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Oxygen Therapy and Cellular Regeneration with Dr. Shai Efrati | The Empowering Neurologist EP. 163



Hugh McClung's insight:

Hbot therapy is not well understood but very powerful to  extend health span.Should be part of any preventive practice

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Mayo Clinic's AI-Powered Healthcare Strategy | CXOTalk #829

🔍 Discover how health, data, and AI converge with Dr. John Halamka, a leading figure in healthcare IT. Learn about the Mayo Clinic Platform's mission to accelerate innovation and the ethical curation of global health data. Dive into the challenges of AI model validation and the importance of privacy and trust in healthcare data management.

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Hugh McClung's insight:

Mayo Clinic is a leader in AI health care strategy

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Activating autophagy: a nutritional strategy with longevity applications

Activating autophagy: a nutritional strategy with longevity applications | LongevityBluePrintRx | Scoop.it
As consumers prioritise their healthspan as opposed to their lifespan, the targeted use of dietary spermidine to stimulate autophagy is emerging as a promising healthy ageing approach
Hugh McClung's insight:

As consumers prioritise their healthspan as opposed to their lifespan, the targeted use of dietary spermidine to stimulate autophagy is emerging as a promising healthy ageing approach

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Making "Longevity Laws": Inside this Non-profit's Strategy to Fight Aging | 27 - Dylan Livingston



B
Matt joined the A4LI Board of Directors in 2024.

0:00 Trailer
0:52 Introduction
1:52 A4LI's history and mission
5:34 A4LI's niche in the longevity field
7:38 Some of A4LI's successes
17:14 What's next for A4LI
19:17 A4LI membership


Hugh McClung's insight:

Good effort to inform and mold legistration toward anti aging

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Epigenetic Aging and Rejuvenation – David Sinclair at Longevity Summit Dublin 2023










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Hugh McClung's insight:

Success in epigenetic reprogramming to stop cells at about 80 percent age

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Can Exercise Reduce the Risk of Cancer? | Peter Attia and Rhonda Patrick on Longevity 💪

Hugh McClung's insight:

Yes is the answer frrom two of my favorite longevity people.

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Existing Medicines That Improve Aging Markers | Lifespan.io

Existing Medicines That Improve Aging Markers | Lifespan.io | LongevityBluePrintRx | Scoop.it
The authors of a recent study published in Aging Cell tested 21 groups of medication used by the elderly and reported that some of them impact aging biomarkers [1]. Repurposing existing drugs to fight aging The search […]
Hugh McClung's insight:

The area of repurposed drugs is probably the most attractive area to focus on for anti aging

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5 Longevity Supplements that Turn DOWN Inflammation in the Body

The YouTube video that is titled 5 Longevity Supplements that Turn DOWN Inflammation in the Body, that was produced by the YouTube channel Thomas DeLauer 


Hugh McClung's insight:

In my view, chronic inflammation is the cause of aging. Again, you are in control to controlling inflammation in large part by taking supplements

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US Man, 61, Says He Has Body Of A 38-Year-Old, Shares Biohacking Process

US Man, 61, Says He Has Body Of A 38-Year-Old, Shares Biohacking Process | LongevityBluePrintRx | Scoop.it
Dave Pascoe, a 61-year-old biohacker from Michigan, has garnered attention for claiming to reverse his biological age to that of a 38-year-old through a strict regimen involving diet, exercise, and supplements.
Hugh McClung's insight:

I followed Dave Pascoe's routine. My age is 82, my bio age is 60, I am in perfect health, and I have no chronic diseases.  I believe in bio-hacking your health: hot/cold therapy, red light, hyperbolic  training, Zone 5 with BFR, BrainHQ,  longevity supplements,  fasting, low-carb diet, and meditation

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New wearable aims to give free longevity AI coaching to millions

New wearable aims to give free longevity AI coaching to millions | LongevityBluePrintRx | Scoop.it
Longr’s AI-powered blēo wristband to be made available at no cost to consumers as company seeks to increase access to longevity.
Hugh McClung's insight:

i am trying to get these devices in the Philippines

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Longevity Doctor - How They’re Licensed, Costs & Where to Find One

Longevity Doctor - How They’re Licensed, Costs & Where to Find One | LongevityBluePrintRx | Scoop.it
Longevity doctors are certified doctors who focus on longevity as a specialty.
Hugh McClung's insight:

A good outline of what a longevity doctor is

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Biohacks Tony Robbins uses to reach superhuman energy levels

Biohacks Tony Robbins uses to reach superhuman energy levels | LongevityBluePrintRx | Scoop.it
Business and life strategist Tony Robbins can spend 14 hours a day onstage at his seminars, and he once burned 11,300 calories in just nine hours. Here's how he physically prepares.
Hugh McClung's insight:

these bio hacks are all great and have major impact on your health

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How THIS Natural Ingredients Supplement Addresses All Hallmarks & Reverse Aging?

hy do we age? What are the hallmarks of aging? What we can do to target the hallmarks of aging? In this video, Dr. Nichola Conlon explains what are the hallmarks of aging in details and how we can address multiple hallmarks of aging to slow down or even reverse cellular aging.

Dr. Colon Recent Paper:
A systems-approach to NAD+ restoration
https://www.sciencedirect.com/science/article/pii/S0006295222000405




Hugh McClung's insight:

good presentation on aging

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Can You Hack Your Way to Living to 180? Dave Asprey is Betting His Life on It

Can You Hack Your Way to Living to 180? Dave Asprey is Betting His Life on It | LongevityBluePrintRx | Scoop.it
Dave Asprey, the multimillionaire founder of Bulletproof Coffee, has turned his life into a high-tech laboratory with an ambitious goal: living until 180. 
Hugh McClung's insight:

I think Dave is great and doing the right thing. However, he will not live to 180

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How Moderna's ChatGPT Use Shows the Future of Corporate AI

Moderna's integration of ChatGPT across its entire organization marks a significant shift in corporate AI utilization, aiming to enhance productivity and innovation in various departments. This deal not only bolsters ChatGPT's reach into the enterprise sector but also exemplifies how AI can revolutionize traditional business processes, from drug discovery and regulatory compliance to optimizing manufacturing efficiencies. Learn how Moderna plans to leverage AI to roll out 15 new products in the next five years, reflecting the potential of AI to reshape the biotechnology landscape comprehensively.

The AI Breakdown helps you understand the most important news and discussions in AI.


Hugh McClung's insight:

this is a remarkable example of the future health care organization using Gen AI. This company uses 750 GPT for internal use.

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Mitochondrial restoration therapy could be launch pad for longevity

Mitochondrial restoration therapy could be launch pad for longevity | LongevityBluePrintRx | Scoop.it
Mitrix Bio CEO on how targeting increased longevity for astronauts could also pay dividends for those back on Planet Earth.
Hugh McClung's insight:

We lose as much as 30 or 40% of our mitochondrial DNA by the time we’re in our, let’s say, our 80s, and that means less energy. Our solution is very simple – we want to fill you back up with functional mitochondria by pushing the ratio of dysfunctional mitochondria to functional mitochondria back towards the younger state. It’s mitochondrial restoration – putting in more functional mitochondria.

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The coupling between healthspan and lifespan in Caenorhabditis depends

The coupling between healthspan and lifespan in Caenorhabditis depends | LongevityBluePrintRx | Scoop.it
“The ultimate goal of exploiting model organisms to screen for anti-aging interventions is to identify treatments that might translate to healthy lifespan extension in humans.”Credit: 2024 Banse et al.
Hugh McClung's insight:

“The ultimate goal of exploiting model organisms to screen for anti-aging interventions is to identify treatments that might translate to healthy lifespan extension in humans.”

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Rubedo lands $40m to advance senescence-targeting therapeutics into clinical trials

Rubedo lands $40m to advance senescence-targeting therapeutics into clinical trials | LongevityBluePrintRx | Scoop.it
Longevity biotech plans Phase 1 senotherapeutics trial this year as it seeks to keep people 'biologically young.'...
Hugh McClung's insight:

The company’s Alembic drug discovery platform facilitates the identification of specific druggable targets, with a focus on senescent cells associated with various chronic disorders.

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Cheap longevity drug? Researchers aim to test if metformin can slow down aging : Shots - Health News

Cheap longevity drug? Researchers aim to test if metformin can slow down aging : Shots - Health News | LongevityBluePrintRx | Scoop.it
Studies suggest people who take metformin for diabetes may be at lower risk for cancer, heart disease and dementia. Now researchers aim to test if it prevents age-related diseases in healthy people.
Hugh McClung's insight:

I take metformin as part of my anti aging routine

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Longer-Lived People Have Less Epigenetic Noise | Lifespan.io

Longer-Lived People Have Less Epigenetic Noise | Lifespan.io | LongevityBluePrintRx | Scoop.it
A team of researchers has reported in Aging Cell that longer-lived Chinese women have less epigenetic noise in crucial areas of the genome. Order and disorder We have previously reported that the accumulation of epigenetic noise appears to be the […]
Hugh McClung's insight:

Again supports the theory that gene are associated with anti-aging in certain people

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What is a Longevity Coach & How to Find One

What is a Longevity Coach & How to Find One | LongevityBluePrintRx | Scoop.it
A longevity coach is a health or wellness professional that focuses on lifestyle choices that can promote a longer and healthier life.
Hugh McClung's insight:

When a doctor practices longevity medicine they really are a longevity coach

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IISc Launches ‘Longevity India Initiative’ to Pioneer Ageing Research in India

IISc Launches ‘Longevity India Initiative’ to Pioneer Ageing Research in India | LongevityBluePrintRx | Scoop.it
The Indian Institute of Science IISc announces the launch of the Longevity India Initiative a project focused on efforts to extend human healthspan and tackle ageingrelated challenges.
Hugh McClung's insight:

this is type of program all governement should consider

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Rapamycin and Longevity: A Few Thoughts On Dosing

Rapamycin and Longevity: A Few Thoughts On Dosing | LongevityBluePrintRx | Scoop.it
Rapamycin may be a potent longevity drug, but how should you think about dosing it for the optimum health and life extension effects?
Hugh McClung's insight:

I take Rapamycin once a wee for a dose of 6mg

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Senolytics May Delay the Aging of Ovaries | Lifespan.io

Senolytics May Delay the Aging of Ovaries | Lifespan.io | LongevityBluePrintRx | Scoop.it
A recent paper published in Nature Aging dives into the gene expression differences between young, middle-aged, and older human ovaries and tests possible interventions to slow down their aging processes [1]. An underexplored area of human aging Female […]
Hugh McClung's insight:

Aging research with a focus on women is behind. Interesting study on improving female aging

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5 podcast episodes that will teach you about longevity, healthy aging

5 podcast episodes that will teach you about longevity, healthy aging | LongevityBluePrintRx | Scoop.it
Looking to learn more about the factors that contribute to longevity and aging gracefully? Listen to these five podcast episodes for longevity hacks.
Hugh McClung's insight:

Good reference lists

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Accelerated aging may be a cause of increased cancers in people under 55

Accelerated aging may be a cause of increased cancers in people under 55 | LongevityBluePrintRx | Scoop.it
An increase in cancers among people 55 years old and younger may be related to accelerated aging in recent generations, according to a study presented at a conference earlier this month. Experts say years of research support this, though more questions remain to be answered.
Hugh McClung's insight:

Lifestyle factors, mainly lack for younger people, contribute to cancer. Not surprising

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