Generating CRISPR mouse models: Challenges and solutions | SynBioFromLeukipposInstitute | Scoop.it
The discovery of the CRISPR/Cas9 system in bacteria has ignited the world of gene editing. It has been applied to the modification of a growing range of organisms, with none found yet that can resist its powers. In particular, CRISPR technology has revolutionized the process for creating genetically modified mice—the workhorses for in vivo cancer research—allowing for shorter timelines and in many cases, more efficient procedures.