Allergy (and clinical immunology)
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Allergy (and clinical immunology)
Ressources et Actualités pour la spécialité Allergie
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Scooped by Gilbert C FAURE
January 28, 2016 3:23 PM
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Clinical and Translational Allergy | Full text | Incidence and risk factors for food hypersensitivity in UK infants: results from a birth cohort study

The prevalence of food hypersensitivity in the UK is still largely open to debate. Additionally its pathogenesis is also unclear although it is known that there are differing phenotypes.

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Results

Cumulative incidence of food hypersensitivity by 2 years of age was 5.0 %. The cumulative incidence for individual food allergens were hens’ egg 2.7 % (1.6–3.8); cows’ milk 2.4 % (1.4–3.5); peanut 0.7 % (0.1–1.3); soy 0.4 % (0.0–0.8); wheat 0.2 % (0.0–0.5) and 0.1 % (0.0–0.32) for fish. The cumulative incidence of IgE-mediated food allergy was 2.6 % with 2.1 % reacting to hens’ egg. For non-IgE-mediated food allergy the cumulative incidence was 2.4 % (cows’ milk 1.7 %). Predictors for any food hypersensitivity were wheeze, maternal atopy, increasing gestational age, age at first solid food introduction and mean healthy dietary pattern score. Predictors for IgE mediated allergy were eczema, rhinitis and healthy dietary pattern score whereas for non-IgE-mediated food allergy the predictors were dog in the home, healthy dietary pattern score, maternal consumption of probiotics during breastfeeding and age at first solid food introduction.

Conclusions

Just under half the infants with confirmed food hypersensitivity had no demonstrable IgE. In an exploratory analysis, risk factors for this phenotype of food hypersensitivity differed from those for IgE-mediated food allergy except for a healthy infant diet which was associated with less risk for both phenotypes.

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Scooped by Gilbert C FAURE
January 20, 2016 9:13 AM
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Detection of specific immunoglobulin E antibodies toward common airborne allergens, peanut, wheat, and latex in solvent/detergent-treated pooled pl... - PubMed - NCBI

Detection of specific immunoglobulin E antibodies toward common airborne allergens, peanut, wheat, and latex in solvent/detergent-treated pooled pl... - PubMed - NCBI | Allergy (and clinical immunology) | Scoop.it

Transfusion. 2016 Jan 18. doi: 10.1111/trf.13451. [Epub ahead of print]

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Scooped by Gilbert C FAURE
August 13, 2015 4:57 AM
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Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants - Annals of Allergy, Asthma & Immunology

Avoid #peanut_allergy by introducing #peanuts into an infants diet early, rather than later.. http://t.co/CUh84IMZN8
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Scooped by Gilbert C FAURE
June 24, 2015 12:18 PM
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Peanut allergy drug slated for 2018 debut

Peanut allergy drug slated for 2018 debut | Allergy (and clinical immunology) | Scoop.it
A small French biopharmaceutical company has developed a new patch to help allergy sufferers increase their peanut tolerance.
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Scooped by Gilbert C FAURE
April 16, 2015 12:31 PM
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A gut microbe that stops food allergies

A gut microbe that stops food allergies | Allergy (and clinical immunology) | Scoop.it
Giving mice common intestinal bacteria eliminated peanut allergies
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Scooped by Gilbert C FAURE
April 11, 2015 4:32 AM
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Development of a Novel Strategy to Isolate Lipophilic Allergens (Oleosins) from Peanuts

Development of a Novel Strategy to Isolate Lipophilic Allergens (Oleosins) from Peanuts | Allergy (and clinical immunology) | Scoop.it
by Christian Schwager, Skadi Kull, Susanne Krause, Frauke Schocker, Arnd Petersen, Wolf-Meinhard Becker, Uta Jappe
Background Peanut allergy is one of the most severe class I food allergies with increasing prevalence.
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Scooped by Gilbert C FAURE
March 6, 2015 5:40 AM
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NEJM — Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy

NEJM — Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy | Allergy (and clinical immunology) | Scoop.it
Original Article from The New England Journal of Medicine — Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy
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Scooped by Gilbert C FAURE
March 2, 2015 9:28 AM
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Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy — NEJM

Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy — NEJM | Allergy (and clinical immunology) | Scoop.it
Original Article from The New England Journal of Medicine — Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy
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Scooped by Gilbert C FAURE
February 21, 2015 1:42 PM
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Peanut allergies and emerging trends: Review of science and public policy - Journalist's Resource

Peanut allergies and emerging trends: Review of science and public policy - Journalist's Resource | Allergy (and clinical immunology) | Scoop.it
2015 review of recent research and relevant data that can help put peanut and food allergies in context, with a look at medical facts and trends relating to regulation.
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Rescooped by Gilbert C FAURE from ReactNow - Latest News updated around the clock
January 29, 2015 8:14 AM
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Peanut allergy researchers say they may have found key to a cure

Peanut allergy researchers say they may have found key to a cure | Allergy (and clinical immunology) | Scoop.it
Melbourne-based study of children given nut protein with probiotic has transformed the lives of 80% of those who took part in clinical trial

Via ReactNow
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Scooped by Gilbert C FAURE
January 9, 2015 9:24 AM
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Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut - Journal of Allergy and Clinical Immunology

RT @GoAllergy: Editors choice! Well done @alex_fsantos Use of BAT in predicting dose & severity of peanut reactions. http://t.co/AR3JvwhE70
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Scooped by Gilbert C FAURE
December 3, 2014 8:45 AM
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Peanut Allergy Patch Quest Has French Company Spurning Suitors - Bloomberg

Peanut Allergy Patch Quest Has French Company Spurning Suitors - Bloomberg | Allergy (and clinical immunology) | Scoop.it
DBV Technologies SA has drawn suitors after its peanut allergy patch showed positive results in early tests. The company is spurning advances because it wants to go it alone.
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Scooped by Gilbert C FAURE
November 10, 2014 2:55 PM
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Ultrasensitive peanut allergy test - Royal Society of Chemistry

Ultrasensitive peanut allergy test - Royal Society of Chemistry | Allergy (and clinical immunology) | Scoop.it
Immunoassay recognises immunoglobulins for both peptide and carbohydrate epitopes
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Scooped by Gilbert C FAURE
January 24, 2016 3:56 AM
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Immunotherapy using algal-produced Ara h 1 core domain suppresses peanut allergy in mice - Gregory - 2015 - Plant Biotechnology Journal - Wiley Online Library

Immunotherapy using algal-produced Ara h 1 core domain suppresses peanut allergy in mice - Gregory - 2015 - Plant Biotechnology Journal - Wiley Online Library | Allergy (and clinical immunology) | Scoop.it

Peanut allergy is an IgE-mediated adverse reaction to a subset of proteins found in peanuts. Immunotherapy aims to desensitize allergic patients through repeated and escalating exposures for several months to years using extracts or flours.

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Scooped by Gilbert C FAURE
January 8, 2016 11:17 AM
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Practice Guidelines: Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants: Consensus Communication - American Family Physician

This consensus communication focuses on new data that support introducing peanuts early in infants, and it aims to assist with decisions about introduction; it can be used for guidance while formal guidelines are being developed.

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Scooped by Gilbert C FAURE
July 24, 2015 5:35 AM
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US investors invest $281.5m in French allergy play - European Biotechnology News - European Biotechnology News

US investors invest $281.5m in French allergy play - European Biotechnology News - European Biotechnology News | Allergy (and clinical immunology) | Scoop.it
US money keeps flowing into Europe's biotechs. As the race for the peanut allergy market heats up, NASDAQ listed French biotech DBV has announced the successful closing of US$281m (€256m) share offering for its allergy products.
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Scooped by Gilbert C FAURE
June 16, 2015 2:51 PM
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Results of New Peanut Allergy Trials Presented at EAACI Meeting

Results of New Peanut Allergy Trials Presented at EAACI Meeting | Allergy (and clinical immunology) | Scoop.it
The European Academy of Allergy and Clinical Immunology (EAACI) recently held its 2015 Annual Congress in Barcelona, Spain. FARE CEO Dr. James R. Baker, Jr. and FARE SVP of Research and Operations ...
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Scooped by Gilbert C FAURE
April 14, 2015 2:02 PM
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FDA grants breakthrough designation for Viaskin Peanut in children

FDA grants breakthrough designation for Viaskin Peanut in children | Allergy (and clinical immunology) | Scoop.it
The FDA granted breakthrough therapy designation to Viaskin Peanut, an epicutaneous delivery system, for the treatment of children aged 6 to 11 years with peanut allergy, according to a manufacturer’s press release.The Viaskin Peanut (DBV Technologies)...
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Scooped by Gilbert C FAURE
April 10, 2015 3:45 PM
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A Patch for Peanut Allergies

A Patch for Peanut Allergies | Allergy (and clinical immunology) | Scoop.it
French biopharmaceutical company DBV Technologies moves closer to bringing its peanut allergy patch to market, receiving Breakthrough Therapy Designation from the U.S. Food and Drug Administration as it prepares to launch its Phase 3 trial.
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Scooped by Gilbert C FAURE
March 4, 2015 2:12 PM
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Late-Breaking Peanut Patch Phase IIb Trial Results Unveiled at AAAAI Annual Meeting

Late-Breaking Peanut Patch Phase IIb Trial Results Unveiled at AAAAI Annual Meeting | Allergy (and clinical immunology) | Scoop.it
From BioPortfolio: Epicutaneous Immunotherapy (EPIT) introduces new way to treat peanut allergies Houston, TX (PRWEB) February 22, 2015 A team of researchers unveiled the results ...
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Scooped by Gilbert C FAURE
February 28, 2015 12:11 PM
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Peanut allergy 'cut by early exposure'

Peanut allergy 'cut by early exposure' | Allergy (and clinical immunology) | Scoop.it
Eating peanut products as a baby dramatically cuts the risk of allergy, a study suggests.
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Rescooped by Gilbert C FAURE from Physical and Mental Health - Exercise, Fitness and Activity
January 29, 2015 8:15 AM
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Potential peanut allergy cure

Potential peanut allergy cure | Allergy (and clinical immunology) | Scoop.it
Clinical trial transforms the lives of 80 per cent of young participants with potentially fatal allergies.

Via Peter Mellow
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Scooped by Gilbert C FAURE
January 21, 2015 1:38 PM
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Probiotic, peanut OIT may benefit children with peanut allergies - Healio

Probiotic, peanut OIT may benefit children with peanut allergies - Healio | Allergy (and clinical immunology) | Scoop.it
Allergy Immunology | The administration of a probiotic with peanut oral immunotherapy increased sustained unresponsiveness in children with peanut allergy, according to recent study results.The researchers conducted a double blind,...
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Scooped by Gilbert C FAURE
December 22, 2014 3:51 AM
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Firm develops patch to stops reactions in peanut allergy sufferers - Daily Mail

Firm develops patch to stops reactions in peanut allergy sufferers - Daily Mail | Allergy (and clinical immunology) | Scoop.it
French biotech firm DBV Technologies has created a patch which administers small amounts of the peanut allergen to the skin, so over time the immune system becomes used to it.
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Scooped by Gilbert C FAURE
November 20, 2014 9:41 AM
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Peanut in household dust linked to peanut allergy in children with eczema ... - Medical Xpress

Peanut in household dust linked to peanut allergy in children with eczema ... - Medical Xpress | Allergy (and clinical immunology) | Scoop.it
A new study led by researchers at King's College London in collaboration with the US Consortium of Food Allergy Research and the University of Dundee has found a strong link between environmental exposure to peanut protein during infancy (measured...
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