Local delivery for Gene Directed Enzyme Prodrug Therapy
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Local delivery for Gene Directed Enzyme Prodrug Therapy
Engineered MSCs with suicide genes delivered intra-arterially to treat various cancers. Local delivery bypasses homing issues that plagued prior GDEPT programs.
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May 19, 2022 4:44 PM
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A new theoretical upgrade could unlock vastly greater amounts of fusion power

A new theoretical upgrade could unlock vastly greater amounts of fusion power | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it
"Since the early days of fusion, we've known that if you try to increase the fuel density, at some point there would be what we call a 'disruption' — basically you totally lose the confinement, and plasma goes wherever," Ricci continued. "So in the eighties, people were trying to come up with some kind of law that could predict the maximum density of hydrogen that you can put inside a tokamak."
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May 8, 2022 3:22 PM
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Billionaire battle over fusion power: Next founder Lord Wolfson up against Jeff Bezos and Bill Gates

Billionaire battle over fusion power: Next founder Lord Wolfson up against Jeff Bezos and Bill Gates | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it
British start-up Tokamak Energy is racing to win a global battle against US billionaires to crack a scientific conundrum.
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May 5, 2022 4:56 PM
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Fuelling the Fusion Reaction

Fuelling the Fusion Reaction | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it
Deuterium can be distilled from all forms of water. It is a widely available, harmless, and virtually inexhaustible resource. In every cubic metre of seawater, for example, there are 33 grams of deuterium. Deuterium is routinely produced for scientific and industrial applications. Tritium is a fast-decaying radioelement of hydrogen which occurs only in trace quantities in nature. It can be produced during the fusion reaction through contact with lithium, however: tritium is produced, or "bred," when neutrons escaping the plasma interact with lithium contained in the blanket wall of the tokamak.
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May 4, 2022 4:02 AM
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Can the development of fusion energy be accelerated?

Can the development of fusion energy be accelerated? | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The meeting posed the question ‘Can development of fusion power be accelerated?’ We have heard enough to understand that it can be accelerated, not by pursuing a single line of development alone, but by pursuing several new ideas in parallel, and especially those based on higher field, lower aspect ratio and lower power devices. In his final round-up comments, Mike Zarnstoff gave us the good summary sentence: ‘de-risk at minimum size’.

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May 4, 2022 3:43 AM
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Tencent invests in Oxford’s First Light Fusion

Tencent invests in Oxford’s First Light Fusion | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

A business in Oxford working on nuclear fusion technology has raised $45 million from investors including Tencent, of China, to help it to research the potential of commercialising what is hoped will be a virtually limitless source of clean energy. First Light Fusion said that the funds would help it to run experiments and work on plans for a “first-of-a-kind commercial fusion energy power plant” based on its technology.

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May 4, 2022 3:39 AM
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Nuclear fusion reactors of the future coming into view

Nuclear fusion reactors of the future coming into view | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The production of 59 megajoules of energy over five seconds at the Joint European Torus – or JET – experiment in England has been called “a breakthrough” by some news outlets and caused quite a lot of excitement among physicists. But a common line regarding fusion electricity production is that it is “always 20 years away.” We are a nuclear physicist and a nuclear engineer who study how to develop controlled nuclear fusion for the purpose of generating electricity.

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May 4, 2022 3:36 AM
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DeepMind Has Trained an AI to Control Nuclear Fusion

DeepMind Has Trained an AI to Control Nuclear Fusion | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The inside of a tokamak—the doughnut-shaped vessel designed to contain a nuclear fusion reaction—presents a special kind of chaos. Hydrogen atoms are smashed together at unfathomably high temperatures, creating a whirling, roiling plasma that’s hotter than the surface of the sun. Finding smart ways to control and confine that plasma will be key to unlocking the potential of nuclear fusion, which has been mooted as the clean energy source of the future for decades. At this point, the science underlying fusion seems sound, so what remains is an engineering challenge. “We need to be able to heat this matter up and hold it together for long enough for us to take energy out of it,” says Ambrogio Fasoli, director of the Swiss Plasma Center at École Polytechnique Fédérale de Lausanne in Switzerland.

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May 4, 2022 3:34 AM
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European scientists in ‘landmark’ nuclear fusion breakthrough

European scientists in ‘landmark’ nuclear fusion breakthrough | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

A team of researchers from the Eurofusion consortium produced 59 megajoules from a sustained reaction lasting five seconds — enough power to boil about 60 kettles — in an experiment at the Joint European Torus facility in Oxford, England.

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May 4, 2022 3:27 AM
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Magnetic control of tokamak plasmas through deep reinforcement learning

Magnetic control of tokamak plasmas through deep reinforcement learning | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Nuclear fusion using magnetic confinement, in particular in the tokamak configuration, is a promising path towards sustainable energy. A core challenge is to shape and maintain a high-temperature plasma within the tokamak vessel. This requires high-dimensional, high-frequency, closed-loop control using magnetic actuator coils, further complicated by the diverse requirements across a wide range of plasma configurations. In this work, we introduce a previously undescribed architecture for tokamak magnetic controller design that autonomously learns to command the full set of control coils.

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May 4, 2022 3:25 AM
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Just around the corner

Just around the corner | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Fusion research is difficult enough without the politics. The much-vaunted concept of mimicking the Sun and generating power from nuclear fusion has been an unfulfilled promise for some 50 years. Even to get this far, researchers have had to overcome formidable technical and scientific barriers. But they hope that ITER will at last prove to doubting politicians and scientific colleagues that nuclear fusion is a viable energy source. If all goes well, funding from ITER's six international partners — China, the European Union, Japan, South Korea, Russia and the United States — could be in place this winter, allowing construction to begin in 2006, and operation in 2016.

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May 4, 2022 3:20 AM
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A nuclear fusion powered hypercar concept for the post Mars colonization era

A nuclear fusion powered hypercar concept for the post Mars colonization era | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The designer Kellen Gustine wants to make the fusion reactor ecosystem in a closely-knit environment where the mobile HB11 fusion reactor provides consistent, sustainable, and mobile energy for a single family’s home and vehicle. For now, we are going to focus on this sleek clean energy-powered vehicle which is dominated by a cabin that’s held in place by the corners which bring unprecedented 3D contrast and volume. SpaceX Fusion is built for speed and maneuverability with its single-seat or three-seater dynamics. To cool down the engine, the hollow structure is reinforced with graphene tubes which adds another dimension to the shredded look.

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May 3, 2022 3:50 AM
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Japan's first laser nuclear fusion company, EX-Fusion raises 130 million JPY in pre-seed round paving way for the development of critical components needed for commercialization of nuclear fusion

Japan's first laser nuclear fusion company, EX-Fusion raises 130 million JPY in pre-seed round paving way for the development of critical components needed for commercialization of nuclear fusion | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

EX-Fusion Inc., the first startup in Japan aimed at commercializing laser based fusion energy, announced on March 31, 2022 that it has closed a pre-seed round funding of 130 million Japanese yen. The pre-seed round was led by ANRI, a Tokyo based venture capital firm, along with Osaka University Venture Capital (OUVC) and was the first company funded within ANRI's latest ESG specific fund.

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May 3, 2022 3:48 AM
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Claiming a landmark in fusion energy, TAE Technologies sees commercialization by 2030

Claiming a landmark in fusion energy, TAE Technologies sees commercialization by 2030 | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The 20-year-old fusion energy technology developer TAE Technologies said its reactors could be operating at commercial scale by the end of the decade, thanks to its newfound ability to produce stable plasma at temperatures over 50 million degrees (nearly twice as hot as the sun).

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May 12, 2022 2:09 PM
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MIT joins a major startup backed by Bill Gates to build a viable fusion machine

MIT joins a major startup backed by Bill Gates to build a viable fusion machine | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it
The Plasma Science and Fusion Center (PSFC) at the Massachusetts Institute of Technology (MIT) has signed a new five-year agreement with Commonwealth Fusion System (CFS) to continue their collaboration on fusion energy research and education activities, an institutional press release said.
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May 7, 2022 2:31 PM
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Nuclear Fusion: Between Technology and Investment Risk

Nuclear Fusion: Between Technology and Investment Risk | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Our three speakers will focus on:

  • Investment risk – how private equity assesses risk and probability of returns when considering whether to invest in the new energy sector.
  • Technology risks – why we think fusion plants will pose fewer hazards than fission plants and what other risks technology developers must consider.
  • Government perspective in trying to ensure risks are reduced to as low as reasonably practicable (ALARP) while still creating a positive environment for research and development.
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May 4, 2022 4:05 AM
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Further delays at ITER are certain, but their duration isn’t clear

Further delays at ITER are certain, but their duration isn’t clear | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

A halt to construction, pandemic-caused delays in deliveries, labor strike, and concerns about potential beryllium exposure are among recent challenges to the fusion project.

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May 4, 2022 3:44 AM
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Oxford-Based Start-up May Have Forced Breakthrough In Nuclear Fusion

Oxford-Based Start-up May Have Forced Breakthrough In Nuclear Fusion | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The crown jewel of energy production, nuclear fusion using a projectile, may have been cracked in a major scientific breakthrough by a start-up in Oxford. First Light Fusion (FLF) was praised by business and energy secretary, Kwasi Kwarteng, after it announced it had achieved the reaction in its Kidlington laboratory. The experiment fused two atoms together at very high temperatures, with FLF using a 22-metre gas gun to fire a 100g projectile at 20 times the speed of sound, according to the Telegraph.

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May 4, 2022 3:40 AM
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Nuclear Fusion Might Finally Be Ready for Its Breakthrough Moment

Nuclear Fusion Might Finally Be Ready for Its Breakthrough Moment | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

If you’ve ever been outside during the day, you’ve seen a fusion reactor—though you’re not supposed to stare directly at it. The sun is our fusion reactor in the sky. It’s constantly fusing hydrogen atoms to create helium, and this process generates a massive amount of energy, which produces the light and heat that make life on Earth possible.

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May 4, 2022 3:38 AM
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Nuclear fusion breakthrough achieved with new projectile technique

Nuclear fusion breakthrough achieved with new projectile technique | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Nuclear fusion has been achieved using a new projectile technique that accelerates fuel to 200 times the speed of sound. First Light Fusion, a UK based start-up, used a hyper-velocity gas gun to launch a projectile at fusion fuels, such as deuterium, which starts a reaction. Fusion is a process where two light atomic nuclei combine to form a single heavier one while releasing massive amounts of energy. The team behind the method hopes to create a power plant that could generate around 150 megawatts of electricity by the 2030s.

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May 4, 2022 3:35 AM
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The search for simple and cheap nuclear fusion is on, and these two strategies hold great promise.

The search for simple and cheap nuclear fusion is on, and these two strategies hold great promise. | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Despite its challenges, nuclear fusion holds great promise. So much so that, in fact, some private companies have been born with the intention of proposing new ways more efficient and economical to carry it out. The British First Light Fusion and the Australian HB11 Energy are two of those that seem to have developed the most interesting alternatives to conventional magnetic and inertial confinement, so it is worth taking a look at their proposals.

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May 4, 2022 3:29 AM
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Can the development of fusion energy be accelerated? An introduction to the proceedings

Can the development of fusion energy be accelerated? An introduction to the proceedings | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

This introduction reviews the unique opportunity of fusion power to deliver safe, carbon-free, abundant, base-load power. The differences from fission power are considered: especially why a Chernobyl, Three Mile Island or Fukushima accident could not happen with a fusion reactor. The Lawson triple product is introduced, along with tokamaks, or magnetic bottles, whose ability to approach close to the fusion burn conditions has so far put them above their competitors. Our last fusion power Discussion Meeting was organized by Derek Robinson FRS in 1998, and the progress since then is reviewed. Tokamaks are introduced, and the advantages of spherical tokamaks are listed along with the special engineering challenges that they introduce.

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May 4, 2022 3:26 AM
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Two British companies confident of nuclear fusion breakthrough

Two British companies confident of nuclear fusion breakthrough | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

The failure of sustained attempts to develop fusion power since the 1950s has left the undertaking tainted by claims it is a fool’s errand. But this has not put off investors from backing scientists working on quite different approaches at two private laboratories in Oxfordshire: Tokamak Energy and First Light Fusion. Both have set the ambitious goal of delivering a working reactor ready for commercialisation by 2030, 10 years earlier than the nearby UK Atomic Energy Authority which runs the state-funded fusion programme.

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May 4, 2022 3:21 AM
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UK Startup Makes 'Stunning' Nuclear Fusion Breakthrough

UK Startup Makes 'Stunning' Nuclear Fusion Breakthrough | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

First Light Fusion achieved the stunning reaction using a unique method at its laboratory in Kidlington. The projectile method is reportedly an easier and more efficient technique than other existing approaches to develop what has been referred to develop a fusion reaction.

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May 4, 2022 3:19 AM
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Nuclear Fusion Hit a Milestone Thanks to Better Reactor Walls

Nuclear Fusion Hit a Milestone Thanks to Better Reactor Walls | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

Scientists at a laboratory in England have shattered the record for the amount of energy produced during a controlled, sustained fusion reaction. The production of 59 megajoules of energy over five seconds at the Joint European Torus (JET) experiment in England has been called “a breakthrough” by some news outlets and caused quite a lot of excitement among physicists. But a common line regarding fusion electricity production is that it is “always 20 years away.”

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May 3, 2022 3:48 AM
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Energy From Fusion In 'A Couple Years,' CEO Says, Commercialization In Five

Energy From Fusion In 'A Couple Years,' CEO Says, Commercialization In Five | Local delivery for Gene Directed Enzyme Prodrug Therapy | Scoop.it

TAE Technologies will bring a fusion-reactor technology to commercialization in the next five years, its CEO announced recently at the University of California, Irvine.

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