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![]() Researchers have strived to determine how neurons are produced and integrated into the brain throughout adult life. In an intriguing twist, scientists provide evidence that adult-born neurons are derived from a special type of circulating blood cell produced by the immune system. The findings -- which were made in crayfish -- suggest that the immune system may contribute to the development of the unknown role of certain brain diseases in the development of brain and other tissues.
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![]() By studying the genetic mechanisms that enable regeneration in our distant evolutionary cousins, scientists hope to one day uncover potentially latent healing abilities that may lie hidden in our own genome. Four professors are undertaking the basic scientific research needed to begin to answer these and other questions. Each of them approaches the problem from a different angle, focusing on different aspects of regeneration, and using different vertebrate models.
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![]() PLOS Biology is an open-access, peer-reviewed journal that features works of exceptional significance in all areas of biological science, from molecules to ecosystems, including works at the interface with other disciplines.
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![]() Researchers have used mRNA sequences, rather than DNA, to more efficiently create a reference database that can be used for proteomic analysis of Xenopus frogs. The researchers used their reference database to identify over 11,000 proteins from an unfertilized Xenopus egg and estimate the abundance of these proteins. The method outperformed comparison proteomic analyses based on a preliminary, unpublished Xenopus genome and other protein reference databases.
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![]() ns Novartis and Google are teaming up on a smart contact lens that could help monitor glucose for those with diabetes and adjust focus for those with trouble focusing on objects up close.
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![]() Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. By - Prof Bruno Dubois MD, Prof Howard H Feldman MD, Claudia Jacova PhD, Prof Harald Hampel MD, José Luis Molinue...
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![]() Scientists have created an artificial, network-like cell system that is capable of reproducing the dynamic behavior of protein synthesis. This achievement is not only likely to help gain a deeper understanding of basic biological processes, but it may, in the future, pave the way toward controlling the synthesis of both naturally-occurring and synthetic proteins for a host of uses.
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![]() Investigators have successfully transplanted hearts from genetically engineered piglets into baboons' abdomens and had the hearts survive for more than one year, twice as long as previously reported. This was achieved by using genetically engineered porcine donors and a more focused immunosuppression regimen in the baboon recipients, according to a new study.
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![]() Malaria parasites exploit the function of the epigenetic regulator HP1 to promote survival and transmission between human hosts, a new study shows. Using HP1 the parasite controls expression of surface antigens to escape immune responses in the infected victim. This prolongs survival of the parasite in the human blood stream and secures its transmission via mosquitoes. The study paves important avenues for new intervention strategies to prevent severe disease and malaria transmission.
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![]() A new mouse model has allowed researchers to explore, for the first time, the biological roots of aggressive behavior in females, both toward each other and the pups of others. Their findings provide the basis for developing additional mouse strains that will enable a better understanding of the neural and genetic basis of behavior relating to reproduction in females, and the differences between males and females.
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![]() Regulatory News: ERYTECH Pharma (Paris:ERYP) (Euronext Paris: FR0011471135 - ERYP), the French biopharmaceutical company that develops innovative &lsq
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July 11, 2014 10:38 AM
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A Miss. baby born with HIV and hoped to have been cured by aggressive drugs started right after birth now shows signs of infection. Dr. Anthony Fauci of the NIH says the nearly 4-year-old girl is responding well to renewed treatment. (July 10) Video provided by AP
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July 9, 2014 10:51 AM
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Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.
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Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.
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