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February 11, 2012 7:15 AM
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Smallpox Through Time

Smallpox Through Time | Virology News | Scoop.it

In 1910, egyptologists discovered smallpox scars on the face of the mummy of Ramses V - the earliest evidence of smallpox in human history. Andrew explains the origins of the disease, and traces its spread into the modern era.

 

EXCELLENT series of short films on smallpox through the ages, courtesy of the Wellcome Trust - and AJ Cann, who tweeted it.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
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January 19, 2023 6:04 AM
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Cann's Principles of Molecular Virology - 7th Edition

Cann's Principles of Molecular Virology - 7th Edition | Virology News | Scoop.it

Cann's Principles of Molecular Virology, - 7th Edition, revised by EP Rybicki. Print Book. ISBN 9780128227848. Now published!!


Instructor review copies: click on this link.

https://protect-za.mimecast.com/s/qU2qCNxKq0i0ZNRQxcmeDdo

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Scooped by Ed Rybicki
January 21, 8:49 AM
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A Study on the Induction of Multi-Type Immune Responses in Mice via an mRNA Vaccine Based on Hemagglutinin and Neuraminidase Antigen

A Study on the Induction of Multi-Type Immune Responses in Mice via an mRNA Vaccine Based on Hemagglutinin and Neuraminidase Antigen | Virology News | Scoop.it
Background: The Influenza A virus (IAV), a pathogen affecting the respiratory system, represents a major risk to public health worldwide. Immunization remains the foremost strategy to control the transmission of IAV.
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January 21, 8:42 AM
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Scientists uncover structure of critical component in deadly Nipah virus

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.
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January 21, 8:41 AM
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RNA's biophysical behavior offers new insights into X chromosome inactivation

Science has revealed some of the secrets of the X chromosome, but many remain. In humans, female cells contain two X chromosomes (XX) and male cells contain one (XY). In each female cell, one X chromosome must be inactivated—crumpled up in such a way that the genetic code it contains cannot be read out.
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January 15, 6:23 AM
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COVID-19 vaccine developed by Brazilian researchers shows promise in mice

COVID-19 vaccine developed by Brazilian researchers shows promise in mice | Virology News | Scoop.it
Studies conducted in mice have shown that the COVID-19 vaccine being developed by researchers at the University of São Paulo's Medical School (FM-USP) in Brazil is safe and efficacious.
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January 15, 6:22 AM
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New mechanism for maintaining genome stability discovered

Genetically speaking, it's a bacterium's worst-case scenario: During transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While these structures have some important roles to play in a cell, R-loops in the wrong place at the wrong time can be disastrous, leading to DNA breaks, mutations, and cell death.
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January 15, 6:21 AM
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Bird flu kills 20 million chickens in US, driving egg prices sky-high

A deadly bird flu outbreak has wreaked havoc on U.S. chicken farms, claiming the lives of over 20 million egg-laying chickens last quarter, marking the worst impact on America's egg supply since the outbreak began in 2022.
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January 15, 6:20 AM
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The bacterium that transformed DNA sequencing

DNA sequencing was revolutionized after scientists discovered a new bacterium in the hot springs of Yellowstone National Park, and today it's a common research technique.
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January 14, 4:14 AM
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Wrong place, wrong time: Why Zika virus hijacks a protein needed for brain growth

The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results in a smaller-than-expected head.
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January 14, 4:12 AM
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Germany races to contain foot-and-mouth outbreak amid export fears

Germany took further steps Monday to limit the potential spread of foot-and-mouth disease, as an outbreak of the virus threatened to hit the country's agricultural exports.
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January 14, 4:09 AM
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Importance of RNA modifications in fungal infection resistance could lead to better treatments

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a German-Austrian research team led by the Leibniz Institute for Natural Product Research and Infection Biology–Hans Knöll Institute (Leibniz-HKI). Their study, published in Nucleic Acids Research, focused on the mold fungus Aspergillus fumigatus, which can cause life-threatening infections, especially in immunocompromised people.
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January 14, 4:08 AM
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Pathology of Red Blood Cells in Patients with SARS-CoV-2

Pathology of Red Blood Cells in Patients with SARS-CoV-2 | Virology News | Scoop.it
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with various hematological disorders. Understanding the pathology of erythrocytes (red blood cells) in coronavirus infection may provide insights into disease severity and progression.
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January 13, 6:34 AM
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Germany reports foot-and-mouth disease in water buffalo

Germany on Friday registered three cases of foot-and-mouth disease in water buffalo on a farm near Berlin, the country's first reported cases of the livestock disease since 1988.
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January 21, 8:50 AM
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Nicking Activity of M13 Bacteriophage Protein 2

Nicking Activity of M13 Bacteriophage Protein 2 | Virology News | Scoop.it
Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication.
Ed Rybicki's insight:
Turns out that either M13 Rep recognises geminivirus Ori sequences, or the geminivirus Rep recognises M13 - because a geminivirus genomes cloned into M13 can be liberated as a replicon in E coli!
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January 21, 8:43 AM
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A wave of cat deaths from bird flu prompts new rules on pet food production

As experts continue monitoring and surveying the environment and the nation's food supply for H5N1 bird flu, a rash of dead cats has many officials on edge.
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January 21, 8:42 AM
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Ancient viral DNA shapes early embryo development, study finds

Over half of our genomes consist of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the genome, researchers at Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have now revealed their crucial role in early embryo development. The study is published in the journal Cell.
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January 21, 8:40 AM
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Associations of infection burden with Kawasaki disease in a population-based setting during 30 years | RMD Open

WHAT IS ALREADY KNOWN ON THIS TOPIC
Kawasaki disease is an acute paediatric vasculitis of unknown origin. Environmental exposures have been suggested to contribute to disease development, but these remain to be defined.WHAT THIS STUDY ADDSThe findings suggest that infections are closely linked with Kawasaki disease, with a wider temporal association than previously described.Further, the data imply that many different agents may induce Kawasaki disease.
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January 15, 6:23 AM
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The mystery of why Covid-19 seems to be becoming milder

The mystery of why Covid-19 seems to be becoming milder | Virology News | Scoop.it
Covid-19 is now ubiquitous – but hospitalisations seem to be on a downward trajectory. No one knows why.
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January 15, 6:22 AM
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Does Hand Sanitizer Kill Norovirus? 3 Ways to Neutralize the Virus

Does Hand Sanitizer Kill Norovirus? 3 Ways to Neutralize the Virus | Virology News | Scoop.it
Infectious disease doctors explain if hand sanitizer kills norovirus, and effective ways to neutralize the stomach bug’s germs, including on surfaces.
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January 15, 6:21 AM
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Genetic mutation linked to higher SARS-CoV-2 risk

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus's ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.
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January 15, 6:09 AM
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Plant-Based Antigen Production Strategy for SARS-CoV-2 Nucleoprotein and RBD and Its Application for Detection of Antibody Responses in COVID-19 Patients

Plant-Based Antigen Production Strategy for SARS-CoV-2 Nucleoprotein and RBD and Its Application for Detection of Antibody Responses in COVID-19 Patients | Virology News | Scoop.it
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, the development of efficient serological tests for monitoring the dynamics of the disease as well as the immune response after illness or vaccination was critical.
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January 14, 4:13 AM
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Scientists engineer nanostructured surfaces hostile to bacteria but friendly to cells

Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells. They found that anodic porous alumina (APA) surfaces prepared using electrochemistry in concentrated sulfuric acid had unprecedented resistance to bacterial growth, but did not hamper cell cultures.
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January 14, 4:10 AM
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Breakthrough Discovery: Unveiling the Pathway of Semliki Forest Virus Entry

Breakthrough Discovery: Unveiling the Pathway of Semliki Forest Virus Entry | Virology News | Scoop.it
In a groundbreaking study conducted by researchers at Uppsala University, crucial insights have been gained regarding the mechanisms by which the Semliki Forest virus infiltrates the central nervous system.
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January 14, 4:08 AM
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Impact of COVID-19 on Utilization of Healthcare Services Among People Living with HIV (PLHIV): A Systematic Review

Impact of COVID-19 on Utilization of Healthcare Services Among People Living with HIV (PLHIV): A Systematic Review | Virology News | Scoop.it
Background and Objectives: People living with HIV/AIDS have been impacted notably by the COVID-19 pandemic in diverse dimensions. Although some impacts of COVID-19 on PLHIV have been well documented, there is still insufficient research that captures the overall understanding of the implications...
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January 14, 4:08 AM
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COVID-19 infection linked to increased cases of ME/CFS

COVID-19 infection linked to increased cases of ME/CFS | Virology News | Scoop.it
New findings from the National Institutes of Health's (NIH) Researching COVID to Enhance Recovery (RECOVER) Initiative suggest that infection with SARS-CoV-2, the virus that causes COVID-19, may be associated with an increase in the number of myalgic encephalomyelitis/chronic fatigue syndrome...
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January 13, 6:32 AM
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First Detection of Alphacoronavirus in Bats from the World’s Largest Wetland, the Pantanal, Brazil

First Detection of Alphacoronavirus in Bats from the World’s Largest Wetland, the Pantanal, Brazil | Virology News | Scoop.it
Coronaviruses (CoV) infect a wide variety of hosts, causing epidemics in humans, birds, and mammals over the years. Bats (order Chiroptera) are one of the natural hosts of the Coronaviridae family. They represent 40% of the total number of mammal species in the Pantanal, a biodiversity hotspot in...
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