AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
September 26, 2013 8:00 AM
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EASD Virtual Meeting

EASD Virtual Meeting | AUTOIMMUNITY | Scoop.it
RT @EASDnews: #EASD2013 New frontiers in autoantibody epidemiology - http://t.co/xEuR5qVLWa
Gilbert C FAURE's insight:

we'll check how long it will be available

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Scooped by Gilbert C FAURE
September 25, 2013 2:43 PM
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Serum Anti-CCNY Autoantibody Is an Independent Prognosis ...

Serum Anti-CCNY Autoantibody Is an Independent Prognosis ... | AUTOIMMUNITY | Scoop.it
Disease Markers is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies related to all aspects of disease markers.
Gilbert C FAURE's insight:

in NSCLC...

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Scooped by Gilbert C FAURE
September 6, 2013 7:38 AM
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GABAB receptor autoantibody frequency in service serologic evaluation

GABAB receptor autoantibody frequency in service serologic evaluation | AUTOIMMUNITY | Scoop.it
RT @GreenJournal: GABAB receptor autoantibody frequency in service serologic evaluation
http://t.co/Wyd9qA1OEp #Neurology http://t.co/GPf…;
Gilbert C FAURE's curator insight, March 4, 2014 10:02 AM

Conclusion: GABABR autoantibody is a marker of an uncommon but treatable paraneoplastic neurologic disorder, usually occurring in the setting of limbic encephalitis and SCLC.

Scooped by Gilbert C FAURE
August 28, 2013 10:50 AM
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Multiple Sclerosis Research: Autoantibody in spinal fluids

OBJECTIVE:To profile the reactivity of CSF-derived immunoglobulin from patients with multiple sclerosis (MS) against a large panel of antigens, to identify disease-specific reactivities. METHODS: CSF from subjects with MS  ...
Gilbert C FAURE's insight:

looking for autoantibodies in CSF...

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Scooped by Gilbert C FAURE
August 16, 2013 2:39 PM
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MACL Launches Blood Test to Aid in the Early Detection of Lung Cancer - San Francisco Chronicle (press release)

MACL Launches Blood Test to Aid in the Early Detection of Lung Cancer - San Francisco Chronicle (press release) | AUTOIMMUNITY | Scoop.it
MACL Launches Blood Test to Aid in the Early Detection of Lung Cancer
San Francisco Chronicle (press release)
Seventeen peer-reviewed publications support the EarlyCDT® autoantibody platform, click here.
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Scooped by Gilbert C FAURE
July 30, 2013 1:08 PM
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Autoantibody prevalence in active tuberculosis: reactive or pathognomonic? -- Shen et al. 3 (7) -- BMJ Open

Research News: Autoantibody prevalence in active Tuberculosis: reactive or pathognomonic? #BMJ: http://t.co/1Ic8EATxlz
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Scooped by Gilbert C FAURE
July 14, 2013 3:52 AM
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p38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity

Whether autoantibody-antigen interactions can trigger signaling pathways (such as p38 MAPK) that are tightly linked to the secretion of inflammatory mediators which may perpetuate inflammation and tissue damage in pemphigus remains unclear.
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Scooped by Gilbert C FAURE
June 28, 2013 3:13 AM
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WO2013096793A1 GAIN-OF-FUNCTION ADAMTS13 VARIANTS RESISTANT TO AUTOANTIBODY INHIBITION AND METHODS OF USE THEREOF

WO2013096793A1 GAIN-OF-FUNCTION ADAMTS13 VARIANTS RESISTANT TO AUTOANTIBODY INHIBITION AND METHODS OF USE THEREOF | AUTOIMMUNITY | Scoop.it
WIPO patent: Compositions and methods for the treatment of thrombotic thrombocytopenic purpura are disclosed. (WO2013096793A1 Gain-of-function Adamts13 Variants Resistant To Autoantibody Inhibition And ...
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Scooped by Gilbert C FAURE
June 25, 2013 9:55 AM
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The spectrum of MOG autoantibody-associated demyelinating diseases : Abstract : Nature Reviews Neurology

And Reindl et al. review the spectrum of MOG antibody-associated demyelinating diseases http://t.co/tP5Iz4v36e (£) #newfromnrneurol
Gilbert C FAURE's curator insight, March 4, 2014 10:00 AM

Myelin oligodendrocyte glycoprotein (MOG) has been identified as a target of demyelinating autoantibodies in animal models of inflammatory demyelinating diseases of the CNS, such as multiple sclerosis (MS). Numerous studies have aimed to establish a role for MOG antibodies in patients with MS, although the results have been controversial. Cell-based immunoassays using MOG expressed in mammalian cells have demonstrated the presence of high-titre MOG antibodies in paediatric patients with acute disseminated encephalomyelitis, MS, aquaporin-4-seronegative neuromyelitis optica, or isolated optic neuritis or transverse myelitis, but only rarely in adults with these disorders. These studies indicate that MOG antibodies could be associated with a broad spectrum of acquired human CNS demyelinating diseases. This Review article discusses the current literature on MOG antibodies, their potential clinical relevance, and their role in the pathogenesis of MOG antibody-associated demyelinating disorders.

Scooped by Gilbert C FAURE
May 4, 2013 1:35 AM
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Metaanalysis of the Association of Smoking and PTPN22 R620W Genotype on Autoantibody Status and Radiological Erosions in Rheumatoid Arthritis

Association of Smoking and PTPN22 R620W on Autoantibody Status and Rad. Erosions in Rheumatoid Arthritis. #mdart #md http://t.co/jbGiUJkdfk
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Scooped by Gilbert C FAURE
April 28, 2013 3:14 AM
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Research: Myelin antibodies predicting MS - Multiple Sclerosis ...

Research: Myelin antibodies predicting MS - Multiple Sclerosis ... | AUTOIMMUNITY | Scoop.it
Because autoantibodies may contribute to the pathogenesis of both diseases, we sought to identify autoantibody biomarkers that are capable of distinguishing them. Methods: We used custom antigen arrays to profile ...
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Scooped by Gilbert C FAURE
April 19, 2013 2:38 PM
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Your Autoantibody 'Profile' Might Someday Help Spot Illness

Your Autoantibody 'Profile' Might Someday Help Spot Illness | AUTOIMMUNITY | Scoop.it
Differences showed up in study of people with conditions including Alzheimer's, breast cancer THURSDAY, April 18 (HealthDay News) -- Human blood conta...
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Scooped by Gilbert C FAURE
April 12, 2013 9:46 AM
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Frontiers | Self-Organized Criticality Theory and the Expansion of PD-1-Positive Effector CD4 T Cells: Search for Autoantibody-Inducing CD4 T Cells | Frontiers in T Cell Biology

Frontiers | Self-Organized Criticality Theory and the Expansion of PD-1-Positive Effector CD4 T Cells: Search for Autoantibody-Inducing CD4 T Cells | Frontiers in T Cell Biology | AUTOIMMUNITY | Scoop.it
Frontiers | Self-Organized Criticality Theory and the Expansion of PD-1-Positive Effector CD4 T Cells: Search for Autoantibody-Inducing CD4 T Cells | Frontiers in T Cell Biology publishes articles on the most outstanding discoveries across the...
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Scooped by Gilbert C FAURE
September 26, 2013 7:59 AM
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Science Codex Article on Development of Autoimmunity in Patients ...

Science Codex Article on Development of Autoimmunity in Patients ... | AUTOIMMUNITY | Scoop.it
"When associated with CVID, a single TACI mutation predicts the development of autoantibody-mediated autoimmune disease, whereas patients with two mutated alleles are mostly spared clinical autoimmune conditions, ...
Gilbert C FAURE's insight:

go to the JCI paper

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Scooped by Gilbert C FAURE
September 13, 2013 1:58 PM
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A Study on Detection of Dickkopf-1 Autoantibody in Serums of ...

Background: lung cancer is the most common malignant tumor,Currently,there are many clinical methods to detect lung cancer,but these methods are not very perfect in diagnosis、treatment and prognosis of NSCLC.
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Scooped by Gilbert C FAURE
September 4, 2013 11:06 AM
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Multiple Sclerosis Research: Autoantibody in spinal fluids

Multiple Sclerosis Research: Autoantibody in spinal fluids | AUTOIMMUNITY | Scoop.it
Hunting for antibodies in tissue fluids is a pass-time for immunologists. This study adds yet one more to the growing list, a bit of a light chain of antibodies, but as ever, this occurs in a minority of Mers so what is the real ...
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Scooped by Gilbert C FAURE
August 16, 2013 2:41 PM
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Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types - Online First - Springer

Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types - Online First - Springer | AUTOIMMUNITY | Scoop.it
Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types http://t.co/M6gBQUgZMg #Springer
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Scooped by Gilbert C FAURE
July 31, 2013 12:47 PM
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Frontiers | Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens | Frontiers in Inflammation

Frontiers | Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens | Frontiers in Inflammation | AUTOIMMUNITY | Scoop.it
Frontiers | Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens | Frontiers in Inflammation publishes articles on the most outstanding discoveries across the research spectrum...
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Scooped by Gilbert C FAURE
July 14, 2013 8:54 AM
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Arthritis Research & Therapy | Abstract | What autoantibody tests ...

Anti-Th/To autoantibodies have been recognized as serological markers of systemic sclerosis (SSc) for more than 20 years. However, validated immunoassay kits to test this specificity have not been commercially available.
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Scooped by Gilbert C FAURE
July 14, 2013 3:13 AM
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Patterns of ß-cell Autoantibody Appearance and Genetic ... - Diabetes

In a prospective birth cohort comprising children with HLA-conferred susceptibility to type 1 diabetes (T1D) the pattern of autoantibody appearance was analyzed in 520 children with advanced β-cell autoimmunity associated ...
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Scooped by Gilbert C FAURE
June 26, 2013 6:40 AM
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MEDLAB_ISSUE_2_2013

MEDLAB_ISSUE_2_2013 | AUTOIMMUNITY | Scoop.it
MEDLAB_ISSUE_2_2013 (We look at new autoantibody markers for neurological diseases http://t.co/dk6e6V8t7S #medlab)
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Scooped by Gilbert C FAURE
June 23, 2013 8:31 AM
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Insights into Veterinary Endocrinology: Iatrogenic Hyperthyroidism in ...

Insights into Veterinary Endocrinology: Iatrogenic Hyperthyroidism in ... | AUTOIMMUNITY | Scoop.it
The most common thyroid autoantibody detected in dogs are thyroglobulin autoantibodies (2-5). These autoantibodies do not interfere with the standard measurement of serum total or free thyroid hormone concentrations.
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Scooped by Gilbert C FAURE
May 2, 2013 3:09 PM
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Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma

Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma | AUTOIMMUNITY | Scoop.it
Oncology Medical Article: Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma (Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinom...
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Scooped by Gilbert C FAURE
April 27, 2013 4:14 AM
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Guest blog by Giuseppe Matarese: Unveiling the molecular basis for obesity-associated autoantibody responses | Cell.com Blog

Guest blog by Giuseppe Matarese: Unveiling the molecular basis for obesity-associated autoantibody responses | Cell.com Blog | AUTOIMMUNITY | Scoop.it
Obesity as an autoimmune disorder? http://t.co/Ibha5Q9Hqv
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Scooped by Gilbert C FAURE
April 14, 2013 1:55 PM
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Pathomechanisms of Autoantibody Production against the Nervous System - ProHealth

Pathomechanisms of Autoantibody Production against the Nervous System - ProHealth | AUTOIMMUNITY | Scoop.it
Pathomechanisms of Autoantibody Production against the Nervous System ProHealth Editor's Comment: This study is the most recent addition to the body of evidence that infections may be precipitating factors in the later development of chronic...
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