As the global information economy intensifies, voices from the global South have been calling for more coordinated and deliberate work to defend what is known as the global “knowledge commons.” Movements resisting international trade agreements and the patenting of “intellectual property” have been inspired and guided by activists in places like Brazil, India, and South Africa, where strong resistance to TRIPS--or trade-related intellectual property rights agreement--helped keep life-saving medications more affordable and challenged the commodification of knowledge.