Encouraging interim data from the world’s first clinical trial examining the safety of neural stem cell treatment in ischemic stroke patients has been reported by researchers ahead of an application for Phase II trials.
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NEW YORK (Reuters Health) - Among people with advanced cancer, poorer patients are less likely to be referred for clinical trials of experimental drugs, a new study from the UK suggests.
Because those early trials will eventually help regulators decide if drugs should be approved for a wider population, it's important that test patients be representative of people the medications are designed to treat, researchers said.
In addition, "There is an ethical issue of access to trials, because in general (for these patients), the standard therapeutic options have been exhausted," said James Spicer from King's College London and Guy's Hospital, who worked on the study.
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GE Healthcare recently announced that Clarient Diagnostic Services, Inc., a GE Healthcare company, will begin offering a next-generation sequencing assay focused on solid tumor targets for use in clinical trials. This assay will empower researchers to perform prospective and retrospective analysis to better understand which patients will respond to particular therapies, to help stratify patient populations for ongoing clinical trials, and to aid early research efforts.
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In a modern-day clinical trial of a medicine belonging to one of the world's oldest classes of drugs, researchers have found that a drug related to aspirin and salicylate, which was first used by ancient Egyptians and Greeks to ease pain caused by inflammation, also has glucose-lowering properties and may be a potential treatment for people with type 2 diabetes, according to results presented at the American Diabetes Association's 72nd Scientific Sessions(R).
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