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El grupo francés de análisis clínicos Labco ha tomado el 100% del Centro Inmunológico de Cataluña (CIC), en el que tenía una participación mayoritaria desde 2011, y ubicará en sus instalaciones de El Prat de Llobregat (Barcelona) la sede mundial de Labco Nôus, su nueva marca de analítica especial y pruebas de alto valor diagnóstico.. Noticias, última hora, vídeos y fotos de Genética en lainformacion.com 
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Article first published online: 20 DEC 2013 DOI: 10.1002/cyto.a.22429 © 2013 International Society for Advancement of Cytometry
Alfredo Corell's insight:
This issue of Cytometry contains three reviews that further celebrate the longstanding, intense, and happy marriage between Cytometry and Immunology, as highlighted recently during the XV International Congress of Immunology, held in Milan, Italy, August 22–27, 2013. Scanning the scientific contributions of the Conference reveals that cytometric technology was used in the vast majority of abstracts and presentations. In other words, very few scientists did not switch on one or more lasers! It is obvious, that nowadays very few studies in the field of Immunology are possible without techniques based upon single cell analysis.
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Alfredo Corell's insight:
Cytometry Part B: Clinical Cytometry - Volume 84, Issue 5 Pages 279–357 Issue edited by: Marie C. Béné, Gerald E. Marti
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A credit card-sized chip can diagnose HIV infection and provide T cell counts to guide treatment, according to a recent paper in Science Translational Medicine.
Alfredo Corell's insight:
The chip is designed to work in a battery-powered handheld device that would “deliver simple HIV diagnostics to patients anywhere in the world, regardless of geography or socioeconomic status,” the researchers say in the paper. Direct Link to the journal:
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Liver Disease Diagnostics: Antibody-Based Diagnosis of Autoimmune Liver Disease For the launch of our Liver-9-Line immunoblot test (to our press release “Liver Disease Diagnostics by Immunoblot” of May 16, 2011), I dug through a pile of literature...
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The diagnosis of food allergy: a systematic review and meta-analysis. Full text. http://t.co/PrRzTekHct
Alfredo Corell's insight:
The diagnosis of food allergy: a systematic review and meta-analysis K. Soares-Weiser1, Y. Takwoingi2, S. S. Panesar3, A. Muraro4, T. Werfel5, K. Hoffmann-Sommergruber6, G. Roberts7,8,9, S. Halken10, L. Poulsen11, R. van Ree12,13, B. J. Vlieg-Boerstra14, A. Sheikh3,15,*, on behalf of the EAACI Food Allergy and Anaphylaxis Guidelines Group†
Conclusions The evidence base is limited and weak and is therefore difficult to interpret. Overall, SPT and sIgE appear sensitive although not specific for diagnosing IgE-mediated food allergy.
Gilbert C FAURE's curator insight,
December 15, 2013 11:16 AM
Metaanalysis of heterogeneous biomarkers and more heterogeneous clinical situations is not the best way to synthetise a complex medical syndrome
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An article on reducing errors in analytical laboratory testing with the help of EQA/PT programmes (Reducing errors in laboratory testing with the help of EQA and Proficiency Testing programmes
Alfredo Corell's insight:
All Your Immunology Proficiency Programs for 2014 at GECLID-SEI and GECLID-SEI-SIC:
web: http://www.geclidsei.uva.es/ ; 2014 listing and prizes: http://www.geclidsei.uva.es/mod/resource/view.php?id=2008 2014 inscription bulletin: http://www.geclidsei.uva.es/mod/feedback/view.php?id=3203
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BOLETIN N° 15 - TIDECA - TIEMPO DE CAMBIOS EN LA BIOQUÍMICA Y EN LA SALUD
Alfredo Corell's insight:
Los profesionales que en sus laboratorios no poseen la temperatura regulada y constante a lo largo del año, especialmente los que realizan técnicas semiautomáticas o manuales, como EIA, ELISA, RIA, IRMA, IFI, IFA, etcétera, incluidas las técnicas de química clínica o enzimáticas, podrán observar variaciones pero, esas variaciones pueden ocurrir también a causa del pH y la fuerza iónica de los buffers y las soluciones de lavado que, a su vez, sus valores varían con los cambios de la temperatura y afectan las condiciones del equilibrio. En muchas ocasiones, distintos fabricantes optimizan sus ensayos con soluciones reguladoras, de ensayo o de lavado con pH y FI apropiadas para sus ensayos particulares y seguramente no coinciden con los de otros analitos ni entre fabricantes.
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By Anna Azvolinsky, LiveScience Contributor Published: 12/04/2013 03:25 PM EST on LiveScience A sensitive new DNA test can predict how long ovarian cancer patients will survive, and guide personalized treatment decisions, according to new research.
Alfredo Corell's insight:
The technology, called QuanTILfy, counts the number of cells called tumor-infiltrating lymphocytes (TILs) in a cancer patient's tumor biopsy. Cancer patientswith more of these cells in their tumor tend to have better outcomes, previous studies in ovarian, colorectal and other cancers have shown. A divulgative new in spanish: http://www.elmundo.es/salud/2013/12/09/52a0d4010ab740f5568b458f.html ;
The original publication Sci Transl Med 4 December 2013:
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It's time to celebrate...well, you! It's World Quality Month!
Alfredo Corell's insight:
November is World Quality Month
that's also for Immunology Laboratory diagnosis
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Background Celiac disease (CD) is a chronic disorder in genetically predisposed individuals in which damage to the small intestine is caused by eating foods containing gluten. The prevalence has b ...
Alfredo Corell's insight:
Author:Nordyke, Katrina (Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health)Title:Mass screening for celiac disease: a public health intervention from the participant perspectiveDepartment:Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health
Conclusions Our findings suggest that it is possible for participants to avoid excess anxiety during CD screening. However, there was not consensus among participants that being detected and treated had improved their health-related quality of life or that the immediate benefits outweighed the harm caused by being detected in this way. When considering mass screening, the affect on the participants is important to take into account and our findings shed light on some of the potential impacts a CD mass screening could have on participants.
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Alfredo Corell's insight:
Excepcional herramienta por colaboración entre el Hospital Clinic de Barcelona y la UPC: procesamiento digital de imágenes obtenidas al microscopio.
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No time for Quality? Reasons to Reevaluate and Reinvest in a Lab Quality Program : September-October 2013 - MLM Magazine - Peer-to-Peer Information Source for Clinical Lab Management
Alfredo Corell's insight:
Poor quality in the lab not only forces an organization into a reactive mode of problem solving, but it also creates a higher cost burden than a laboratory with an effective quality infrastructure experiences. Reruns performed due to quality control failures can significantly increase testing costs and cut into a lab’s bottom line. Furthermore, according to a recent study, correction of errors across all phases of laboratory testing can consume 12-35 percent of technician time.
Gilbert C FAURE's curator insight,
October 28, 2013 10:07 AM
quality is a state of mind, andshould not be an administrative coercition |
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provides a basic understanding of the principles of laboratory tests in the context of screening and diagnostic approaches, as well as antimicrobial susceptibility testing
Alfredo Corell's insight:
Download here the complete pdf: http://apps.who.int/iris/bitstream/10665/85343/1/9789241505840_eng.pdf
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TREC Towards Health. PerkinElmer is proud to introduce the first commercial TREC screening assay. The assay forms a part of a complete system, CE-marked to a...
Alfredo Corell's insight:
TREC assay to diagnosis SCID (first CE-marked diagnostic kit)
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La variedad de las especialidades de los profesionales que conforman el IDID permite integrar de manera interdisciplinaria la atención del paciente Nota de prensa.- El Instituto Docente de Inmuno Diagnóstico (IDID) es el primer...
Alfredo Corell's insight:
Nos alegramos de la apertura de un gran centro de diagnóstico inmunológico en Caracas Entre los objetivos del IDID destacan: diagnosticar al paciente portador de enfermedades alérgicas, inmunodeficiencias primarias o secundarias, autoinmunes órgano específicas y del colágeno vascular, entre otras; facilitar la aplicación de tratamientos farmacológicos, emplear nuevos métodos inmuno-moduladores y ofrecer exploraciones inmuno-diagnósticas de respuesta inmunológica mediada por anticuerpos.
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A wiki about light chains and their utility in lab diagnosis
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Boletin de inscripción 2014
Programas, Esquemas y Precios 2014: http://www.geclidsei.uva.es/mod/resource/view.php?id=2008
Alfredo Corell's insight:
GECLID, se consolida como proveedor de calidad para inmunología y citometría. Algunas pruebas sólo se ofertan en GECLID y no en otros programas EPT ni europeos ni en otros continentes: -Actividad hemolítica total del complemento (CH50) -Actividad funcional de linfocitos T en respuesta a mitógenos -Actividad funcional de monocitos y granulacitos (fagocitosis y quimiotaxis)
son entre otros... nuestras ofertas exclusivas. La calidad nuestra seña de identidad.
Inscripción via web en:http://www.geclidsei.uva.es/mod/feedback/view.php?id=3203
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First Molecular Test to Diagnose Eosinophilic Esophagitis Science Daily (press release) The test, based on a 96 gene expression profile, "offers an unprecedented opportunity to improve diagnosis and treatment, and a platform approach for other...
Alfredo Corell's insight:
Gastroenterology
Volume 145, Issue 6 , Pages 1289-1299, December 2013Molecular Diagnosis of Eosinophilic Esophagitis by Gene Expression ProfilingTing Wen, Emily M. Stucke, Tommie M. Grotjan, Katherine A. Kemme, J. Pablo Abonia, Philip E. Putnam, James P. Franciosi, Jose M. Garza,Ajay Kaul, Eileen C. King, Margaret H. Collins, Jonathan P. Kushner, Marc E. Rothenberg Scientific publication in:
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Each food fish can cause specific allergies
Alfredo Corell's insight:
Go to the journal article:
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XXI REUNION DE LA SOCIEDAD ANDALUZA DE ANALISIS CLINICOS
Alfredo Corell's insight:
6-7-8 de Marzo de 2004 Parador de la Arruzafa - Córdoba
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4th Edition reviews “one of the most valuable of its genre and…addressed to a wide audience…. Written in such an attractive way, being both informative and stimulating” (Zbigniew Darzynkiewicz, Trends in Cell Biology)
Alfredo Corell's insight:
This reference explains the science and discusses the vast biomedical applications of quantitative analytical cytology using laser-activated detection and cell sorting. Now in its fourth edition, this text has been expanded to provide full coverage of the broad spectrum of applications in molecular biology and biotechnology today. New to this edition are chapters on automated analysis of array technologies, compensation, high-speed sorting, reporter molecules, and multiplex and apoptosis assays, along with fully updated and revised references and a list of suppliers.
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A lot of people strive to make their microbiology laboratory "error free". Whilst this could be said to be an admirable goal, maybe we need to think about what we wish for a little further.. A prog...
Alfredo Corell's insight:
The same applies for an Immunology lab. The post is quite interesting, pointing out crucial aspects of errors at the lab. External Proficiency Testing is just one of the tools for avoiding some error sources
"So maybe the next time your boss comes to you and says “Congratulations, so far this year we have had no errors, and no complaints from laboratory users”, maybe the response should be “So what are we doing wrong?….”
Gilbert C FAURE's curator insight,
November 22, 2013 6:22 AM
think positive on quality management although applications of regulations can be so negatively coercitive...
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When patients in the emergency department (ED) are diagnosed with influenza by means of a rapid test, they get fewer unnecessary antibiotics, are prescribed antiviral medications more frequently, and have fewer additional lab tests compared to...
Alfredo Corell's insight:
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VANCOUVER, BRITISH COLUMBIA, CANADA—In this beautiful port city, a national gathering of clinical laboratory and anatomic pathology experts convened last week and tackled serious issues concerning the accuracy and integrity of the diagnostic test...
Alfredo Corell's insight:
one presentation discussed the source of errors in anatomic pathology. It was delivered by Gregory J. Flynn, M.D., a pathologist who is the Managing Director of the Institute for Quality Management in Healthcare in Toronto, Ontario. He explained how each phase—pre-analytical, analytical, and post-analytical—could be the source of systemic errors that would affect the accuracy of the patient’s diagnosis and negatively impact patient safety.
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