RT @RIRDF: NIH Scientists Identify a New Immunodeficiency Disease http://t.co/CP96Q4OVcI
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Link to the Nature Immunology Paper: http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.2771.html
The study has identified a novel immunodeficiency disease called PASLI, its underlying genetic cause, and a promising, targeted treatment that is already FDA-approved for other purposes. The discovery of PASLI disease also contributes to our understanding of the immune system and highlights the role of PI3K-p110 delta and mTOR in immunity.