In this study, the authors knocked down or ectopically expressed miR-223 in cord blood CD34+ cells using lentiviral vectors. While miR-223 knockdown delayed myelo-erythroid precursor differentiation in vitro, it increased myeloid progenitors in vivo following serial xenotransplantation. Ectopic miR-223 expression increased erythropoiesis, T and early B lymphopoiesis in vivo.
To get content containing either thought or leadership enter:
To get content containing both thought and leadership enter:
To get content containing the expression thought leadership enter:
You can enter several keywords and you can refine them whenever you want. Our suggestion engine uses more signals but entering a few keywords here will rapidly give you great content to curate.
In this study, the authors knocked down or ectopically expressed miR-223 in cord blood CD34+ cells using lentiviral vectors. While miR-223 knockdown delayed myelo-erythroid precursor differentiation in vitro, it increased myeloid progenitors in vivo following serial xenotransplantation. Ectopic miR-223 expression increased erythropoiesis, T and early B lymphopoiesis in vivo.
www.geg-tech.com/Vectors