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Automated trading with performance weighted random forests and seasonality Publicati http://t.co/Ltz85DIxjG 
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In this study of autoimmunity among a population of Gullah African Americans in South Carolina, the links between environmental exposures and autoimmunity (presence of antinuclear antibodies (ANA)) have been assessed.
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The antinuclear antibody (ANA) test is widely used as a serological marker of autoimmune disease. Antinuclear antibodies are immunoglobulins or antibodies that bind to one or more antigens expressed within the nucleus of human cells.
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When to order an antinuclear antibody test for the generalist (via @DrAiLynTan) #rheum #meded http://t.co/QbyfnhnF66
Gilbert C FAURE's insight:
a simple test order, but still difficult for clinicians to interpret in diverse clinical contexts
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The American Journal of Medicine, Volume null, Issue null, Pages null, null, Authors:Aryeh M.
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Two types of autoimmune hepatitis have been proposed; type 1 is defined by positive results on testing for antinuclear antibodies and smooth-muscle antibodies, and type 2 by positive results on testing for antibodies against ...
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by Christie Fitch-Rogalsky, Whitney Steber, Michael Mahler, Terri Lupton, Liam Martin, Susan G. Barr, Dianne P. Mosher, James Wick, Marvin J.
Gilbert C FAURE's insight:
This is the first study to evaluate the serological and clinical features of patients referred through a CT system because of a positive ANA. The spectrum of autoantibody specificities was wide with anti-Ro52/TRIM21 being the most common autoantibody detected. Approximately 15% of referrals had only antibodies to DFS70, the vast majority of which did not have clinical evidence for an AARD. These findings provide insight into the utility of autoantibody testing in a CT system.
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Immunofluorescent imaging has been a powerful technique in helping to identify intracellular nuclear and cytoplasmic molecules which are target antigens of autoantibodies in systemic autoimmune disorders.
Gilbert C FAURE's insight:
too bad, not open
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From
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Missed It? Antinuclear antibody staining patterns and clinical features of Systemic Lupus Erythematosus: BMJ: http://t.co/ACD4DoYpwk
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An abstract is unavailable. (Most Popular: Improving the Clinical Utility of Antinuclear Antibody Reporting By Incorporating Likelihood Rat...
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Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease characterized by the production of antinuclear autoantibodies. Antinuclear autoantibody development is recognized as one of the initial stages of ...
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