AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
April 12, 2013 9:45 AM
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HLA-A*24 Is an Independent Predictor of 5-Year Progression to Diabetes in Autoantibody-Positive First-Degree Relatives of Type 1 Diabetic Patients

HLA-A*24 IIndependent Predictor of 5-Year Prog 2 Di in Autoantibody-Positive First-Degree Relatives of T1 Patients http://t.co/Ksu1wup0sq
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Scooped by Gilbert C FAURE
April 5, 2013 1:52 PM
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Cell Reports - Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells

RT @ImmunityCP: Online @CellReports IgM-AIM complexes provide a link between obesity and autoimmunity http://t.co/OGV0ekaAvC
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Scooped by Gilbert C FAURE
March 29, 2013 4:12 PM
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High-Throughput Screening for Native Autoantigen–Autoantibody Complexes Using Antibody Microarrays - Journal of Proteome Research (ACS Publications)

High-Throughput Screening for Native Autoantigen–Autoantibody Complexes Using Antibody Microarrays - Journal of Proteome Research (ACS Publications) | AUTOIMMUNITY | Scoop.it
High-Throughput Screening for Native Autoantigen–Autoantibody
Complexes Using Antibody Microarrays: Journal of... http://t.co/wQlC2nGvvm
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Scooped by Gilbert C FAURE
March 8, 2013 1:41 PM
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Prediagnostic Breast Cancer Autoantibody Signatures

We assessed the autoantibody repertoire of a mouse model engineered to develop breast cancer and the repertoire of autoantibodies in human plasmas collected at a preclinical time point and at the time of clinical diagnosis ...
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Scooped by Gilbert C FAURE
March 3, 2013 12:39 PM
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Takeda and Resolve Therapeutics Enter Autoimmune Partnership ...

Takeda and Resolve Therapeutics Enter Autoimmune Partnership ... | AUTOIMMUNITY | Scoop.it
These compounds target the degradation and elimination of autoantibody-containing immune complexes, which are thought to be the most proximal pathophysiological trigger of lupus. Resolve will conduct all development ...
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Scooped by Gilbert C FAURE
February 14, 2013 12:02 PM
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Humoral responses to islet antigen-2 and zinc transporter 8 are ...

HLA-A*24 genotype and autoantibody responses to insulin (IAA), glutamate decarboxylase (GADA), IA-2, IA-2β and ZnT8 were analysed in samples collected from patients with recent-onset type 1 diabetes. After correction for ...
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Scooped by Gilbert C FAURE
February 9, 2013 1:52 PM
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Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus

Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus | AUTOIMMUNITY | Scoop.it
Endocrinology Medical Article: Zinc transporter 8 autoantibody (ZnT8A) could help differentiate latent autoimmune diabetes in adults (LADA) from phenotypic type 2 diabetes mellitus (Zinc transporter 8 autoantibody (ZnT8A) could help differentiate...
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Scooped by Gilbert C FAURE
January 27, 2013 4:10 AM
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WO2013012478A1 DIAGNOSIS AND TREATMENT OF AUTOANTIBODY-MEDIATED HEART DISEASE

WO2013012478A1 DIAGNOSIS AND TREATMENT OF AUTOANTIBODY-MEDIATED HEART DISEASE | AUTOIMMUNITY | Scoop.it
WIPO patent: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 antibodies to cardiac autoantigens.
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Scooped by Gilbert C FAURE
January 24, 2013 2:37 PM
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Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia

Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia | AUTOIMMUNITY | Scoop.it
Endocrinology Medical Article: Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia (Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasi...
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Scooped by Gilbert C FAURE
January 23, 2013 1:50 PM
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Canadian Pediatric Lupus Severity Varies With Ethnicity - Doctors Lounge

Canadian Pediatric Lupus Severity Varies With Ethnicity - Doctors Lounge | AUTOIMMUNITY | Scoop.it
Canadian Pediatric Lupus Severity Varies With Ethnicity Doctors Lounge The researchers found that disease manifestations (malar rash, arthritis, serositis, renal disease), autoantibody profiles, and severity of disease expression differed by...
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Scooped by Gilbert C FAURE
January 18, 2013 2:42 PM
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Elevated serum and synovial fluid TNF-like ligand 1A (TL1A) is associated with autoantibody production in patients with rheumatoid arthritis, Scandinavian Journal of Rheumatology, Informa Healthcare

Elevated serum and synovial fluid TNF-like ligand 1A (TL1A) is associated with autoantibody production in patients with rheumatoid arthritis, Scandinavian Journal of Rheumatology, Informa Healthcare | AUTOIMMUNITY | Scoop.it
Elevated serum and synovial fluid TNF-like ligand 1A (TL1A) is associated with autoantibody productio... http://t.co/JecVmNVs #antiaging
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Scooped by Gilbert C FAURE
January 18, 2013 2:41 PM
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JNI | Abstract | Two new cases of anti-Ca (anti-ARHGAP26/GRAF) autoantibody-associated cerebellar ataxia

Recently, we discovered a novel serum and cerebrospinal fluid (CSF) autoantibody (anti-Ca) to Purkinje cells in a patient with autoimmune cerebellar ataxia (ACA) and identified the RhoGTPase-activating protein 26 (ARHGAP26; alternative designations...
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Scooped by Gilbert C FAURE
January 13, 2013 8:52 AM
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Methods For Detecting Insulin Autoantibody

The present invention provides methods for detecting insulin autoantibody. Such methods can be used, for example, to predict susceptibility of and/or diagnose the presence of Type 1 diabetes in a subject.
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Scooped by Gilbert C FAURE
April 8, 2013 2:33 PM
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The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus

The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus - up-to-the-minute news and headlines.
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Scooped by Gilbert C FAURE
April 4, 2013 2:30 PM
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Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara

Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara - up-to-the-minute news and headlines.
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Scooped by Gilbert C FAURE
March 11, 2013 4:29 PM
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Predominant Autoantibody Production by Early Human B Cell Precursors

メモ Predominant Autoantibody Production by Early Human B Cell Precursors http://t.co/W4ScF043be
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Scooped by Gilbert C FAURE
March 6, 2013 2:40 AM
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What is TrialNet Screening | TrialNet screening

What is TrialNet Screening | TrialNet screening | AUTOIMMUNITY | Scoop.it
RT @T1D_TrialNet: Have you told your relatives about TrialNet autoantibody testing? Send them a reminder! http://t.co/12sQE5kMPU
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Scooped by Gilbert C FAURE
February 15, 2013 6:34 AM
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Rheumatology News - Autoantibody stabilization of the classical ...

Rheumatology News - Autoantibody stabilization of the classical ... | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: Autoantibody stabilization of the classical pathway C3 convertase leading to C3 deficiency and Neisserial sepsis: C4 nephritic factor revisited.
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Scooped by Gilbert C FAURE
February 11, 2013 7:34 AM
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IL-10-producing regulatory B cells (B10 cells) in autoimmune disease - 7thSpace Interactive (press release)

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
7thSpace Interactive (press release)
Nevertheless, in addition to autoantibody production, B cells have other functions potentially relevant to autoimmunity.
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Scooped by Gilbert C FAURE
February 3, 2013 8:16 AM
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JCI - Peptide-mediated desmoglein 3 crosslinking prevents ...

TP abrogated autoantibody-mediated interference of DSG3 transinteraction and blocked acantholysis in vivo. Previously, we designed and extensively characterized a peptide effectively blocking autoantibody-induced loss of ...
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Scooped by Gilbert C FAURE
January 26, 2013 2:36 AM
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Internal Medicine News Article | Autoantibody against WD repeat ...

Internal Medicine News Article | Autoantibody against WD repeat ... | AUTOIMMUNITY | Scoop.it
Internal Medicine Medical Article: Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia.
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Scooped by Gilbert C FAURE
January 24, 2013 2:18 PM
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Arthritis Research & Therapy | Abstract | Lots of autoantibodies ...

New data now show in an unbiased way that, in patients with early SLE, an increasing number of autoantibody specificities does not only affect typical SLE associated antibodies, but also a variety of other autoantibodies, such ...
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Scooped by Gilbert C FAURE
January 22, 2013 2:20 PM
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Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese

RT @Bipolar_Blogs: Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Ho... http://t.co/2qcrs2eg
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Scooped by Gilbert C FAURE
January 18, 2013 2:41 PM
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JNI | Abstract | The history of neuromyelitis optica

The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO).
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Scooped by Gilbert C FAURE
January 14, 2013 2:17 PM
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JCI - Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering

JCI - Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering http://t.co/G1aEzJcu #jci
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