In a groundbreaking editorial published on May 29, 2025, in the esteemed journal Aging (Volume 17, Issue 5), Editor-in-Chief Marco Demaria, affiliated with the European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), and the University of Groningen...
Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.
A recent study led by UC San Diego reveals that metformin, a first-line treatment for type 2 diabetes, may help women with diabetes live longer, reducing the risk of death by 30%. The research, using a target trial emulation framework, suggests that metformin could contribute to exceptional longevity by activating longevity-related genes like FOXO3. Learn more about how metformin may extend lifespan and its role in aging and disease prevention.
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