Genetically modified mesenchymal stem cells have been used in attempts to increase the expression of interleukin‑1 receptor antagonist (IL‑1Ra); however, the attempts thus far have been unsuccessful. In this sutdy, the scientists designed a lentiviral vector which is able to efficiently express exogenous Il‑1Ra in murine bone marrow‑derived mesenchymal stem cells under certain conditions and had a marked capacity for proliferation.
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Genetically modified mesenchymal stem cells have been used in attempts to increase the expression of interleukin‑1 receptor antagonist (IL‑1Ra); however, the attempts thus far have been unsuccessful. In this sutdy, the scientists designed a lentiviral vector which is able to efficiently express exogenous Il‑1Ra in murine bone marrow‑derived mesenchymal stem cells under certain conditions and had a marked capacity for proliferation.
www.geg-tech.com/Vectors