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Low levels of vitamin-D are associated with neuropathy and lymphoma among patients with Sjögren’s syndrome
Nancy Agmon-Levina, 1,Shaye Kivitya, b, c, 1,Athanasios G. Tzioufasd,Marcus López Hoyose,Blaz Rozmanf,Inga Efesa,Yinon Shapiraa,Ari Shamisg,Howard Amitala,Pierre Youinouh, i,Yehuda Shoenfeldj, ,
Background/purpose
Primary Sjögren’s syndrome (SS) is a chronic autoimmune disease primarily involving the exocrine glands. The clinical picture of SS ranges from exocrinopathy to systemic disease affecting the lung, kidney, liver, skin, musculockeletal and nervous systems. The morbidity of SS is mainly determined by extraglandular disease and increased prevalence of lymphoma. Environmental and hormonal factors, such as vitamin-D may play a role in the pathogenic process and disease expression. Thus, we aimed to evaluate levels of vitamin-D and their association with manifestations of SS.
Complete text: http://www.sciencedirect.com/science/article/pii/S0896841112000856
