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Immunopathology & Immunotherapy
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Latest advances in immunopathology diagnosis and treatment
Curated by
Alfredo Corell
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This study examines differences in microbial colonization and community stability in PID skin and informs our understanding of host–microbiome interactions, suggesting a bidirectional dialogue between skin commensals and the host organism.
Alfredo Corell's insight:
The altered landscape of the human skin microbiome in patients with primary immunodeficienciesJulia Oh1, Alexandra F. Freeman2, NISC Comparative Sequencing Program3, Morgan Park3, Robert Sokolic1, Fabio Candotti1,Steven M. Holland2, Julia A. Segre1,5,6 and Heidi H. Kong4,5,6Article published online before print. Article, supplemental material, and publication date are athttp://www.genome.org/cgi/doi/10.1101/gr.159467.113. 
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"A blog about allergy, asthma & immunology" (I'm looking at http://t.co/n7OsWY6IYd "Allergy, Asthma and Immunology")
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Scientists show that mice housed at room temperature are less able to fight tumors.
Alfredo Corell's insight:
K.M. Kokolus et al., “Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature,” PNAS, doi:10.1073/pnas.1304291110, 2013.
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El ácido lipoico favorece la generación de células de microglía y fagocitarias del sistema inmune, lo que agiliza la restauración de los tejidos cerebrales dañados
Alfredo Corell's insight:
CEU-UHC/DICYT Investigadores del Instituto de Ciencias Biomédicas de la Universidad CEU Cardenal Herrera de Valencia (CEU-UCH), la Facultad de Ciencias de la Salud de esta Universidad y la Facultad de Medicina de la Universidad de Barcelona han dado un nuevo paso en sus investigaciones sobre el uso de antioxidantes para favorecer la regeneración de los tejidos neuronales tras una lesión cerebral. Su último estudio, publicado en la revista Clinical and Developmental Immunology, ha permitido comprobar que la respuesta inmune del cerebro ante una lesión cerebral se acelera con la administración de ácido lipoico.
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Who would dare to pit one fatal disease against another… inside the body of a six-year-old patient? The results will shatter all expectations.
Alfredo Corell's insight:
ROSS KAUFFMAN A seven-year-old girl has been 'cured' of leukaemia after a new therapy in which her T-cells — the immune system's killer cells — were bio-engineered to become 'guided missiles' to seek out and destroy the leukaemia, a new study shows. Read more: http://www.dailymail.co.uk/health/article-2246008/Girl-7-cured-leukaemia-scientists-reprogramme-immune-cells-destroy-cancer.html#ixzz2FFTBJNCy
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THE BIRTH OF IMMUNOLOGY:
The work of Behring and Kitasato not only proved that indeed “[b]lood is a very unusual fluid,” it also represented a major step in the discovery of antibodies, the development of effective human vaccines and the birth of immunology.