Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis, resulting in peripheral blood cytopenias, myeloid dysplasia and risk of leukemic transformation.
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Leukemia (2014) 28, 189–192; doi:10.1038/leu.2013.195; published online 16 July 2013
The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDSA M Aalbers et al.