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The increasing incidence of acyclovir (ACV) and multidrug-resistant strains in patients with corneal HSV-1 infections leading to Herpetic Stromal Keratitis (HSK) is a major health problem in industrialized countries and often results in blindness.
Via Krishan Maggon
* E-mail: adalbert.krawczyk@uni-due.de
Affiliation: Institute of Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⨯Miriam Dirks,Affiliation: Institute of Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⨯Maren Kasper,Affiliation: Ophtha-Lab, Department of Ophthalmology at St. Franziskus Hospital, Muenster, Germany
⨯Anna Buch,Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany
⨯Ulf Dittmer,Affiliation: Institute of Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⨯Bernd Giebel,Affiliation: Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany
⨯Lena Wildschütz,Affiliation: Ophtha-Lab, Department of Ophthalmology at St. Franziskus Hospital, Muenster, Germany
⨯Martin Busch,Affiliation: Ophtha-Lab, Department of Ophthalmology at St. Franziskus Hospital, Muenster, Germany
⨯Andre Goergens,Affiliation: Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany
⨯Karl E. Schneweis,Affiliation: Institute of Virology, University Medical Center Bonn, Bonn, Germany
⨯Anna M. Eis-Hübinger,Affiliation: Institute of Virology, University Medical Center Bonn, Bonn, Germany
⨯Beate Sodeik,Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany
⨯Arnd Heiligenhaus,Affiliation: Ophtha-Lab, Department of Ophthalmology at St. Franziskus Hospital, Muenster, Germany
⨯Michael Roggendorf,Affiliation: Institute of Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⨯Dirk BauerAffiliation: Ophtha-Lab, Department of Ophthalmology at St. Franziskus Hospital, Muenster, Germany
⨯ Published: January 14, 2015DOI: 10.1371/journal.pone.0116800