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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
August 16, 2013 2:38 PM
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Genalyte Launches Type 1 Diabetes Antigen Panel, BDC Collaboration - Genetic Engineering News

Genalyte Launches Type 1 Diabetes Antigen Panel, BDC Collaboration - Genetic Engineering News | AUTOIMMUNITY | Scoop.it
Genalyte Launches Type 1 Diabetes Antigen Panel, BDC Collaboration
Genetic Engineering News
The T1D panel measures autoantibodies to insulin, proinsulin, GAD 65, GAD 67, IA-2 (PTPRN, ICA512), phogrin (PTPRN2, IA-2beta), and ZnT8 (SLC30A8).
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Scooped by Gilbert C FAURE
July 23, 2013 10:07 AM
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JAMA Network | JAMA Pediatrics | Infant Exposures and Development of Type 1 Diabetes Mellitus:  The Diabetes Autoimmunity Study in the Young (DAISY)

JAMA Network | JAMA Pediatrics | Infant Exposures and Development of Type 1 Diabetes Mellitus:  The Diabetes Autoimmunity Study in the Young (DAISY) | AUTOIMMUNITY | Scoop.it
Infant Exposures and Development of Type 1 Diabetes Mellitus:  The Diabetes Autoimmunity Study in the Young (DAISY) http://t.co/BOBJv2GUN5
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Scooped by Gilbert C FAURE
July 14, 2013 3:13 AM
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Patterns of ß-cell Autoantibody Appearance and Genetic ... - Diabetes

In a prospective birth cohort comprising children with HLA-conferred susceptibility to type 1 diabetes (T1D) the pattern of autoantibody appearance was analyzed in 520 children with advanced β-cell autoimmunity associated ...
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Scooped by Gilbert C FAURE
April 12, 2013 9:45 AM
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HLA-A*24 Is an Independent Predictor of 5-Year Progression to Diabetes in Autoantibody-Positive First-Degree Relatives of Type 1 Diabetic Patients

HLA-A*24 IIndependent Predictor of 5-Year Prog 2 Di in Autoantibody-Positive First-Degree Relatives of T1 Patients http://t.co/Ksu1wup0sq
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Scooped by Gilbert C FAURE
March 9, 2013 2:46 AM
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PLOS ONE: The Association between IgG4 Antibodies to Dietary Factors, Islet Autoimmunity and Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young | diabetes and more

PLOS ONE: The Association between IgG4 Antibodies to Dietary Factors, Islet Autoimmunity and Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young | diabetes and more | AUTOIMMUNITY | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
February 14, 2013 12:02 PM
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Humoral responses to islet antigen-2 and zinc transporter 8 are ...

HLA-A*24 genotype and autoantibody responses to insulin (IAA), glutamate decarboxylase (GADA), IA-2, IA-2β and ZnT8 were analysed in samples collected from patients with recent-onset type 1 diabetes. After correction for ...
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Scooped by Gilbert C FAURE
February 9, 2013 1:52 PM
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Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus

Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus | AUTOIMMUNITY | Scoop.it
Endocrinology Medical Article: Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus (Zinc transporter 8 autoantibody (ZnT8A) could help differentiate...
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Scooped by Gilbert C FAURE
February 7, 2013 10:59 AM
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Type 1 diabetes: Cardiff researchers in vaccine trial - BBC News

Type 1 diabetes: Cardiff researchers in vaccine trial - BBC News | AUTOIMMUNITY | Scoop.it
BBC News
Type 1 diabetes: Cardiff researchers in vaccine trial
BBC News
The Cardiff University team is working with King's College London on the trial with type 1 diabetes charity JDRF and the Australian Health and Medical Research Council.
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Scooped by Gilbert C FAURE
January 18, 2013 2:35 PM
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Anti-serpin Antibody-mediated Regulation of Proteases in Autoimmune Diabetes

Anti-serpin Antibodies in Type 1 Diabetes [Immunology] http://t.co/gAQBzH5x #JBCTCB
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Scooped by Gilbert C FAURE
January 2, 2013 11:32 AM
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ScienceDirect.com - Cellular Immunology - Th17 cells in type 1 diabetes

ScienceDirect.com - Cellular Immunology - Th17 cells in type 1 diabetes | AUTOIMMUNITY | Scoop.it
New review article in Cellular Immunology explores the role of Th17 cells in type 1 diabetes http://t.co/7K6PVsqK
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Scooped by Gilbert C FAURE
December 23, 2012 4:41 AM
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Prospective evaluation of risk factors for ... [Pediatr Diabetes. 2012] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 20, 2012 3:54 AM
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Researchers reveal role of dendritic cells in Type 1 diabetes - News-Medical.net

Researchers reveal role of dendritic cells in Type 1 diabetes News-Medical.net The researchers reveal the role of the innate immune cells, especially the dendritic cells, that cause the activation of the killer T-lymphocytes whose action is...
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Scooped by Gilbert C FAURE
December 14, 2012 1:20 PM
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Autoimmune Polyglandular Syndrome Type 3 with Anorexia

Autoimmune Polyglandular Syndrome Type 3 with Anorexia | AUTOIMMUNITY | Scoop.it
GAD autoantibody and ICA were positive, and he was diagnosed with slowly progressive type 1 diabetes mellitus (SPIDDM). Thyroid autoantibodies were positive. According to these findings, he was diagnosed with autoimmune ...
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Scooped by Gilbert C FAURE
August 1, 2013 2:46 AM
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Proinsulin/Insulin Autoantibodies Measured With...

Proinsulin/Insulin Autoantibodies Measured With... | AUTOIMMUNITY | Scoop.it
Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity on diabetes and more curated by Ellen H Ullman, MSW (Proinsulin/Insulin Autoantibodies Measured With...
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Scooped by Gilbert C FAURE
July 15, 2013 5:48 AM
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Elimination of T cell reactivity to pancreatic β cells and partial preservation of β cell activity by peptide blockade of LFA-1:ICAM-1 interaction in the NOD mouse model (Stephen Benedict) - Clinic...

Elimination of T cell reactivity to pancreatic β cells and partial preservation of β cell activity by peptide blockade of LFA-1:ICAM-1 interaction in the NOD mouse model (Stephen Benedict) - Clinic... | AUTOIMMUNITY | Scoop.it
Abby L. Dotson, Lesya Novikova, Lisa Stehno-Bittel, Stephen H. Benedict
Clinical Immunology, Volume 148, Issue 2, August 2013, Pages...
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Scooped by Gilbert C FAURE
May 22, 2013 2:46 PM
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Newly discovered immune protein has potential to stop or reverse type 1 diabetes - News-Medical.net

Newly discovered immune protein has potential to stop or reverse type 1 diabetes
News-Medical.net
The research was published today in the journal Nature Immunology.
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Scooped by Gilbert C FAURE
April 7, 2013 9:01 AM
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“Silent” B cells trigger autoimmunity | VUMC Reporter | Vanderbilt ...

“Silent” B cells trigger autoimmunity | VUMC Reporter | Vanderbilt ... | AUTOIMMUNITY | Scoop.it
Silent” B cells trigger autoimmunity. Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.
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Scooped by Gilbert C FAURE
February 23, 2013 6:53 AM
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Proinsulin/Insulin Autoantibodies Measured With ... - Diabetes Care

OBJECTIVE We evaluated a novel electrochemiluminescent assay for insulin/proinsulin autoantibodies (ECL-IAA) as a new marker of the onset of islet autoimmunity and as a predictor of type 1 diabetes. RESEARCH DESIGN ...
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Scooped by Gilbert C FAURE
February 9, 2013 3:31 PM
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Antibody cross-reactivity and the viral etiology of type 1 diabetes - Coppieters - The Journal of Pathology - Wiley Online Library

Antibody cross-reactivity and the viral etiology of type 1 diabetes - Coppieters - The Journal of Pathology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Antibody cross-reactivity and the viral etiology of type 1 diabetes http://t.co/ewlZ180g
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Scooped by Gilbert C FAURE
February 9, 2013 3:54 AM
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Tumor necrosis factor receptor 2 involved in renal decline in diabetes - News-Medical.net

Tumor necrosis factor receptor 2 involved in renal decline in diabetes News-Medical.net Researchers have found that circulating levels of tumor necrosis factor receptor 2 (TNF-R2) are independently associated with the development of chronic kidney...
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Scooped by Gilbert C FAURE
January 23, 2013 2:21 PM
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Immune cell death defects linked to autoimmune diseases - EurekAlert (press release)

Immune cell death defects linked to autoimmune diseases - EurekAlert (press release) | AUTOIMMUNITY | Scoop.it
Immune cell death defects linked to autoimmune diseases EurekAlert (press release) Melbourne researchers have discovered that the death of immune system cells is an important safeguard against the development of diseases such as type 1 diabetes,...
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Scooped by Gilbert C FAURE
January 13, 2013 8:52 AM
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Methods For Detecting Insulin Autoantibody

The present invention provides methods for detecting insulin autoantibody. Such methods can be used, for example, to predict susceptibility of and/or diagnose the presence of Type 1 diabetes in a subject.
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Scooped by Gilbert C FAURE
December 27, 2012 8:36 AM
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Autoantibodies Found in 10% of Adult-Onset Diabetes Patients - Medscape

Medscape
Autoantibodies Found in 10% of Adult-Onset Diabetes Patients
Medscape
These included GADA in 8.8%, insulinoma-associated antigen-2 autoantibodies in 2.3%, and zinc-transporter 8 autoantibodies in 1.8%.
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Scooped by Gilbert C FAURE
December 22, 2012 4:02 AM
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WO2012172151A2 ISOLATED ANTIGEN PEPTIDE DERIVED FROM S100-BETA PROTEIN, IDENTIFICATION METHOD AND USE THEREOF IN THE PREVENTION, TREATMENT, DIAGNOSIS AND/OR MONITORING OF TYPE 1 DIABETES

WO2012172151A2 ISOLATED ANTIGEN PEPTIDE DERIVED FROM S100-BETA PROTEIN, IDENTIFICATION METHOD AND USE THEREOF IN THE PREVENTION, TREATMENT, DIAGNOSIS AND/OR MONITORING OF TYPE 1 DIABETES | AUTOIMMUNITY | Scoop.it
WIPO patent: The invention relates to an isolated antigen peptide derived from S100-beta protein, in which the peptide is bound to a class II MHC molecule.
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Scooped by Gilbert C FAURE
December 19, 2012 1:34 PM
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The environment and the origins of islet autoimmunity and Type 1 diabetes - Eringsmark Regnéll - Diabetic Medicine - Wiley Online Library

The environment and the origins of islet autoimmunity and Type 1 diabetes - Eringsmark Regnéll - Diabetic Medicine - Wiley Online Library | AUTOIMMUNITY | Scoop.it
The environment and the origins of islet autoimmunity and Type 1 diabetes: Abstract
Type 1 diabetes involves the... http://t.co/ATDmMpyj
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