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The method uses small molecules called "micro-RNAs," delivered by a virus into the spinal fluid, to block a gene key in the fatal nerve disease ALS, also known as Lou Gehrig's disease. 
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Boston, MA (November 28, 2018) — Several ALS organizations announced on Wednesday that the first participant was successfully given a dose of AT-1501 in the first in-human trial of the potential treatment for ALS. AT-1501 was developed by the ALS Therapy Development Institute (ALS TDI), with support from The ALS Association, ALS ONE, and ALS Finding a Cure®, and is being brought into trials by Anelixis Therapeutics, Inc., a for-profit subsidiary of ALS TDI.
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The Ice Bucket Challenge helped raise over $220 million in only a few weeks.
"The research that has contributed to Maynard's potentially life-changing therapy has changed dramatically since five years ago, when the grim reality of ALS was pushed into the spotlight with the help of the Ice Bucket Challenge in 2014. Videos went viral showing millions of people pouring ice-cold water over themselves and then nominating others to do the same in an effort to raise awareness and fund research into the neuro degenerative disease". #Brainstorm #StemCellTherapy #IceBucketChallenge
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