Intrigued by the new hypothesis from Furmanski and Murcia that the 1918 influenza pandemic may have emerged through reassortment in horses—not pigs or birds.
Their paper, published last month in The Journal of Infectious Diseases, argues that wartime equine mobilization created ideal conditions for avian and human viruses to mix. Horses, like pigs, express both α2,3 and α2,6 sialic acid receptors, making them potential “bridge hosts” for influenza evolution.
A fascinating intersection of molecular virology and historical epidemiology—and a reflection of how hard it is to piece together how pandemics begin.
Did you know that we have millions of different antibodies, but each white blood cell in our immune system produces only one kind of antibody?
In 1975 Georges Köhler and Cesar Milstein developed a method to fuse a normal antibody-producing cell with a tumour cell, forming a hybrid that was both immortal and could create a specific antibody. Their hybrid cell could produce antibodies of the same type – monoclonal antibodies – in whatever quantities are needed for research and medicine.
The production of monoclonal antibodies has enabled researchers to improve tests for infectious diseases, design completely new therapeutic strategies for diseases such as cancer, better explain the mechanisms behind autoimmune diseases and suppress rejection in organ transplants among other breakthroughs.
While the market for monoclonal antibodies is now worth billions of dollars, Köhler and Milstein did not patent their technique or benefit financially by forming a company, instead remaining in research.
Köhler shared the 1983 Nobel Prize in Physiology or Medicine with Niels K. Jerne and César Milstein. Learn more about their work: https://bit.ly/3XLsMYX
Image: Anti-Cancer Antibodies. Small chemical ornaments (cones) slow the release of anti-cancer antibodies (blue) from this functionalised mesoporous silica (orange). | 19 commentaires sur LinkedIn
"The refusal or inability of global health to consider the wider picture of international economic and political inequalities suggests that most of its practitioners are content to remain as saviors, even if the cost includes a world organized to produce the victims they purportedly rescue"
Jesse Bump is spot on, more so after the past couple of months
There is almost no doubt that our measles elimination status will be voided by the end of this year. The only question remaining is whether we exceed the number of cases in 1992 (2,126). (I don't bet; but if I did, I would say that we will easily reach this figure, even knowing that we are severely undercounting the current outbreak).
A second child in Texas (8 years old) has died this week. Cases have not yet peaked. Cases continue to crop up in more and more municipalities and regions of the US.
"Measles was declared eliminated from the United States in 2000. This meant the absence of the continuous spread of disease was greater than 12 months. This was thanks to a highly effective vaccination program in the United States, as well as better measles control in the Americas region."
We need real leaders, more than ever. And those that can do the most good appear more concerned with appearing obedient to their patrons than to serving the public.
Learn about the history of immunology in this video. Perfect for CSIR NET, GATE and other competitive exams. Explore key concepts from Kuby Immunology to ace your competitive exams!
History of Immunology/What is the history of Immunology #Immunology #HistoryOfImmunology #Vaccines #EdwardJenner #LouisPasteur #ImmuneSystem #Antibodies #CellularImmunity #HumoralImmunity #Phagocytosis #ClonalSelection #TCells #BCells #Cytokines #MonoclonalAntibodies #mRNAVaccines #Immunotherapy #MedicalHistory
Highly Pathogenic Avian Influenza H5N1: History, Current Situation, and Outlook – An excellent up-to-date review on the history, pathogenicity, evolution, and…
In just five years, SARS-CoV-2 became one of the most closely examined viruses on the planet. Researchers have published about 150,000 research articles and 17…
Robert F. Kennedy Jr.’s efforts to make the use of the MMR vaccine voluntary are not only letting loose measles but also will allow mumps and rubella to return to America.
#microbiology #microorganisms #bs #students Golden age of microbiology, immunological studies in history of microbiology It will be just me reading the book and explaining the difficult terms or concepts and if i don't know i will search midway.. so its basically a study together.. today will include introduction of microbiology, microorganisms and may be some history.. i am completely new to this book.. let's explore together...I want a place for students to study microbiology with fun and not just a burden.. so you can ask me questions related to microbiology, As your senior i will answer it to the best of my abilities...😁😁
Discover the fascinating journey of immunology and the groundbreaking development of vaccines in this video!
We delve into:
The origins of immunology, starting with ancient practices like variolation. The revolutionary work of Edward Jenner and the first smallpox vaccine. Contributions by Louis Pasteur, who expanded vaccine science to diseases like rabies and anthrax. The evolution of immunology as a scientific discipline and its impact on modern medicine. How vaccines have transformed public health and continue to save millions of lives.
Today, after 55 years, my dad, Professor Myron M. (Mike) Levine, retires from the full-time faculty at the University of Maryland School of Medicine. If you… | 29 comments on LinkedIn
The goal of SMI's Oral History Project is to preserve a piece of the knowledge of leaders in the field of mucosal immunology for young investigators emerging in the field today.
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