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Novo Nordisk to launch connected insulin pens

From www.pmlive.com October 1, 2018 10:35 AM

Many diabetes patients have been calling for ‘smart’, internet-connected pens to monitor their condition, but the technology has been slow to arrive.

Now, Novo Nordisk has announced that it will globally launch two ‘connected’ insulin pens, which will be able to communicate with continuous glucose monitoring (CGM) systems and blood glucose meters (BGM).

This looks to be the start of the long-awaited digital integration, which has been held back by safety concerns, competitive interests and incompatible digital platforms.

Novo Nordisk’s biggest competitors in diabetes injectables are Eli Lilly and Sanofi, but looks to be ahead of its rivals in rolling out a joined-up digital solution, announcing plans to make two durable, connected insulin pens NovoPen 6 and NovoPen Echo Plus commercially available across key markets from early 2019.

In addition to demand from patients, healthcare payers, especially in the US, are calling for comprehensive disease management platforms.

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Sometimes #Pharma "Innovation" Doesn't Make Good Business Sense: Merck/Diabetes Case Study

From www.pmlive.com April 17, 2016 3:40 AM

Merck & Co will no longer file for approval of once-weekly diabetes drug omarigliptin in the US or Europe.

The company said in a statement that the decision did not relate to any safety or efficacy issues with the DPP-4 inhibitor, which might suggest it is not confident that the market is prepared to pay a premium for a weekly compared to a once-daily drug such as Merck's own Januvia (sitagliptin) product.

There are thought to be other issues with once-weekly administration of DPP-4 inhibitors. While they are intended to reduce the burden of taking pills by diabetics and improve compliance, patients can rarely benefit from drug-free days as those on DPP-4 inhibitors often also take metformin, which must be dosed every day.

Some clinicians argue that it is easier for patients to keep track of dosing two drugs side by side rather than mixing weekly and daily doses.

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