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Influenza Season Approaching 

Influenza Season Approaching  | Virology News | Scoop.it
The influenza season in South Africa occurs in the winter months and is expected to start in the coming weeks. On average the season begins in the first week of June. However, in past years; the season has started as early as the last week of April and as late as the first week of July. A severe influenza season was experienced in the United States of America and Europe in the winter of 2017-2018. A severe season elsewhere in the world does not mean that South Africa will necessarily experience a severe season in 2018. The severity of a season is due to a combination of factors including the circulating influenza strains, previous immunity in the population and spectrum of underlying illnesses and age distribution of the population. The NICD monitors the progression and severity of the influenza season through its surveillance sites throughout the country to provide real time information on season progression. Annual influenza epidemics result in an estimated three to five million cases of severe illness, and about 290 000-650 000 deaths globally. In South Africa, influenza (commonly known as flu) kills between 6000-11,000 people every year. About half of these deaths are in the elderly, and about 30% in HIV-infected people. The highest rates of hospitalization are in the elderly (65 years and older), HIV-infected people and children less than 5 years old. Pregnant women are also at increased risk of hospitalization and death from flu infections. People with chronic illnesses like diabetes, lung disease, tuberculosis and heart disease are also at increased risk of being hospitalized from the flu. During the flu season in South Africa about 8-10% of patients hospitalized for pneumonia and 25% of patients with flu-like illness (fever and cough) will test positive for influenza. Vaccination is the most effective strategy to prevent influenza. Getting the flu vaccine can reduce flu illnesses, visits to the clinics or to doctors rooms, missed work and school due to flu, as well as prevent flu-related hospitalizations. Vaccinating people with higher risk of severe flu directly protects them from flu infections. Vaccinating pregnant women has been shown to provide protection to both mother and baby during the flu season. HIV-infected adults without severely weakened immune systems also respond well to the vaccine. Vaccination is also recommended for individuals aged >=65 years and individuals with chronic illnesses like diabetes, lung disease, tuberculosis and heart disease. Influenza vaccine for the 2018 season is currently available at public health facilities and at pharmacies. Since it takes about two weeks after vaccination for protective antibodies to develop, it is recommended that people get vaccinated as soon as possible to ensure that they are protected before influenza season starts. The best time to get the flu vaccine is before the season starts (March-June) but getting it later will protect individuals during the rest of the season. Because influenza viruses are constantly changing and immunity from vaccine lasts for about a year, it is necessary to get vaccinated each year before the influenza season. The influenza vaccine that is licensed for use in South Africa covers three of the common influenza strains (influenza A(H3N2), influenza B and influenza A(H1N1)pdm 09). Based on the information on the influenza strains that were circulating during the 2017 Southern Hemisphere influenza season, the 2018 vaccine for the Southern Hemisphere has been changed (changes in influenza B and influenza A(H3N2) component of the vaccine). This means that the vaccine for the 2018 in South Africa will be different from the one which was used in the Northern Hemisphere for 2017/2018 season and the Southern Hemisphere 2017 influenza season. It is also essential to practice good hygiene by properly and frequently washing hands and protecting coughs and sneezes (coughing or sneezing into a tissue or an elbow) to help prevent the spread of seasonal influenza. People who have flu-like symptoms should stay at home to avoid infecting others. Detailed recommendations on target groups, dosages and contraindications for the 2018 can be accessed at http://www.nicd.ac.za/wp-content/uploads/2017/03/Influenza-guidelines-final_24_05_2017.pdf
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
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January 19, 2023 6:04 AM
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Cann's Principles of Molecular Virology - 7th Edition

Cann's Principles of Molecular Virology - 7th Edition | Virology News | Scoop.it

Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!


"Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work.


Instructor review copies: click on this link.

https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo

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March 24, 8:33 AM
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Ancient 'syphilis-like' disease in Vietnam challenges long-held assumptions on congenital infection

The findings of a new study by a Charles Sturt University researcher and colleagues challenge a long-standing assumption used by scientists studying ancient disease. The study is published in the International Journal of Osteoarchaeology.
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March 24, 8:32 AM
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Wildflower folk remedy shows modern potential for tackling antibiotic resistance

Scientists have proven that a wildflower steeped in folklore for its medicinal powers has genuine healing qualities—and the potential to help combat antibiotic resistance. Tormentil, a yellow wildflower found in heath and boglands in the UK, Ireland and across Europe, can inhibit the growth of one of the world's most deadly pathogens.
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March 24, 8:31 AM
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Single-cell sequencing reveals unexpected protist diversity

Researchers from the Earlham Institute, in collaboration with the Department of Biology at the University of Oxford, have discovered three previously unrecognized lineages of the protist Bodo, each with its own bacterial endosymbiont (a symbiotic organism living within the body of its host).
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March 24, 8:30 AM
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Nanoparticles enable large-scale production of advanced cell therapies

Researchers from Xi'an Jiaotong-Liverpool University (XJTLU) in China have developed a streamlined process that makes it easier to produce tiny therapeutic particles released by cells, called exosomes, which are being explored as a new type of medical treatment. Using a nanoparticle-based system, the researchers were able to overcome a major barrier that has slowed the medical and industrial deployment of these therapies. Their findings were published in the journal Advanced Science.
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March 24, 8:29 AM
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Stolen chloroplasts maintained by host-made proteins offer clues to plant cell origins

Every plant cell is the product of a biological merger billions of years ago. Chloroplasts are key structures in plants and algae that capture sunlight, but originally they were free-living bacteria that took up residence inside another cell. Over time, these partners became more closely integrated by sharing genes, proteins, and roles.
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March 10, 5:59 AM
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The coldest 'stars' in the galaxy might actually be alien megastructures

Ever since physicist Freeman Dyson first proposed the concept in 1960, the "Dyson sphere" has been the holy grail of techno-signature hunters. A highly advanced civilization could build a "sphere" (or, in our more modern understanding, a "swarm" of smaller components) around their host star to harvest its entire energy output. We know, in theory at least, that such a swarm could exist—but what would it actually look like if we were able to observe one? A new paper, available on the arXiv pre-print server and soon to be published in Universe from Amirnezam Amiri of the University of Arkansas, digs into that question—and in the process discloses the types of stars that are the most likely to find them around.
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March 10, 5:58 AM
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How a protein pair ensures that faulty mRNA is destroyed

Nonsense-mediated mRNA decay (NMD) is one of the most important processes in our cells to ensure that no faulty or incomplete proteins are produced. Scientists have now identified a central mechanism behind this control system.
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March 10, 5:57 AM
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Amphotericin B promotes respiratory viral entry by enhancing late endosomal maturation and fusion via glucocerebrosidase-mediated ceramide remodeling | Nature Communications

This study reveals that Amphotericin B activates glucocerebrosidase to remodel late endosomal lipid and protein composition, promoting respiratory viral entry. This highlights a risk of secondary viral infections during antifungal therapy.
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March 10, 5:56 AM
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An interstellar comet packed with alcohol? What ALMA found in 3I/ATLAS

Comet 3I/ATLAS continues to make astonishing headlines, thanks to new findings from astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA). This new research reveals that 3I/ATLAS is packed with an unusually large amount of the organic molecule methanol—more than almost all known comets in our own solar system.
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March 10, 5:55 AM
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Nearby red dwarf star hosts at least four planets—with one in the habitable zone

In 2020, a study confirmed that two planets orbited the nearby red dwarf, GJ 887. Now, astronomers have confirmed the existence of two additional planets orbiting GJ 887 in a new study published in Astronomy and Astrophysics. The new study suggests that one of these newly confirmed planets is in the habitable zone.
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March 10, 5:55 AM
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Scientists trace crop viruses back to the last Ice Age

Long before humans cultivated crops or sailed between continents, a group of plant viruses was already evolving among wild plants in Eurasia. According to a new international study published in Plant Disease, the ancestors of modern tymoviruses likely emerged before the last Ice Age, reshaping scientists' understanding of the vast evolutionary history of plant disease.
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March 10, 5:54 AM
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Deep ocean microbes may already be prepared to tackle climate change

Deep-sea waters are warming due to heat waves and climate change, and it could spell trouble for the oceans' delicate chemical and biological balance. However, a study published in Proceedings of the National Academy of Sciences demonstrates that the microbe Nitrosopumilus maritimus may already be adapting well to warmer, nutrient-poor waters. Researchers predict that these surprisingly adaptable iron-dependent ammonia-oxidizing archaea will play an important role in reshaping ocean-nutrient distribution in a changing climate.
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March 24, 8:34 AM
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Multifunctional ACE2-nanobody fusion design for pan-specific neutralization and cardiovascular protection in SARS coronavirus infection

Severe acute respiratory syndrome coronaviruses use the ACE2 receptor for viral entry while downregulating its activity, potentially leading to hypertension and major organ injuries.Dual-action technologies based on soluble ACE2 aimed to neutralize the virus while restoring ACE2's normal enzymatic...
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March 24, 8:33 AM
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Discovery of genetic switch could help turn rice into a perennial crop

Rice is a vital crop that feeds more than half of the world's population. In the wild, many rice species are perennials that live for several years, but the varieties we eat today are typically annuals that must be replanted every season. That is an expensive process for farmers requiring continual labor, seeds and field preparation to keep up with demand. But a cheaper solution may be on the way one day.
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March 24, 8:32 AM
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Genome-hopping 'Starships' may explain why some pest-killing fungi stop working

A new study from Kiel University shows how the massive exchange of mobile genetic elements between fungi can impair their effectiveness against insects and ticks. Microbial fungi, such as the genus Metarhizium, are often used in biological pest control. These fungi attack harmful insects and ticks, thus representing an ecological alternative to chemical agents. However, how effective these fungi remain is determined by an evolutionary arms race between the fungus and its host.
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March 24, 8:31 AM
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Study details neuropsychiatric symptoms and biological mechanisms of long COVID

Nearly three years since the SARS-CoV-2 pandemic was declared over, conservative estimates suggest that between 80 million and 400 million people worldwide have long COVID. This chronic condition associated with the infection is linked to more than 200 symptoms, including fatigue and shortness of breath, as well as neuropsychiatric issues ranging from cognitive dysfunction and sleep disorders to depression and memory loss. These issues impact quality of life and hinder the performance of daily tasks and work.
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March 24, 8:29 AM
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Covid-19 immunity likely to lower risk of another SARS pandemic – study

Covid-19 immunity likely to lower risk of another SARS pandemic – study | Virology News | Scoop.it
Researchers also found existing Covid-19 vaccines could help slow or stop the spread of a new coronavirus.
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March 24, 8:29 AM
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No link between Covid-19 vaccines and sudden cardiac death

No link between Covid-19 vaccines and sudden cardiac death | Virology News | Scoop.it
The study reveals COVID-19 vaccines do not increase sudden cardiac death risk in youth, highlighting the importance of accurate health messaging.
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March 10, 5:58 AM
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DART images reveal asteroids can toss slow 'cosmic snowballs' between moons

About 15% of asteroids near Earth have small moons orbiting them, making binary asteroid systems common in our cosmic neighborhood.
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March 10, 5:57 AM
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Infection-acquired protection against SARS-CoV-2 infection and clinical severity by number of prior infections | Nature Communications

Prior infection is protective against SARS-CoV-2 infection, but the degree of protection provided by multiple subsequent infections is not clear. Here, the authors use data from a household transmission study in Nicaragua and show that 1, 2 or 3+ infections are associated with increasing...
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March 10, 5:57 AM
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Preparation of targeted lipid nanoparticles for precision nucleic acid delivery | Nature Protocols

Preparation of targeted lipid nanoparticles for precision nucleic acid delivery | Nature Protocols | Virology News | Scoop.it
This protocol outlines the steps to prepare functionalized lipid nanoparticles covalently conjugated with whole antibodies or antibody fragments for targeted nucleic acid delivery to different tissues or cell types.
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March 10, 5:56 AM
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Pathogenic virus infects and structurally reorganizes human cells, finds new study

Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat. Researchers from the Medical Faculty of the University of Duisburg-Essen and the University Hospital Essen, Germany, have gained new insights into how these viruses alter the internal structure of their host cells. Their findings are published in the Journal of General Virology.
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March 10, 5:55 AM
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Microbes hitchhiking on marine snow could limit how deep carbon sinks

In some parts of the deep ocean, it can look like it's snowing. This "marine snow" is the dust and detritus that organisms slough off as they die and decompose. Marine snow can fall several kilometers to the deepest parts of the ocean, where the particles are buried in the seafloor for millennia.
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March 10, 5:55 AM
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Infection-Acquired Immunity: Impact of Prior COVID-19 Cases

Infection-Acquired Immunity: Impact of Prior COVID-19 Cases | Virology News | Scoop.it
In a groundbreaking advancement that could reshape our understanding of immunity within the COVID-19 pandemic, a recent study published in Nature Communications reveals compelling insights into how protection against SARS-CoV-2 infection—and the severity of ensuing illness—varies significantly depending...
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March 10, 5:54 AM
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CRISPR-based technique unlocks healing power of mitochondria for heart failure therapy

After a heart attack, the heart struggles to recoup and maintain energy. One-third of patients develop heart failure as a result—a condition that impacts 6.8 million Americans and carries a high lifetime risk, with 1 in 4 adults in the U.S. expected to develop the condition during their lifetime. This makes finding lasting treatment a medical priority.
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