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Scoop.it!
Latest news from South Africa, World, Politics, Entertainment and Lifestyle. The home of The Times and Sunday Times newspaper. (The hunt for an HIV vaccine has gobbled up $8-billion in the past decade with no real results. 
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Scoop.it!
The National Institute of Allergy and Infectious Diseases (NIAID) has announced that it will halt its HVTN 505 HIV vaccine trial due to a perceived lack of efficacy. A scheduled review by an independent data and safety monitoring board found that the vaccine regimen neither prevented HIV infection nor reduced viral load in vaccine recipients who became infected with HIV. The announcement will come as a blow to those hoping the HVTN 505 would be an effective intervention to stem the HIV pandemic.
HIV particle graphic by Russell Kightley Media
Ed Rybicki's insight:
And another one bites the dust...not only not effective, but suspected of increasing infection rates. VERY sad!
I am beginning to think that adenoviruses are simply useless when it comes to vectoring HIV genes for vaccine purposes.
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Beause of rampant band-wagon jumping and some ignoring of basic lessons from other lentiviruses...the Ad5 bandwagon was especially noticeable; it will be interesting to see what the new wagon will be, now that this has come to a grinding halt. Poxviruses, anyone?