le suivi des pathologies chroniques est insuffisant, entraînant des hospitalisations évitables et des coûts élevés.
- Des modèles innovants comme les CECICS montrent des résultats prometteurs pour la gestion des pathologies chroniques et pourraient être élargis.
- Une réforme du financement des soins est nécessaire pour favoriser la coordination et éviter les hospitalisations inutiles.
- Une transformation stratégique durable et coordonnée est essentielle pour garantir la soutenabilité du système de santé.

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E-santé : la ruée vers l'or (numérique) a bien lieu..mais sans vous ? Ce genre d'article me laisse perplexe... et vous?

E-santé : la ruée vers l'or (numérique) a bien lieu..mais sans vous ? Ce genre d'article me laisse perplexe... et vous? | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
Les investisseurs affluent, les fonds se multiplient, les deals s'enchaînent. Pourtant, beaucoup d'entrepreneurs français passent encore à côté.
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Avec son benchmark HealthBench, OpenAI s'attaque à l'évaluation des LLM dans la santé

Avec son benchmark HealthBench, OpenAI s'attaque à l'évaluation des LLM dans la santé | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it

HealthBench doit aider dans l'évaluation de la sécurité et des performances des grands modèles de langage dans le domaine de la santé. En...-IA générative
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Taiwanese AI company obtains 510(k) for video-based respiratory rate gauge

Taiwanese AI company obtains 510(k) for video-based respiratory rate gauge | GAFAMS, STARTUPS & INNOVATION IN HEALTHCARE by PHARMAGEEK | Scoop.it
This follows the clearance for heart rate measurement on the FaceHeart mobile app in 2023.

Via Emmanuel Capitaine
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