AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
January 14, 2015 1:25 PM
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Neuromuscular junction as Achilles' heel: Yet another autoantibody?

Neuromuscular junction as Achilles' heel: Yet another autoantibody? | AUTOIMMUNITY | Scoop.it
Neuromuscular junction as Achilles' heel: Yet another autoantibody? http://t.co/AdwEEvTyjB
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Scooped by Gilbert C FAURE
January 6, 2015 3:58 PM
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Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients - ...

Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients - ... | AUTOIMMUNITY | Scoop.it
Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant... http://t.co/3Ayt628Gym
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Suggested by Société Francaise d'Immunologie
January 6, 2015 3:54 PM
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Natural Anti-Intestinal Goblet Cell Autoantibody Production from Marginal Zone B Cells [IMMUNE SYSTEM DEVELOPMENT]

Expression of a germline VH3609/D/JH2 IgH in mice results in the generation of B1 B cells with anti-thymocyte/Thy-1 glycoprotein autoreactivity by coexpression of Vk21-5/Jk2 L chain leading to production of serum IgM natural autoantibody.
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Scooped by Gilbert C FAURE
December 17, 2014 1:50 PM
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Mining the human autoantibody repertoire: isolation of potent IL17A... - PubMed - NCBI

MAbs. 2014 Nov 1:0. [Epub ahead of print]
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Suggested by Société Francaise d'Immunologie
December 2, 2014 2:12 PM
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C4 Deficiency Is a Predisposing Factor for Streptococcus pneumoniae-Induced Autoantibody Production [AUTOIMMUNITY]

Reductions in C4 levels may predispose individuals to infection with encapsulated bacteria as well as autoimmunity. In this study, we examined the role C4 has in protection against Streptococcus pneumoniae–induced autoimmunity.
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Scooped by Gilbert C FAURE
November 26, 2014 2:16 PM
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Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study

RT @NatureRevEndo: New #genetic risk factors for autoantibody positivity identified in patients with #T1DM http://t.co/kWDPO4Nj03 #diabete…
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Scooped by Gilbert C FAURE
November 20, 2014 2:42 PM
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Anti-Ribosomal P Antibody Is a Key Autoantibody Associated with Complications of NP-SLE with High-Levels of CSF IL-8 - ACR Abstracts

Anti-Ribosomal P Antibody Is a Key Autoantibody Associated with Complications of NP-SLE with High-Levels of CSF IL-8 - ACR Abstracts | AUTOIMMUNITY | Scoop.it
Background/Purpose: Complications of neuropsychiatric systemic lupus erythematosus (NP-SLE) are associated with the morbidity and mortality of patients with SLE.
Gilbert C FAURE's curator insight, November 21, 2014 10:03 AM

among  searchable ACR abstracts 2012-2013-2014

 

 

Scooped by Gilbert C FAURE
November 11, 2014 2:30 PM
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Autoantibody profiling for lung cancer screening lo... [PLoS One. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
November 7, 2014 7:54 AM
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Engineering mice to identify autoreactive T-cell antigens - Nature.com

Engineering mice to identify autoreactive T-cell antigens Nature.com Whereas autoantibody targets are relatively easy to identify in autoimmune diseases, the autoantigen targets of pathogenic T cells that might be central to rheumatoid arthritis...
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Scooped by Gilbert C FAURE
October 26, 2014 2:46 PM
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Autoantibody-mediated bone loss. [Curr Osteoporos Rep. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

For many years, the involvement of autoantibodies in bone resorption has merely been attributed to enhanced tissue infiltration and the production of inflammatory cytokines that promote osteoclastogenesis. However, recent research provides evidence for a direct activation of osteoclasts and their precursors by autoantibodies, which is independent of inflammation. The depletion of B-cells with rituximab that substantially reduces autoantibody levels seems to be as effective as the well-established treatment with tumor necrosis factor-antagonists in RA patients that do not respond to methotrexate, highlighting the significance of autoantibodies for RA and bone loss.

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Scooped by Gilbert C FAURE
October 17, 2014 1:57 PM
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Spleen Tyrosine Kinase Inhibition Attenuates Autoantibody Production and Reverses Experimental Autoimmune GN

#Spleen Tyrosine Kinase Inhibition Attenuates #Autoantibody Production and Reverses Experimental Autoimmune #GN... http://t.co/17cv0SvbHU
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Scooped by Gilbert C FAURE
October 13, 2014 1:53 PM
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New autoantibody detection technologies yield novel insights into autoimmune disease

New autoantibody detection technologies yield novel insights into autoimmune disease | AUTOIMMUNITY | Scoop.it
Purpose of reviewThe purpose of this review is to highlight recent progress in autoantibody detection technologies and descri.
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Scooped by Gilbert C FAURE
September 24, 2014 2:53 PM
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Associations between thyroid autoantibody status and abnormal pregnancy outcomes in euthyroid women - Online First - Springer

Associations between thyroid autoantibody status and abnormal pregnancy outcomes in euthyroid women - Online First - Springer | AUTOIMMUNITY | Scoop.it
Associations between thyroid autoantibody status and abnormal pregnancy outcomes in euthyroid women: Abstract
... http://t.co/vx76VqYEw2
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Scooped by Gilbert C FAURE
January 14, 2015 1:24 PM
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Decrease in Circulating Concentrations of Soluble Receptors for Advanced Glycation End Products at the Time of Seroconversion to Autoantibody Positivity in Prediabetic Children.

Decrease in Circulating Concentrations of Soluble Receptors for Advanced Glycation End Products at the Time of Seroconversion to Autoantibody Positivity in Prediabetic Children. | AUTOIMMUNITY | Scoop.it
Authors: Kirsi M Salonen, Samppa J Ryhänen, Josephine M Forbes, Danielle J Borg, Taina Härkönen, Jorma Ilonen, Olli Simell, Riitta Veijola, Per-Henrik Groop, Mikael Knip, Discipline: Medicine, Type: Journal Article...
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Scooped by Gilbert C FAURE
January 6, 2015 3:55 PM
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UKE Scientists Detect New Autoantibody

UKE Scientists Detect New Autoantibody | AUTOIMMUNITY | Scoop.it
Discovery may put an end to dialysis. Co-operation of UKE with scientists from France and the U.S.
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Scooped by Gilbert C FAURE
January 3, 2015 3:19 PM
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Clinical and Pathological Study on Patients With Primary Ant... : JCR: Journal of Clinical Rheumatology

Background: Traditionally, antineutrophil cytoplasmic autoantibody–associated vasculitis (AAV) is histologically characterized by pauci-immune glomerulonephritis.
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Scooped by Gilbert C FAURE
December 8, 2014 1:58 PM
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Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma - España - 2014 - British Journal of Dermatology - Wiley Online Library

Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma - España - 2014 - British Journal of Dermatology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis‐type IgA pemphigus associated with multip... http://t.co/nY0jI5ZQlD
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Scooped by Gilbert C FAURE
December 1, 2014 12:54 PM
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Autoimmunity: Basophils in autoimmune and inflammatory diseases - Nature.com

Autoimmunity: Basophils in autoimmune and inflammatory diseases
Nature.com
TH2 cells along with basophils (via IL-4, IL-6 and BAFF) induce B-cell activation, differentiation and autoantibody production (including IgE).
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Scooped by Gilbert C FAURE
November 24, 2014 2:05 PM
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Anti-Ribosomal P Antibody Is a Key Autoantibody...

Anti-Ribosomal P Antibody Is a Key Autoantibody... | AUTOIMMUNITY | Scoop.it
Complications of neuropsychiatric systemic lupus erythematosus (NP-SLE) are associated with the morbidity and mortality of patients with SLE.
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Scooped by Gilbert C FAURE
November 20, 2014 2:42 PM
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Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset

Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset | AUTOIMMUNITY | Scoop.it
Rheumatology Article: Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset
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Scooped by Gilbert C FAURE
November 11, 2014 2:18 PM
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A novel autoantibody against moesin in the serum of patients with M... - PubMed - NCBI

Nephrol Dial Transplant. 2014 Jun;29(6):1168-77. doi: 10.1093/ndt/gft469. Epub 2013 Dec 5. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
October 28, 2014 3:48 PM
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C4 Deficiency Is a Predisposing Factor for Streptococcus pneumoniae–Induced Autoantibody Production

C4 Deficiency Is a Predisposing Factor for Streptococcus pneumoniae–Induced Autoantibody Production http://t.co/wO5lbEHL5Y #inmuva
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Suggested by Société Francaise d'Immunologie
October 21, 2014 2:50 PM
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Pathogenic IgG Antibodies against Desmoglein 3 in Pemphigus Vulgaris Are Regulated by HLA-DRB1*04:02-Restricted T Cells [AUTOIMMUNITY]

Pemphigus vulgaris (PV) is considered as a model for an autoantibody-mediated organ-specific autoimmune disorder.
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Scooped by Gilbert C FAURE
October 13, 2014 1:57 PM
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Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Methylprednisolone Combined with MTX and DXM Intrathecal Injection - Springer

Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Methylprednisolone Combined with MTX and DXM Intrathecal Injection - Springer | AUTOIMMUNITY | Scoop.it
Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Me... http://t.co/NGWJvY96OQ #biophysics
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Scooped by Gilbert C FAURE
October 10, 2014 5:08 AM
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Analysis of Autoantibody Profiles in Osteoarthritis Using Comprehensive Protein Array Concepts - Journal of Proteome Research (ACS Publications)

Analysis of Autoantibody Profiles in Osteoarthritis Using Comprehensive Protein Array Concepts - Journal of Proteome Research (ACS Publications) | AUTOIMMUNITY | Scoop.it
#proteomics: "Analysis of Autoantibody Profiles
in Osteoarthritis
Using Comprehensive Protein Array Concepts" http://t.co/uyqdtVrYqG
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