AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
January 10, 2013 3:07 PM
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Naturally occurring α-synuclein autoantibody levels are lower in patients with Parkinson disease

Naturally occurring α-synuclein autoantibody levels are lower in patients with Parkinson disease | AUTOIMMUNITY | Scoop.it
Using a well-validated assay, authors detected reduced α-Syn-nAbs levels in patients with PD compared to patients with AD and HC. The assay did not achieve criteria for use as a diagnostic tool to reliably distinguish PD from HC.
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Scooped by Gilbert C FAURE
January 5, 2013 2:20 PM
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Angiotensin Receptor Agonistic Autoantibody-Med... [Hypertension. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 22, 2012 3:04 PM
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Celiac Disease — NEJM

Celiac disease is characterized by a broad range of clinical presentations, a specific serum autoantibody response, and variable damage to the small-intestinal mucosa.1 ...
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Scooped by Gilbert C FAURE
December 19, 2012 1:49 PM
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Arthritis Research & Therapy | Abstract | Autoantibody-mediated ...

The effector functions of immunoglobulin G (IgG) are mediated by interaction of its Fc region with Fc receptors (FcgammaRs) and/or the complement system. The three main pathways of complement activation converge at C3.
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Scooped by Gilbert C FAURE
December 14, 2012 1:20 PM
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Autoimmune Polyglandular Syndrome Type 3 with Anorexia

Autoimmune Polyglandular Syndrome Type 3 with Anorexia | AUTOIMMUNITY | Scoop.it
GAD autoantibody and ICA were positive, and he was diagnosed with slowly progressive type 1 diabetes mellitus (SPIDDM). Thyroid autoantibodies were positive. According to these findings, he was diagnosed with autoimmune ...
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Scooped by Gilbert C FAURE
December 6, 2012 2:52 PM
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ScienceDirect.com - Autoimmunity Reviews - TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systemat...

ScienceDirect.com - Autoimmunity Reviews - TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systemat... | AUTOIMMUNITY | Scoop.it
TSH receptor autoantibody immunoassay in patients with Graves' disease http://t.co/xLsmLbey...
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Scooped by Gilbert C FAURE
November 14, 2012 3:10 PM
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B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus–Prone Mice

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus–Prone Mice | AUTOIMMUNITY | Scoop.it
Autoim.systemic lupus erythematosus: B cell TLR7 expression →anti-RNA autoantibody production and exacerbates #ds http://t.co/FvtTlOTf...
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Scooped by Gilbert C FAURE
November 12, 2012 10:36 AM
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Kinase inhibitors for diseases in the immune system

"As a proof-of-principle that PI3Kδ inhibitors can inhibit B cell-mediated autoimmune reactions in vivo, we showed that administering IC87114 to rats reduces autoantibody production in a model of collagen-induced arthritis ...
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Scooped by Gilbert C FAURE
October 30, 2012 8:47 AM
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Autoantibody aids identification of hyperexcitability disorders - News-Medical.net

Autoantibody aids identification of hyperexcitability disordersNews-Medical.netBy Sally Robertson, medwireNews Reporter.
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Scooped by Gilbert C FAURE
October 17, 2012 2:57 AM
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WO2012139051A2 AUTOANTIBODY BIOMARKERS FOR IGA NEPHROPATHY

WO2012139051A2 AUTOANTIBODY BIOMARKERS FOR IGA NEPHROPATHY | AUTOIMMUNITY | Scoop.it
WIPO patent: Aspects of the present invention include methods for diagnosing and monitoring IgAN in a subject.
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Scooped by Gilbert C FAURE
October 14, 2012 3:29 AM
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Editorial: Natural killer cell-mediated augmentation of autoantibody production? - Journal of Leukocyte Biology (subscription)

Editorial: Natural killer cell-mediated augmentation of autoantibody production?Journal of Leukocyte Biology (subscription)Editorial: Natural killer cell-mediated augmentation of autoantibody production?
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Scooped by Gilbert C FAURE
October 13, 2012 4:53 AM
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A novel autoantibody against fibronectin leucine-rich transmembrane

Anti-endothelial cell antibodies (AECAs) are thought to be critical for vasculitides in collagen diseases, but most were directed against molecules localized within the cell and not expressed on the cell surface.
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Scooped by Gilbert C FAURE
October 13, 2012 4:52 AM
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Autoantibody detection in bullous pemphigoid: Clinical evaluation of ...

Bullous pemphigoid (BP) is an autoimmune blistering skin disease. Autoantibodies to BP180 and BP230 can be detected by indirect immunofluorescence (IIF)...
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Scooped by Gilbert C FAURE
January 8, 2013 1:59 PM
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Autoantibody-mediated complement C3a receptor a... [Hypertension. 2012] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 29, 2012 7:02 AM
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ScienceDirect.com - International Journal of Cardiology - A pilot-controlled study of myeloperoxidase-specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) in the coronary circulation

http://t.co/vj69QRXR (A pilot-controlled study of myeloperoxidase-specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) in coronary
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Scooped by Gilbert C FAURE
December 22, 2012 3:03 PM
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B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production ...

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease characterized by the production of antinuclear autoantibodies. Antinuclear autoantibody development is recognized as one of the initial stages of ...
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Scooped by Gilbert C FAURE
December 19, 2012 1:49 PM
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Clinical and Histological Features of Autoantibody ... - MDLinx

Clinical and Histological Features of Autoantibody ... - MDLinx | AUTOIMMUNITY | Scoop.it
The study aimed to define the clinical features of Chinese patients with autoantibody–negative autoimmune hepatitis (AIH), and to refine the diagnosis and management of these atypical patients. Autoantibody–negative AIH is ...
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Scooped by Gilbert C FAURE
December 11, 2012 11:17 AM
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Genalyte Awarded $500000 SBIR Grant To Develop Multiplexed Assays For ... - Sacramento Bee

Genalyte Awarded $500000 SBIR Grant To Develop Multiplexed Assays For ... - Sacramento Bee | AUTOIMMUNITY | Scoop.it
Genalyte Awarded $500000 SBIR Grant To Develop Multiplexed Assays For ...Sacramento BeeIt will then expand the approach to profile autoantibody response by multiple criteria, which is expected to enhance the ability of researchers and clinicians to...
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Scooped by Gilbert C FAURE
December 6, 2012 2:51 PM
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ScienceDirect.com - Autoimmunity Reviews - Diagnostic accuracy and predictive value of extended autoantibody profile in systemic sclerosis

ScienceDirect.com - Autoimmunity Reviews - Diagnostic accuracy and predictive value of extended autoantibody profile in systemic sclerosis | AUTOIMMUNITY | Scoop.it
RT @ImmunologyNews: Diagnostic accuracy and predictive value of extended autoantibody profile in systemic sclerosis http://t.co/sy4KPl88...
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Scooped by Gilbert C FAURE
November 14, 2012 3:02 PM
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Differences in Autoantibody Profiles and Disease Activity and Damage Scores Between Childhood- and Adult-Onset Systemic Lupus Erythematosus: A Meta-Analysis

Seminars in Arthritis and Rheumatism, Volume 42, Issue 3, Pages 271-280, December 2012, Authors:Brieanna Livingston, BSc Hon; Ashley Bonner, BSc Math; Janet Pope, MD, MPH, FRCPC (Differences in Autoantibody Profiles and Disease Activity and Damage...
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Scooped by Gilbert C FAURE
November 8, 2012 9:31 AM
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Novel cerebrospinal fluid and serum autoantibody... [J Neurochem. 2012] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
October 18, 2012 3:02 PM
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Triggers, Drivers and Modifying Factors in Type 1 Diabetes | Health ...

Triggers, Drivers and Modifying Factors in Type 1 Diabetes | Health ... | AUTOIMMUNITY | Scoop.it
When studying families with more than one child experiencing seroconversion to autoantibody positivity, we have noticed that the autoantibodies rarely appear simultaneously in seroconverting siblings (28).
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Scooped by Gilbert C FAURE
October 16, 2012 10:06 AM
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Bacteria as an Environmental Trigger of Type 1 Diabetes | Health-e ...

Bacteria as an Environmental Trigger of Type 1 Diabetes | Health-e ... | AUTOIMMUNITY | Scoop.it
A small U.S.-Finnish study including four DIPP children who eventually progressed to clinical T1D and four matched autoantibody-negative controls studied the intestinal microbiome in stool samples obtained before and at ...
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Scooped by Gilbert C FAURE
October 13, 2012 4:53 AM
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Female mouse fetal loss mediated by maternal autoantibody

It represents a novel mechanism by which maternal autoantibodies can severely affect fetal health in a gender-specific fashion and raises the question of how many maternal antibodies affect brain development or exhibit ...
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Scooped by Gilbert C FAURE
October 13, 2012 4:53 AM
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Autoantibody profiling to follow evolution of lupus syndromes

Identification of patients who are in early stages of lupus is currently done through clinical evaluation and is not greatly facilitated by available diagnostic tests.
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