Immunology and Biotherapies
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Immunology and Biotherapies
Page Ressources et Actualités du DIU immunologie et biothérapies
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Scooped by Gilbert C FAURE
April 17, 2014 1:41 PM
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ADC Market Anticipated to Reach US$ 3.45 Bn by 2018

ADC Market Anticipated to Reach US$ 3.45 Bn by 2018 | Immunology and Biotherapies | Scoop.it
According to a new report published this month (Global Antibody Drug Conjugate Market Outlook 2018) the ADC market is anticipated to reach US$ 3.45 Billion by 2018.
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Rescooped by Gilbert C FAURE from Top Selling Monoclonal Antibodies
January 6, 2014 8:51 AM
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Best Selling Monoclonal Antibodies 2013

Best Selling Monoclonal Antibodies 2013 | Immunology and Biotherapies | Scoop.it

Via Krishan Maggon
Gilbert C FAURE's insight:

impressive for immunologists so far away from so big amounts of money

Krishan Maggon 's curator insight, January 6, 2014 8:38 AM

Abstract

 

A review of the best selling monoclonal antibodies in 2013 and 2012 is provided. Humira with sales of over $11 billion ($9.3 billion in 2012) remains the best selling monoclonal antibody, biologic as well prescription drug brand in 2013 as in 2012. The ranks of the next 4 top selling mabs remained unchanged from the 2012 Table.  Remicade (9.7 Bn), Rituxan (7.5 Bn) , Herceptin (6.5 Bn) and Avastin (6.5 Bn) were the second, third, fourth and fifth top selling mabs in 2013. The actual sales for 2013 as reported by the companies are provided. The total sales of the top selling blockbuster mabs were $63 billion in 2013. The actual global sales of all the approved blockbuster sales or potential (sales >1 billion) monoclonal antibodies in 2013 is provided. Besides the top 5 mabs, there were 2 other monoclonal antibodies with sales of over 2 billion dollars and 5 with sales of over $ 1 billion in 2013. In addition 5 recently launched mabs were nearing to reach sales of $ 1 billion this year. Currently 30 monoclonal antibodies are marketed in the US and Europe (January 2014).  Alexion Soliris was the most expansive marketed monoclonal antibody with a price tag of $440,000 per year of treatment, a sort of Rolls-Royce of mabs.

 

Scooped by Gilbert C FAURE
October 16, 2013 2:56 PM
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Sutro Biopharma Presents Dual-Warhead Antibody Drug Conjugate at the World ... - PR Newswire (press release)

Sutro Biopharma Presents Dual-Warhead Antibody Drug Conjugate at the World ...
H. Fai Poon's curator insight, October 17, 2013 4:46 AM

Duble ADC!!! More is better?

Scooped by Gilbert C FAURE
September 29, 2013 2:49 PM
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Can an antibody drug conjugate (ADC) be greater than the sum of its parts?

Roche is at the forefront in developing antibody-drug conjugates (ADCs) that combine the specificity of antibodies with the power of chemotherapy. This video... (RT @Roche: Roche is at the forefront in developing antibody-drug conjugates.
Gilbert C FAURE's insight:

Roche on youtube!

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Scooped by Gilbert C FAURE
September 1, 2013 11:26 AM
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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate ...

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate ... | Immunology and Biotherapies | Scoop.it
Key Points. SGN-CD33A is a novel antibody-drug conjugate, consisting of an engineered anti-CD33 mAb conjugated to a potent DNA cross-linking cytotoxin. SGN-CD33A is highly active in a broad panel of preclinical AML ...
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Scooped by Gilbert C FAURE
May 30, 2013 2:15 PM
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Immunomedics Presents Clinical Progress of Antibody-Drug Conjugate ... - GlobeNewswire (press release)

Immunomedics Presents Clinical Progress of Antibody-Drug Conjugate ...
GlobeNewswire (press release)
MORRIS PLAINS, N.J., May 30, 2013 (GLOBE NEWSWIRE) -- Immunomedics, Inc.
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Scooped by Gilbert C FAURE
January 29, 2013 2:04 PM
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New Drug Application Filed for Antibody-Drug Conjugate Trastuzumab ... - PharmaLive (press release) (subscription)

New Drug Application Filed for Antibody-Drug Conjugate Trastuzumab ...
PharmaLive (press release) (subscription)
January 29, 2013 (Tokyo) – Chugai Pharmaceutical Co., Ltd. [Main Office: Chuo-ku, Tokyo.
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Scooped by Gilbert C FAURE
January 8, 2013 11:16 AM
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Lonza to Expand Antibody Drug Conjugate (ADC) Manufacturing Capacity to Meet Growing Customer Demand

Lonza to Expand Antibody Drug Conjugate (ADC) Manufacturing Capacity to Meet Growing Customer Demand | Immunology and Biotherapies | Scoop.it
Lonza to Expand Antibody Drug Conjugate (ADC) Manufacturing Capacity to Meet Growing Customer Demand (RT @LonzaGroup: Lonza to Expand Antibody Drug Conjugate (ADC) Manufacturing Capacity to Meet Growing Customer Demand -
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Scooped by Gilbert C FAURE
October 31, 2012 4:48 PM
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EC Conditionally Sanctions Antibody-Drug Conjugate - Genetic Engineering News

EC Conditionally Sanctions Antibody-Drug Conjugate - Genetic Engineering News | Immunology and Biotherapies | Scoop.it
The Herald | HeraldOnline.comEC Conditionally Sanctions Antibody-Drug ConjugateGenetic Engineering NewsThe EC granted conditional approval for Seattle Genetics and Millennium's antibody-drug conjugate (ADC) Adcetris (brentuximab vedotin) for two indications:...
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Scooped by Gilbert C FAURE
October 3, 2012 2:07 PM
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Intellect Neurosciences and iNovacia Enter Research Service Agreement to ... - NASDAQ

Intellect Neurosciences and iNovacia Enter Research Service Agreement to ... - NASDAQ | Immunology and Biotherapies | Scoop.it
Intellect Neurosciences and iNovacia Enter Research Service Agreement to ...NASDAQWe believe the antibody drug conjugate will show improved efficacy compared to the naked amyloid beta antibodies currently in clinical development for AMD.
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Scooped by Gilbert C FAURE
July 31, 2012 11:45 AM
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Mersana Therapeutics Inc Raises 27 Million to

CAMBRIDGE, Mass. July 31, 2012 - Mersana Therapeutics, Inc., a biopharmaceutical company developing its Fleximer® antibody-drug conjugate platform and (Mersana Therapeutics, Inc.
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Scooped by Gilbert C FAURE
March 5, 2014 1:25 PM
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Building Better Therapeutic Antibodies - The Biological SCENE

Building Better Therapeutic Antibodies - The Biological SCENE | Immunology and Biotherapies | Scoop.it
The Biological SCENE Building Better Therapeutic Antibodies The Biological SCENE To make an antibody-drug conjugate, researchers added galactose (purple circles) and sialic acid (blue triangles) to carbohydrate chains (open shapes) on a...
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Scooped by Gilbert C FAURE
November 17, 2013 1:52 PM
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In the spotlight: a novel CD37 antibody-drug conjugate

In the spotlight: a novel CD37 antibody-drug conjugate | Immunology and Biotherapies | Scoop.it
RT @DrAnasYounes: In the spotlight: a novel CD37 antibody-drug conjugate for B cell lymphoma... http://t.co/KFn1CDmqrT
Gilbert C FAURE's insight:

a tetraspanin as target?

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Scooped by Gilbert C FAURE
October 15, 2013 3:10 PM
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INNATE PHARMA: presents proprietary antibody-drug conjugate technology at ... - Wall Street Journal

INNATE PHARMA: presents proprietary antibody-drug conjugate technology at ... - Wall Street Journal | Immunology and Biotherapies | Scoop.it
INNATE PHARMA: presents proprietary antibody-drug conjugate technology at ...
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Scooped by Gilbert C FAURE
September 20, 2013 1:45 PM
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Roche - CHMP grants positive opinion for Roche’s Kadcyla, the first antibody-drug conjugate for advanced HER2-positive breast cancer

Roche - CHMP grants positive opinion for Roche’s Kadcyla, the first antibody-drug conjugate for advanced HER2-positive breast cancer | Immunology and Biotherapies | Scoop.it
CHMP grants positive opinion for Roche's Kadcyla, the first antibody-drug conjugate for advanced HER2-positive... http://t.co/feKQV88y7T
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Scooped by Gilbert C FAURE
June 18, 2013 8:17 AM
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Genmab, ADC partner to develop new antibody-drug conjugate to treat cancer - Pharmaceutical Business Review

Genmab, ADC partner to develop new antibody-drug conjugate to treat cancer Pharmaceutical Business Review The collaboration will integrate Genmab's high-affinity fully human antibody targeting CD25, HuMax-TAC, with ADC's PBD-based warhead and...
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Scooped by Gilbert C FAURE
March 8, 2013 1:44 PM
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Biotech Industry Soars in 2012 as FDA Drug Approvals Reach a 15-Year High - Marketwire (press release)

Biotech Industry Soars in 2012 as FDA Drug Approvals Reach a 15-Year High - Marketwire (press release) | Immunology and Biotherapies | Scoop.it
Biotech Industry Soars in 2012 as FDA Drug Approvals Reach a 15-Year High Marketwire (press release) Progenics' pipeline candidates include PSMA ADC, a human monoclonal antibody-drug conjugate in phase 2 testing for treatment of prostate cancer,...
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Scooped by Gilbert C FAURE
January 15, 2013 2:37 PM
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Long-term Tumor Regression Induced by an Antibody–Drug Conjugate That Targets 5T4, an Oncofetal Antigen Expressed on Tumor-Initiating Cells

RT @AACR: Long-term Tumor Regression Induced by an Antibody–Drug Conjugate That Targets 5T4 http://t.co/dR8No5I1 #AACR #journal
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Scooped by Gilbert C FAURE
December 26, 2012 1:58 PM
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GEN | Magazine Articles: Cancer Research Firms Eye ADCs to Extend Portfolios

GEN | Magazine Articles: Cancer Research Firms Eye ADCs to Extend Portfolios | Immunology and Biotherapies | Scoop.it
Antibody drug conjugates ease development of new targets or conjugate potent payloads to existing mAbs.
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Scooped by Gilbert C FAURE
October 24, 2012 2:36 AM
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Abbott and Seattle expand antibody-drug conjugate collaboration - NEWS - General articles - Pharmaceutical Industry - PMLiVE

Abbott and Seattle expand antibody-drug conjugate collaboration - NEWS - General articles - Pharmaceutical Industry - PMLiVE | Immunology and Biotherapies | Scoop.it
Pharmaceutical Industry | NEWS | General | Abbott and Seattle expand antibody-drug conjugate collaboration - Pharma company could pay $220m per oncology target | PMLiVE (#oncology Abbott and Seattle expand antibody-drug conjugate collaboration
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Scooped by Gilbert C FAURE
September 9, 2012 2:03 PM
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"BT-062: An Antibody Drug Conjugate Targeting CD138 for the Treatment of Cancer"

"BT-062: An Antibody Drug Conjugate Targeting CD138 for the Treatment of Cancer" | Immunology and Biotherapies | Scoop.it
In the run up to World ADC (23 - 25 October 2012, San Francisco), I'd like to share with you a presentation delivered by Chantal Zuber, Manager, Research Immunology, Biotest.
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Scooped by Gilbert C FAURE
July 20, 2012 3:37 PM
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Biotest’s Antibody-drug Conjugate BT-062 In Multiple Myeloma Combination Therapy

Biotest’s Antibody-drug Conjugate BT-062 In Multiple Myeloma Combination Therapy | Immunology and Biotherapies | Scoop.it
Biotest’s Antibody-drug Conjugate BT-062 In Multiple Myeloma Combination Therapy (#clinicaltrials Biotest’s Antibody-drug Conjugate BT-062 In Multiple Myeloma Combination Therapy: BT-062, an ant...)...
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