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Effects of HMGB1 on proliferation and apoptosis of human brain glioma CD133 cells
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The aim of this work is to understand the effects of HMGB1 recombinant lentivirus vector on proliferation and apoptosis on CD133 cells after transfecting a human glioma cell strain CD133. The scientists observe that lentiviral vector is a very efficient tool to tranduce human glioma cell line CD133 and that over-expression of HMGB1 is able to inhibit proliferation of tumor cells and promote apoptosis.
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