Your new post is loading...
Follow, research and publish the best content
Get Started for FREE
Sign up with Facebook Sign up with X
I don't have a Facebook or a X account
Already have an account: Login
Animal Models - GEG Tech top picks
7.3K views |
+0 today
In this study, the scientists demonstrated that truncated gRNAs to 18 complementary nucleotides and Cas9 nucleases, can generate FVII gene KO mice with a significantly higher efficiency in a site-dependent manner. In addition, the off-target frequency was much lower in KO mice than in cell lines via RGN expression vector-mediated genome editing.