Telomeres protect the ends of chromosomes from damage. This image shows telomeres (green) and DNA (blue) during DNA repair activities.Click here for a high-resolution image.Credit: Salk Institute LA JOLLA—As we age, the end caps of our chromosomes, called telomeres, gradually shorten. Now, Salk scientists have discovered that when telomeres become very short, they communicate with mitochondria, the cell’s powerhouses. This communication triggers a complex set of signaling pathways and initiates an inflammatory response that destroys cells that could otherwise become cancerous.
To understand and combat rapid aging, we need to understand what causes aging, chronic diseases, and decline. We call these things the hallmarks of aging—the underlying common pathways or mechanisms of aging. Each hallmark is influenced by the others and affected by various imbalances—too much or too little of certain inputs that can negatively impact the expression and progression of the hallmark. Understanding those interactions and weblike connections is the key to solving the puzzle of aging.
In today’s episode of my series I’m calling Health Bites, I dive into the 10 distinct hallmarks of aging and how to address them. What I’ve discovered has blown my mind and changed the way I approach my own health and the health of my patients. I’ve compiled it all into a new book called Young Forever, which comes out on February 21, 2023. Learn more and preorder the book at youngforeverbook.com.
This episode is brought to you by Rupa Health and Athletic Greens.
Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at https://RupaHealth.com.
AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now when you purchase AG1 from Athletic Greens, you will receive 10 FREE travel packs with your first purchase by visiting https://athleticgreens.com/hyman.
A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and […]
A randomized controlled trial has found that caloric restriction slows aging in adults. The study, led by researchers from the Butler Columbia Aging Center at the Columbia University Mailman School of Public Health, is published in Nature Aging.
Young blood has a rejuvenating effect when infused into older bodies, according to recent research: Aging hearts beat stronger, muscles become stronger,...
Experts encourage stimulating mitochondria to enhance longevity. A leading biohacker, Molly Maloof, M.D., shares some underrated methods to do just that.
Diminished grip strength has proven to be a surprisingly reliable indicator of health issues like cardiovascular events, declining brain function and metabolic disease. And that’s not all a weak grip can point to. Turns out grip strength may be related to how fast or slow our bodies are aging…
The artificial intelligence program scored between 52.4 and 75 percent across the three-part US Medical Licensing Exam (USMLE). Each year's passing threshold is around 60 percent.
Blueprint is a public science experiment to determine whether it’s possible to stay the same biological age. This requires slowing down aging processes as much as possible and then reversing the aging that has happened. Currently my speed of aging is .76 (DunedinPACE). That means for every 365 days each year, I age 277 days. My goal is to remain the same age biologically for every 365 days that pass.
I
Original Image in Thumbnail: Credit to Dustin Giallanza
In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic […]
With vitamin D's vast health benefits, it's exceedingly clear that achieving vitamin D sufficiency is key for whole-body health throughout the lifespan.*
CEO Chris Mirabile, Founder & CEO of NOVOS, is a serial entrepreneur and longevity expert, hosted a webinar focusing on all things longevity technology to slow down your aging. Chris goes over applications and devices that can help you be younger for longer.
Dan Buettner, an expert in Blue Zones and New York Times bestselling author, explains that the best exercise to support longevity is no other than walking.
Erythrocytes transport oxygen through the body to cells and return carbon dioxide back to the lungs for removal from the body. Red blood cell counts can reflect deficits in many different body systems. The presence of red blood cells decreases with age, and the quality and quantity of red blood cells can be indicative of systemic failures associated with multiple aging processes. This may account for why red blood cell counts are so good at predicting biological age.
To get content containing either thought or leadership enter:
To get content containing both thought and leadership enter:
To get content containing the expression thought leadership enter:
You can enter several keywords and you can refine them whenever you want. Our suggestion engine uses more signals but entering a few keywords here will rapidly give you great content to curate.