Key points. A recombinant antibody recognizing the D1 domain of β2 glycoprotein I induces fetal loss and clot formation in animal models. The CH2-deleted antibody fails to activate complement and prevents the ...
Antiphospholipid syndrome (APS) is an autoimmune disorder with increased risk for thrombosis and pregnancy losses. B2GPI is the major antigen for clinically relevant antibodies in APS. We engineered a molecule, A1-A1, ...
Antiphospholipid Syndrome: Using Anticoagulants Properly Pharmacy Times The autoimmune disorder antiphospholipid syndrome (APS) earns its name from its laboratory profile, but in a complicated way: over time, we've learned that antiphospholipid...
14th International Congress on Antiphospholipid Antibodies & 4th Latin American Congress on Autoimmunity Fecha de Inicio: 18/09/2013 Fecha de Finalización: 21/09/2013 Ciudad: Rio de Janeiro País: Brasil Seleccione la/s especialidad/es a las que...
Statins to Treat an Autoimmune Clotting Disorder Called Antiphospholipid ...Outcome Magazine (blog)11/11/2012 New research suggests that statins, traditionally used for cholesterol lowering, could be used in the management of individuals who are at...
One mechanism by which circulating antiphospholipid/anti-β2GPI antibodies may promote thrombosis is by inducing the release of procoagulant microparticles from endothelial cells. However, there is no information available ...
Rheumatology Medical Article: Top 10 clinical research developments in antiphospholipid syndrome (Top 10 clinical research developments in antiphospholipid syndrome: Current Rheumatology Reports http://t.co/YhLKaxjBBI...
Lupus Foundation of America Grants Lupus Research Fellowships and Career ... MarketWatch (press release) ... Ph.D.Project Title: Role of microRNAs in Trophoblast Responses to Antiphospholipid Antibodies.
Hospital for Special Surgery presents, Top Ten Points Antiphospholipid Antibody-Positive Patients Should Know Before Undergoing a Surgical Procedure (RT @Alliance4Lupus: Top 10 Points Antiphospholipid Anitbody-Positive Patients Should Know Before ...
Rituximab shows promise for clinical problems tied to antiphospholipid antibodiesEurekAlert (press release)Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related...
... suggests that statins, traditionally used for cholesterol lowering, could be used in the management of individuals who are at risk for developing clotting because they have autoimmune antiphospholipid antibodies (aPL).
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